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Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain
Udgivet 2018“...It has been shown that hDAT and other members of the monoamine transporter family exist in oligomeric forms at the plasma membrane. Several residues are known to be involved in oligomerization, but interaction interfaces, oligomer orientation and the quarternary arrangement in the plasma membrane remain poorly understood. ...”
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ZEBOV trafficking involves early and late endosomes.
Udgivet 2013“...</b> HEK293T cells were made to express GFP or GFP-tagged forms of DN Rab5, DN Rab7 by plasmid transfection. ...”
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The 161 genes coding for proteins forming ionic channels or involved in neurotransmitter release.
Udgivet 2014“...</p><p>The 161 genes coding for proteins forming ionic channels or involved in neurotransmitter release....”
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Widespread Involvement of Acetylation in the Retinal Metabolism of Form-Deprivation Myopia in Guinea Pigs
Udgivet 2023“...Although the pathogenesis of myopia remains controversial, proteomic studies suggest that dysregulation of retinal metabolism is potentially involved in the pathology of myopia. Lysine acetylation of proteins plays a key role in regulating cellular metabolism, but little is known about its role in the form-deprived myopic retina. ...”
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Residues involved in forming H-bonds and hydrophobic contacts between the proteins and the ligands.
Udgivet 2021“...<p>Residues involved in forming H-bonds and hydrophobic contacts between the proteins and the ligands....”
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