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30781
Non-covalent interactions between Akt1/Akt2-IN-1 (ball stick) and the AKT2 protein as predicted by molecular docking analyses.
Published 2025“…<b>(b)</b> In the Y265N mutant, interactions involve Pi–anion bonding with GLU236, Pi-sulfur interactions with LYS277, and Pi-alkyl contacts with GLU279, GLU315, PHE238, PHE163, LYS277, VAL166, and MET282, and Pi-Sigma interaction with GLU315. …”
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30782
Covalent Bonding and Atomic-Level Plasticity Increase Adhesion in Silicon–Diamond Nanocontacts
Published 2019“…First, covalent bonds formed across the interface, where the number of bonds formed was affected by the hydrogen termination of the substrate, the tip roughness, the applied stress, and the stochastic nature of bond formation. …”
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30783
Lewis Acid Catalyzed Three-Component Hetero-Diels−Alder (Povarov) Reaction of <i>N</i>-Arylimines with Strained Norbornene-Derived Dienophiles
Published 2010“…These observations may be rationalized by two competing mechanistic models, involving either a concerted asynchronous [4 + 2]-like mechanism or a stepwise mechanism.…”
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30784
Efficient Non-Viral Reprogramming of Myoblasts to Stemness with a Single Small Molecule to Generate Cardiac Progenitor Cells
Published 2011“…<div><p>The current protocols for generation of induced pluripotent stem (iPS) cells involve genome integrating viral vectors which may induce tumorgenesis. …”
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30785
Space-time distribution of manganese ore deposits along the southern margin of the South China Block, in the context of Palaeo-Tethyan evolution
Published 2017“…The carbonate C–O isotope and ore trace element composition data suggest that ore-forming fluids were dominated by seafloor water with involvement of magmatic hydrothermal fluids and organic matter as well. …”
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30786
The activity of gluconeogenesis enzymes.
Published 2013“…The method is based on a coupled enzyme reaction in which glucose formed is reacted with glucose oxidase and peroxidase and the quinoneimine formed is a colored product and its formation can be followed spectrophotometrically at 510 nm.…”
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30787
The Tetracyanopyrazinide Dimer Dianion, [TCNP]<sub>2</sub><sup>2−</sup>. 2-Electron 8-Center Bonding
Published 2009“…The reaction of Cr(C<sub>6</sub>H<sub>6</sub>)<sub>2</sub> and 1,2,4,5-tetracyanopyrazine (TCNP) forms [Cr(C<sub>6</sub>H<sub>6</sub>)<sub>2</sub>][TCNP], and TCNP is reduced and forms the eclipsed π-[TCNP]<sub>2</sub><sup>2−</sup> dimer. …”
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30788
Mechanism of Cyanine5 to Cyanine3 Photoconversion and Its Application for High-Density Single-Particle Tracking in a Living Cell
Published 2021“…However, recent observations that blueshifted derivatives of Cy dyes are formed via photoconversion have raised concerns as to the potential artifacts in multicolor imaging. …”
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30789
Covalent Bonding and Atomic-Level Plasticity Increase Adhesion in Silicon–Diamond Nanocontacts
Published 2019“…First, covalent bonds formed across the interface, where the number of bonds formed was affected by the hydrogen termination of the substrate, the tip roughness, the applied stress, and the stochastic nature of bond formation. …”
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30790
A New Mode of Operation of Pd-NHC Systems Studied in a Catalytic Mizoroki–Heck Reaction
Published 2017“…Metal complexes bearing N-heterocyclic carbene (NHC) ligands are typically considered the system of choice for homogeneous catalysis with well-defined molecular active species due to their stable metal–ligand framework. A detailed study involving 19 different Pd-NHC complexes with imidazolium, benzimidazolium, and triazolium ligands has been carried out in the present work and revealed a new mode of operation of metal-NHC systems. …”
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30791
The reconstruction of an ancestral cluster
Published 2011“…A complex duplication in rodent genomes, involving subfamilies OR3A, OR1P, and OR1A, is marked with a rectangle. …”
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30792
Engineering 3D Cortical Spheroids for an <i>In Vitro</i> Ischemic Stroke Model
Published 2021“…Interestingly, the spheroids formed on the ULA surface exhibited striking aggregation dynamics involving active cell–substrate interactions, whereas those formed on the agarose surface aggregated passively by the convective flow of the media. …”
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30793
Engineering 3D Cortical Spheroids for an <i>In Vitro</i> Ischemic Stroke Model
Published 2021“…Interestingly, the spheroids formed on the ULA surface exhibited striking aggregation dynamics involving active cell–substrate interactions, whereas those formed on the agarose surface aggregated passively by the convective flow of the media. …”
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30794
Arbuscular-Mycorrhizal Networks Inhibit <em>Eucalyptus tetrodonta</em> Seedlings in Rain Forest Soil Microcosms
Published 2013“…Because the ashbed effect might involve disruption of common mycorrhizal networks, we hypothesized that in the absence of fire, intact rain forest arbuscular mycorrhizal (AM) networks inhibit <i>E. tetrodonta</i> seedlings. …”
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30795
Contingency in the convergent evolution of a regulatory network: Dosage compensation in <i>Drosophila</i>
Published 2019“…In particular, we take advantage of independently formed neo-sex chromosomes in <i>Drosophila</i> species that have evolved dosage compensation by co-opting the dosage-compensation male-specific lethal (MSL) complex to study the mutational paths that have led to the acquisition of hundreds of novel binding sites for the MSL complex in different species. …”
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30796
Functional Diversification within a Predatory Species Flock
Published 2013“…Moreover, this lineage appears to have independently evolved away from piscivory multiple times and derived forms are highly specialized morphologically and functionally relative to ancestral states. …”
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30797
Model of origin and evolution of archaic protein biosynthesis.
Published 2013“…We assume that these primordial enzymes were originally peptides of less than 60 amino acid residues that emerged from a pool of small peptides (some of them ∼ 25 residues in length and loop-forming) through non-specific condensation reactions. …”
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30798
Vulnerability-Based Critical Neurons, Synapses, and Pathways in the <i>Caenorhabditis elegans</i> Connectome
Published 2016“…Yet it remains unclear how nervous systems evolved highly efficient networks with near optimal sharing of pathways that yet produce multiple distinct behaviors to reach the organism’s goals. …”
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30799
Impact of <i>in vitro</i> passaging on the <i>C</i>. <i>trachomatis</i> growth kinetics.
Published 2015“…Cells grown in the same conditions were infected at a MOI of 1, and cell scrapings were collected over time after infection for analysis of inclusion-forming units (IFUs). The black line represents the evolved CT135-negative D/CS637/11 strain, whereas the grey line represents the ancestor CT135-positive strain. …”
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30800
Enhanced Metal Ion Selectivity of 2,9-Di-(pyrid-2-yl)-1,10-phenanthroline and Its Use as a Fluorescent Sensor for Cadmium(II)
Published 2008“…The metal ion complexing properties of the ligand DPP (2,9-di-(pyrid-2-yl)-1,10-phenanthroline) were studied by crystallography, fluorimetry, and UV−visible spectroscopy. Because DPP forms five-membered chelate rings, it will favor complexation with metal ions of an ionic radius close to 1.0 Å. …”