Non-covalent interactions between Akt1/Akt2-IN-1 (ball stick) and the AKT2 protein as predicted by molecular docking analyses. за авторством Sadia Afrin Runa (22504971)

“...<b>(b)</b> In the Y265N mutant, interactions involve Pi–anion bonding with GLU236, Pi-sulfur interactions with LYS277, and Pi-alkyl contacts with GLU279, GLU315, PHE238, PHE163, LYS277, VAL166, and MET282, and Pi-Sigma interaction with GLU315. ...”

Covalent Bonding and Atomic-Level Plasticity Increase Adhesion in Silicon–Diamond Nanocontacts за авторством Zachary B. Milne (7507097)

“...First, covalent bonds formed across the interface, where the number of bonds formed was affected by the hydrogen termination of the substrate, the tip roughness, the applied stress, and the stochastic nature of bond formation. ...”

Lewis Acid Catalyzed Three-Component Hetero-Diels−Alder (Povarov) Reaction of <i>N</i>-Arylimines with Strained Norbornene-Derived Dienophiles за авторством Chris D. Smith (2096089)

“...These observations may be rationalized by two competing mechanistic models, involving either a concerted asynchronous [4 + 2]-like mechanism or a stepwise mechanism....”

Efficient Non-Viral Reprogramming of Myoblasts to Stemness with a Single Small Molecule to Generate Cardiac Progenitor Cells за авторством Zeeshan Pasha (209560)

“...<div><p>The current protocols for generation of induced pluripotent stem (iPS) cells involve genome integrating viral vectors which may induce tumorgenesis. ...”

Space-time distribution of manganese ore deposits along the southern margin of the South China Block, in the context of Palaeo-Tethyan evolution за авторством Fangge Chen (3996392)

“...The carbonate C–O isotope and ore trace element composition data suggest that ore-forming fluids were dominated by seafloor water with involvement of magmatic hydrothermal fluids and organic matter as well. ...”

The activity of gluconeogenesis enzymes. за авторством Jyotsana Singhal (327563)

“...The method is based on a coupled enzyme reaction in which glucose formed is reacted with glucose oxidase and peroxidase and the quinoneimine formed is a colored product and its formation can be followed spectrophotometrically at 510 nm....”

The Tetracyanopyrazinide Dimer Dianion, [TCNP]₂²⁻. 2-Electron 8-Center Bonding за авторством Juan J. Novoa (1510171)

“...The reaction of Cr(C₆H₆)₂ and 1,2,4,5-tetracyanopyrazine (TCNP) forms [Cr(C₆H₆)₂][TCNP], and TCNP is reduced and forms the eclipsed π-[TCNP]₂²⁻ dimer. ...”

Mechanism of Cyanine5 to Cyanine3 Photoconversion and Its Application for High-Density Single-Particle Tracking in a Living Cell за авторством Yoonjung Cho (2736640)

“...However, recent observations that blueshifted derivatives of Cy dyes are formed via photoconversion have raised concerns as to the potential artifacts in multicolor imaging. ...”

Covalent Bonding and Atomic-Level Plasticity Increase Adhesion in Silicon–Diamond Nanocontacts за авторством Zachary B. Milne (7507097)

“...First, covalent bonds formed across the interface, where the number of bonds formed was affected by the hydrogen termination of the substrate, the tip roughness, the applied stress, and the stochastic nature of bond formation. ...”

A New Mode of Operation of Pd-NHC Systems Studied in a Catalytic Mizoroki–Heck Reaction за авторством Alexander V. Astakhov (1450873)

“...Metal complexes bearing N-heterocyclic carbene (NHC) ligands are typically considered the system of choice for homogeneous catalysis with well-defined molecular active species due to their stable metal–ligand framework. A detailed study involving 19 different Pd-NHC complexes with imidazolium, benzimidazolium, and triazolium ligands has been carried out in the present work and revealed a new mode of operation of metal-NHC systems. ...”

The reconstruction of an ancestral cluster за авторством Ronny Aloni (24421)

“...A complex duplication in rodent genomes, involving subfamilies OR3A, OR1P, and OR1A, is marked with a rectangle. ...”

Engineering 3D Cortical Spheroids for an <i>In Vitro</i> Ischemic Stroke Model за авторством Eunmin Ko (11152536)

“...Interestingly, the spheroids formed on the ULA surface exhibited striking aggregation dynamics involving active cell–substrate interactions, whereas those formed on the agarose surface aggregated passively by the convective flow of the media. ...”

Engineering 3D Cortical Spheroids for an <i>In Vitro</i> Ischemic Stroke Model за авторством Eunmin Ko (11152536)

“...Interestingly, the spheroids formed on the ULA surface exhibited striking aggregation dynamics involving active cell–substrate interactions, whereas those formed on the agarose surface aggregated passively by the convective flow of the media. ...”

Arbuscular-Mycorrhizal Networks Inhibit <em>Eucalyptus tetrodonta</em> Seedlings in Rain Forest Soil Microcosms за авторством David P. Janos (382967)

“...Because the ashbed effect might involve disruption of common mycorrhizal networks, we hypothesized that in the absence of fire, intact rain forest arbuscular mycorrhizal (AM) networks inhibit <i>E. tetrodonta</i> seedlings. ...”

Visualization 2 (Movie2.gif) за авторством Anne Sentenac (766155)

“...<p>zoom on the dynamics of paxillin nanoclusters--</p> <p><br></p> <p>Zoom on the paxillin nanoclusters dynamics during 1.2 second. 1000 speckled images were recorded every 1.2ms. The super-resolved images were formed from sequential stacks of 100 speckled images. ...”

Contingency in the convergent evolution of a regulatory network: Dosage compensation in <i>Drosophila</i> за авторством Christopher Ellison (87115)

“...In particular, we take advantage of independently formed neo-sex chromosomes in <i>Drosophila</i> species that have evolved dosage compensation by co-opting the dosage-compensation male-specific lethal (MSL) complex to study the mutational paths that have led to the acquisition of hundreds of novel binding sites for the MSL complex in different species. ...”

Functional Diversification within a Predatory Species Flock за авторством Edward D. Burress (488375)

“...Moreover, this lineage appears to have independently evolved away from piscivory multiple times and derived forms are highly specialized morphologically and functionally relative to ancestral states. ...”

Model of origin and evolution of archaic protein biosynthesis. за авторством Gustavo Caetano-Anollés (65405)

“...We assume that these primordial enzymes were originally peptides of less than 60 amino acid residues that emerged from a pool of small peptides (some of them ∼ 25 residues in length and loop-forming) through non-specific condensation reactions. ...”

Impact of <i>in vitro</i> passaging on the <i>C</i>. <i>trachomatis</i> growth kinetics. за авторством Vítor Borges (774790)

“...Cells grown in the same conditions were infected at a MOI of 1, and cell scrapings were collected over time after infection for analysis of inclusion-forming units (IFUs). The black line represents the evolved CT135-negative D/CS637/11 strain, whereas the grey line represents the ancestor CT135-positive strain. ...”

Enhanced Metal Ion Selectivity of 2,9-Di-(pyrid-2-yl)-1,10-phenanthroline and Its Use as a Fluorescent Sensor for Cadmium(II) за авторством Gregory M. Cockrell (2006527)

“...The metal ion complexing properties of the ligand DPP (2,9-di-(pyrid-2-yl)-1,10-phenanthroline) were studied by crystallography, fluorimetry, and UV−visible spectroscopy. Because DPP forms five-membered chelate rings, it will favor complexation with metal ions of an ionic radius close to 1.0 Å. ...”