Single-molecule magnetic tweezers (side view in x-z plane). حسب Rifka Vlijm (133750)

"…<b>C</b> When a nucleosome is formed from a histone octamer (orange) and DNA (black line), 146 bp (50 nm) of DNA is wrapped in 1.7 turns. …"

Impact of a modified implant macrogeometry on biomechanical parameters and bone-related markers in rats حسب Mounir Colares MUSSI (15377557)

"…Calcein and tetracycline fluorescent markers were used for analyzing newly formed bone at undecalcified sections of the tibial implants. …"

LPS structure comparison of <i>E</i>. <i>coli</i> strains W3110, HW001, HW002, WBB06, HWB01 and HWB02. حسب Biwen Wang (841544)

"…The enzymes WaaC, WaaF, LpxM and LpxE are shown in res with arrows indicating their functional domains, and the groups removed by these enzymes are shown in blue. Expression of <i>lpxE</i> in W3110 forms the strain HW001 that synthesizes PS-MPLA, and deletion of <i>lpxM</i> in HW001 forms the strain HW002 that synthesizes PS-pentaacyl-MPLA. …"

Activation of the VP16 promoter in sensory neurons during acute infection. حسب Richard L. Thompson (373730)

"…At regions at the edge of the plaques formed by 17-0pZ563gJ cells expressing b-gal (blue) with little or no evidence of viral protein expression were evident (arrow). …"

Nest Etiquette—Where Ants Go When Nature Calls حسب Tomer J. Czaczkes (137030)

"…After two months, 1–4 well defined dark patches, the colour of the sucrose solution, formed within each of the plaster nests. These patches never contained other waste material such as uneaten food items, or nestmate corpses. …"

Changes to DPPC Domain Structure in the Presence of Carbon Nanoparticles حسب Alan J. Sheridan (4678360)

"…DPPC (dipalmitoylphosphatidylcholine) is a disaturated lipid capable of forming closely packed monolayers at the air–liquid interface of the lung and allows the surface tension within the alveoli to reduce to almost zero and thus prevent alveolar collapse. …"

Multicomponent Assembly and Diversification of Novel Heterocyclic Scaffolds Derived from 2-Arylpiperidines حسب Simon Hardy (1555174)

"…A collection of structurally diverse, polyheterocyclic scaffolds comprising a 2-arylpiperidine subunit were synthesized using a Mannich-type multicomponent assembly process, followed by appropriately sequenced ring-forming reactions. An improved procedure for removal of <i>N</i>-4-pentenoyl groups was developed; one-pot sequences for tandem urea/thiourea formation and cyclization and tandem enolate arylation/alkylation were discovered. …"

Multicomponent Assembly and Diversification of Novel Heterocyclic Scaffolds Derived from 2-Arylpiperidines حسب Simon Hardy (1555174)

"…A collection of structurally diverse, polyheterocyclic scaffolds comprising a 2-arylpiperidine subunit were synthesized using a Mannich-type multicomponent assembly process, followed by appropriately sequenced ring-forming reactions. An improved procedure for removal of <i>N</i>-4-pentenoyl groups was developed; one-pot sequences for tandem urea/thiourea formation and cyclization and tandem enolate arylation/alkylation were discovered. …"

Model for repair of Cr-DNA lesions by Tdp1-Pnk1 and Rad16-Swi10 (XPF-ERCC1) pathways. حسب Abantika Ganguly (2126932)

"…In the model shown, this cleavage occurs at an seDSB that is formed by replication fork collapse. After removal of Cr-DNA lesion, the seDSB is repaired by SCR requiring key HR proteins such as MRN-Ctp1 and Rad51, followed by resolution of the Holliday junction or D-loop by Mus81-Eme1 endonuclease.…"

Predicted protein conformational changes. حسب Jeffrey R. Kugelman (297042)

"…<p>Locations of the observed mutations within the structures of EBOV proteins: a) GP truncations – occur right after a disordered region in the crystal structure. The truncation also removes the ends of the trimer (in red). b) GP_1,2 – residue E47 (vdW spheres) is near the top of the trimer and, in the X-ray crystal structure (3CSY), makes no interactions with other side chains. c) VP24 – residue K163 forms a tight salt-bridge with D104 on another helix near an undetermined loop in the X-ray structure.…"

Copper-Mediated Formally Dehydrative Biaryl Coupling of Azine <i>N</i>‑Oxides and Oxazoles حسب Riko Odani (1651888)

"…A copper-mediated formally dehydrative biaryl coupling of azine <i>N</i>-oxides and oxazoles has been developed. The C–C bond-forming process proceeds, accompanied by the removal of the oxygen atom from the azine core, to directly afford the azine–oxazole biaryl linkage. …"

A comparison of experimental and simulated profiles demonstrates that ECM is sufficient to maintain the bent profile of the tissue. حسب Ali Nematbakhsh (4039544)

"…(A’) Computational model after the bent profile of the wing disc is formed with higher levels of basal actomyosin contractility. …"

Data_Sheet_5_Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog... حسب Hana Dvořáková (537198)

"…<p>Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very narrow substrate specificity and after processing it was less effective toward protein substrates when compared to TrCB1.1. …"

Data_Sheet_6_Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog... حسب Hana Dvořáková (537198)

"…<p>Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very narrow substrate specificity and after processing it was less effective toward protein substrates when compared to TrCB1.1. …"

Data_Sheet_1_Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog... حسب Hana Dvořáková (537198)

"…<p>Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very narrow substrate specificity and after processing it was less effective toward protein substrates when compared to TrCB1.1. …"

Versatility of Two Diimidazole Building Blocks in Coordination-Driven Self-Assembly حسب Bijan Roy (1525411)

"…Surprisingly, the macrocycle (<b>9</b>) involving <b>L2</b> is found to exist in more than one conformation at room temperature. …"

Data_Sheet_4_Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog... حسب Hana Dvořáková (537198)

"…<p>Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very narrow substrate specificity and after processing it was less effective toward protein substrates when compared to TrCB1.1. …"

Versatility of Two Diimidazole Building Blocks in Coordination-Driven Self-Assembly حسب Bijan Roy (1525411)

"…Surprisingly, the macrocycle (<b>9</b>) involving <b>L2</b> is found to exist in more than one conformation at room temperature. …"

Data_Sheet_3_Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog... حسب Hana Dvořáková (537198)

"…<p>Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very narrow substrate specificity and after processing it was less effective toward protein substrates when compared to TrCB1.1. …"

Data_Sheet_7_Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog... حسب Hana Dvořáková (537198)

"…<p>Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very narrow substrate specificity and after processing it was less effective toward protein substrates when compared to TrCB1.1. …"