Additions, Losses, and Rearrangements on the Evolutionary Route from a Reconstructed Ancestor to the Modern <em>Saccharomyces cerevisiae</em> Genome by Jonathan L. Gordon (212846)

“…We then inferred the series of rearrangement steps that led from this ancestor to the current <em>Saccharomyces cerevisiae</em> genome; relative to the ancestral genome we observe 73 inversions, 66 reciprocal translocations, and five translocations involving telomeres. Some fragile chromosomal sites were reused as evolutionary breakpoints multiple times. …”

Preparation and Crystallography of 1,2-Bis(chloromercurio)tetrafluorobenzene Adducts with Nitrobenzene and Nitrotoluenes by Andrey A. Yakovenko (1644979)

“…This indicates that supramolecular organization involving Hg nonbonded interactions in some cases will be helpful to produce acentric structures of polar molecules by incorporating them in co-crystals with <b>II</b>. …”

Dual embryonic origin of maxillary lateral incisors: clinical implications in patients with cleft lip and palate by Daniela Gamba Garib (4660036)

“…<div><p>Introduction:Cleft lip and palate are craniofacial anomalies highly prevalent in the overall population. In oral clefts involving the alveolar ridge, variations of number, shape, size and position are observed in maxillary lateral incisors. …”

Alpine Tethys rift-related OIB-type magmatism preserved on Elba Island (Northern Apennines, Italy) by Federico Lucci (3243132)

“…Calamita promontory (SE Elba Island, Italy) are postulated to have been formed during a Middle to Upper Triassic mafic magmatic event that intruded the Permo-Triassic sedimentary succession deposited on the thinned Adria paleo-margin during the break-up of Pangea. …”

Table_1_Case Report: A Novel CACNA1A Mutation Caused Flunarizine-Responsive Type 2 Episodic Ataxia and Hemiplegic Migraine With Abnormal MRI of Cerebral White Matter.DOCX by Xiaoqiu Yuan (9624123)

“…Sporadic hemiplegic migraine (SHM) is another rare disease involving CACNA1A variants, which seldom coexists with EA2. …”

MAPPING PRIMARY SCHOOL LUNCH CATERING PROVISIONI<b>N</b>G IN ENGLAND by Melanie Southerden (20974189)

“…Despite their potential, school lunches are often undermined by cost-efficiency pressures, such as the challenge of providing nutritious meals for just £2.53 per child. Growing corporate involvement in school catering coincides with the displacement of Minimally Processed Foods (MPF) in favour of highly processed alternatives, worsening the issue. …”

Integrated Digital Microfluidic Platform for Colorimetric Sensing of Nitrite by Zhen Gu (314816)

“…This integrated DMF platform can be a promising new tool for a wide range of applications involving step-by-step solution mixing and optical detection in environmental monitoring, food safety analysis, and point-of-care testing.…”

Reactions of a Hydroxy Phosphonite Ligand in the Coordination Sphere of Rhodium(I) by Detlef Selent (1783498)

“…The first is based on a transesterification reaction involving 2 equiv of the hydroxy phosphonite, giving rise to a substituted biphenol and a symmetric bidentate phosphorus ligand of a heretofore uncertain structure. …”

Mechanism of Alcohol Oxidation Mediated by Copper(II) and Nitroxyl Radicals by Bradford L. Ryland (1759060)

“…A bimolecular pathway involving hydrogen-atom-transfer from a Cu^II–alkoxide to a nitroxyl radical is higher in energy than hydrogen transfer from a Cu^II–alkoxide to a coordinated nitroxyl species. …”

HP1 Recruitment in the Absence of Argonaute Proteins in <em>Drosophila</em> by Nellie Moshkovich (117205)

“…Previous studies in <em>Drosophila melanogaster</em> have suggested the involvement of both the <em>AGO2</em>-dependent endogenous small interfering RNA (endo-siRNA) as well as Piwi-interacting RNA (piRNA) silencing pathways. …”

Image_4_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.pdf by Isabel M. García-Guillén (10147727)

“…The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. …”

Novel Combretastatin-2-aminoimidazole Analogues as Potent Tubulin Assembly Inhibitors: Exploration of Unique Pharmacophoric Impact of Bridging Skeleton and Aryl Moiety by Vikas Chaudhary (649962)

“…Combretastatin A-4 (CA-4) in phosphate and serine pro-drug forms is under phase II clinical trials. With our interest of discovering CA-4 inspired new chemical entities, a novel series of 4,5-diaryl-2-aminoimidazole analogues of the compound was designed and synthesized by an efficient and diversity feasible route involving atom economical arene C–H bond arylation. …”

Image_3_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.pdf by Isabel M. García-Guillén (10147727)

“…The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. …”

Nucleophilic Degradation of a β-Diketiminato Ancillary by a Transient Scandium Hydride Intermediate by Korey D. Conroy (2339362)

“…The reactions involving LiAlH₄, along with labeling studies, helped to clarify the fragmentation pathway and account for the observed products.…”

Supplementary Material for: Molecular Cytogenetic Characterization of the Murine Melanoma Cell Lines S91 Clone M3 and B16-F1 with Variant B16-4A5 by Piaszinski K. (10155545)

“…This study revealed severely rearranged karyotypes with in parts similar imbalances for all 3 cell lines. Interestingly, they involve genes known to play major roles in human melanoma. …”

ICD and Interchromosomal Network (ICN) Models of Chromatin Organization in Mammalian Nuclei by Miguel R Branco (62457)

“…Functional associations that correlate with active and inactive states of transcription (2 and 4), including those involving clustering of active RNA polymerases on transcription factories, determine local arrangements within and between chromosomes, that influence the large-scale organization of chromosomes in each cell type. …”

Tetrabromobisphenol A Perturbs Erythropoiesis and Impairs Blood Circulation in Zebrafish Embryos by Shaochen Pang (257504)

“…Furthermore, our results demonstrated that PBI malformation induced by TBBPA resulted from effects on erythroid precursor cells, which might involve THR signaling in complex ways. These findings will improve the understanding of TBBPA-induced developmental toxicity in teleost.…”

Rich club structure in the macaque and human brain. by Alexandros Goulas (543989)

“…In the network representation, green and blue nodes represent rich club and non-rich club regions at level k respectively. Only connections involving at least one rich club region are depicted. …”

Dimerization of c-di-GMP-bound LapD^EAL. by Marcos V. A. S. Navarro (231597)

“…<p>(A) EAL domain dimerization. In both crystal forms obtained for LapD^EAL•c-di-GMP we observe symmetric dimerization between protomers involving helix α6 and the switch loop. …”

Gold-Catalyzed Intramolecular Allylic Amination of 2-Tosylaminophenylprop-1-en-3-ols. A Concise Synthesis of (±)-Angustureine by Prasath Kothandaraman (2047204)

“…The mechanism is suggested to involve activation of the alcohol substrate by the AuCl₃/AgSbF₆ catalyst. …”