Chemoenzymatic Total Syntheses of the Enantiomers of the Protoilludanes 8‑Deoxydihydrotsugicoline and Radudiol par Ee Ling Chang (1818994)

“…Chemoenzymatic and stereoselective total syntheses of the non-natural enantiomeric forms of the recently isolated protoilludane natural products 8-deoxydihydrotsugicoline (<b>1</b>) and radudiol (<b>2</b>) (viz. …”

<b>Two-photon excitation fluorescence </b><b>microspectroscopy protocols for examining </b><b>fluorophores in fossil plants</b> par Michael Stoneman (8681826)

“…By applying linear spectral unmixing to the spectrally resolved fluorescence images, we could differentiate between (a) the matrix and (b) the original biological material or chemical products formed during fossilization. …”

A comprehensive phylogenetic analysis on early ornithischian evolution par André O. Fonseca (18863173)

“…<p>Resolving the evolutionary relationships of early diverging (‘basal’) ornithischian dinosaurs is a challenging topic in palaeontology, with multiple competing hypotheses on the phylogenetic relationships of heterodontosaurids, ‘hypsilophodontids’, and other early-diverging forms. …”

Photoionization Mass Spectrometric Measurements of Initial Reaction Pathways in Low-Temperature Oxidation of 2,5-Dimethylhexane par Brandon Rotavera (1303167)

“…Interpretation of time- and photon-energy-resolved mass spectra led to three specific results important to characterizing the initial oxidation steps: (1) quantified isomer-resolved branching ratios for HO₂ + alkene channels; (2) 2,2,5,5-tetramethyltetrahydrofuran is formed in substantial yield from addition of O₂ to tertiary 2,5-dimethylhex-2-yl followed by isomerization of the resulting ROO adduct to tertiary hydroperoxyalkyl (QOOH) and exhibits a positive dependence on temperature over the range covered leading to a higher flux relative to aggregate cyclic ether yield. …”

The AAT G349R variant has a defective inhibitory mechanism. par Mattia Laffranchi (6199643)

“…<p><b>(A)</b> Cell media of HEK293T transfected cells were incubated with (+) or without (–) equimolar or double concentrations of neutrophil elastase (HNE) for 30 min at 37°C, and the complexes (68 kDa, dark arrow) were resolved from unreacted AAT monomers (52 kDa) or cleaved forms (48 kDa, white arrow) by 7.5% w/v acrylamide SDS–PAGE and immunoblot with anti-AAT pAb. …”

“Bind and Crawl” Association Mechanism of <i>Leishmania major</i> Peroxidase and Cytochrome <i>c</i> Revealed by Brownian and Molecular Dynamics Simulations par James B. Fields (1461250)

“…The association of LmP and LmCytc, which is known from kinetics measurements to be very fast (∼10⁸ M^–1 s^–1), does not involve major conformational changes and has been suggested to be dominated by electrostatic interactions. …”

Image_2_Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018.tif par Alba Kaci (16510404)

“…We also revealed extensive intra-species recombination events involving surface exposed virulence factors, including the emm gene important for phylogenetic profiling.…”

PyntaAn Automated Workflow for Calculation of Surface and Gas–Surface Kinetics par Matthew S. Johnson (16809951)

“…Manually calculating these parameters is tedious and error prone, involving many interconnected computations. We present Pynta, a workflow software for automating the calculation of surface and gas–surface reactions. …”

Table1_The phenotypic and genetic features of arrhythmogenic cardiomyopathy in the pediatric population.docx par Olga Kofeynikova (16989483)

“…Four patients carried compound heterozygous variants in desmosomal genes associated with left ventricular involvement.</p>Conclusion<p>Arrhythmias and structural heart disease, such as chamber dilatation, should raise suspicion of different ACM phenotypes. …”

Table_2_Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018.XLSX par Alba Kaci (16510404)

“…We also revealed extensive intra-species recombination events involving surface exposed virulence factors, including the emm gene important for phylogenetic profiling.…”

Analysis of Antiviral Response in Human Epithelial Cells Infected with Hepatitis E Virus par Pradip B. Devhare (411569)

“…However, absence of secreted interferons till 96 h suggested possible involvement of post-transcriptional regulation of type I IFN expression. …”

PyntaAn Automated Workflow for Calculation of Surface and Gas–Surface Kinetics par Matthew S. Johnson (16809951)

“…Manually calculating these parameters is tedious and error prone, involving many interconnected computations. We present Pynta, a workflow software for automating the calculation of surface and gas–surface reactions. …”

Image_1_Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018.tif par Alba Kaci (16510404)

“…We also revealed extensive intra-species recombination events involving surface exposed virulence factors, including the emm gene important for phylogenetic profiling.…”

Table_1_Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018.XLSX par Alba Kaci (16510404)

“…We also revealed extensive intra-species recombination events involving surface exposed virulence factors, including the emm gene important for phylogenetic profiling.…”

Data Sheet 1_Cluster analysis of cutting technique—a valuable approach for assessing anterior cruciate ligament injury risk?.pdf par Lasse Mausehund (20697173)

“…</p>Results<p>We identified two distinguishable cutting technique clusters in the subset involving both sports and five kinematics variables (average silhouette score, ASS = 0.35). …”

Table_1_Phylogeography of the giant honey bees based on mitochondrial gene sequences.xlsx par Chet P. Bhatta (13726272)

“…However, our analysis did not resolve the phylogenetic relationships among the four lineages. …”

table1_Switchable Coumarins for Ratiometric pH Sensing.docx par Mercedes M. A. Mazza (7522499)

“…As a result, an equilibrium between two species with resolved fluorescence is established with fast kinetics in aqueous environments. …”

HTLV-1 induces degradation of endogenous IRF3. par Stéphanie Olière (238189)

“…Western blot analysis was used to locate monomer and dimer forms of IRF3 in the non-denaturing gel (upper panel), and global IRF3 protein in the denaturing gel (lower panel). …”

Benzyltriboronates: Building Blocks for Diastereoselective Carbon–Carbon Bond Formation par W. Neil Palmer (1419946)

“…A highly diastereoselective carbon–carbon bond-forming reaction involving the tandem coupling of benzyltriboronates, enoates, and alkyl halides is described. …”

Structural features differentiating active (magenta) and inactive (blue) states in apo RIPK2. par Shray Vats (19493706)

“…Flipping of Trp170 destabilizes the activation loop which breaks the H-bond interaction involving Arg65 and Ser168, inducing a shift in αC helix. …”