Integrated Digital Microfluidic Platform for Colorimetric Sensing of Nitrite od Zhen Gu (314816)

“…This integrated DMF platform can be a promising new tool for a wide range of applications involving step-by-step solution mixing and optical detection in environmental monitoring, food safety analysis, and point-of-care testing.…”

Reactions of a Hydroxy Phosphonite Ligand in the Coordination Sphere of Rhodium(I) od Detlef Selent (1783498)

“…The first is based on a transesterification reaction involving 2 equiv of the hydroxy phosphonite, giving rise to a substituted biphenol and a symmetric bidentate phosphorus ligand of a heretofore uncertain structure. …”

Mechanism of Alcohol Oxidation Mediated by Copper(II) and Nitroxyl Radicals od Bradford L. Ryland (1759060)

“…A bimolecular pathway involving hydrogen-atom-transfer from a Cu^II–alkoxide to a nitroxyl radical is higher in energy than hydrogen transfer from a Cu^II–alkoxide to a coordinated nitroxyl species. …”

HP1 Recruitment in the Absence of Argonaute Proteins in <em>Drosophila</em> od Nellie Moshkovich (117205)

“…Previous studies in <em>Drosophila melanogaster</em> have suggested the involvement of both the <em>AGO2</em>-dependent endogenous small interfering RNA (endo-siRNA) as well as Piwi-interacting RNA (piRNA) silencing pathways. …”

Image_4_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.pdf od Isabel M. García-Guillén (10147727)

“…The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. …”

Novel Combretastatin-2-aminoimidazole Analogues as Potent Tubulin Assembly Inhibitors: Exploration of Unique Pharmacophoric Impact of Bridging Skeleton and Aryl Moiety od Vikas Chaudhary (649962)

“…Combretastatin A-4 (CA-4) in phosphate and serine pro-drug forms is under phase II clinical trials. With our interest of discovering CA-4 inspired new chemical entities, a novel series of 4,5-diaryl-2-aminoimidazole analogues of the compound was designed and synthesized by an efficient and diversity feasible route involving atom economical arene C–H bond arylation. …”

Image_3_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.pdf od Isabel M. García-Guillén (10147727)

“…The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. …”

Nucleophilic Degradation of a β-Diketiminato Ancillary by a Transient Scandium Hydride Intermediate od Korey D. Conroy (2339362)

“…The reactions involving LiAlH₄, along with labeling studies, helped to clarify the fragmentation pathway and account for the observed products.…”

Supplementary Material for: Molecular Cytogenetic Characterization of the Murine Melanoma Cell Lines S91 Clone M3 and B16-F1 with Variant B16-4A5 od Piaszinski K. (10155545)

“…This study revealed severely rearranged karyotypes with in parts similar imbalances for all 3 cell lines. Interestingly, they involve genes known to play major roles in human melanoma. …”

ICD and Interchromosomal Network (ICN) Models of Chromatin Organization in Mammalian Nuclei od Miguel R Branco (62457)

“…Functional associations that correlate with active and inactive states of transcription (2 and 4), including those involving clustering of active RNA polymerases on transcription factories, determine local arrangements within and between chromosomes, that influence the large-scale organization of chromosomes in each cell type. …”

Tetrabromobisphenol A Perturbs Erythropoiesis and Impairs Blood Circulation in Zebrafish Embryos od Shaochen Pang (257504)

“…Furthermore, our results demonstrated that PBI malformation induced by TBBPA resulted from effects on erythroid precursor cells, which might involve THR signaling in complex ways. These findings will improve the understanding of TBBPA-induced developmental toxicity in teleost.…”

Rich club structure in the macaque and human brain. od Alexandros Goulas (543989)

“…In the network representation, green and blue nodes represent rich club and non-rich club regions at level k respectively. Only connections involving at least one rich club region are depicted. …”

Dimerization of c-di-GMP-bound LapD^EAL. od Marcos V. A. S. Navarro (231597)

“…<p>(A) EAL domain dimerization. In both crystal forms obtained for LapD^EAL•c-di-GMP we observe symmetric dimerization between protomers involving helix α6 and the switch loop. …”

Gold-Catalyzed Intramolecular Allylic Amination of 2-Tosylaminophenylprop-1-en-3-ols. A Concise Synthesis of (±)-Angustureine od Prasath Kothandaraman (2047204)

“…The mechanism is suggested to involve activation of the alcohol substrate by the AuCl₃/AgSbF₆ catalyst. …”

Fuzzy Association of an Intrinsically Disordered Protein with Acidic Membranes od Alan Hicks (9748246)

“…Many physiological and pathophysiological processes, including <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>) cell division, may involve fuzzy membrane association by proteins via intrinsically disordered regions. …”

Tetrabromobisphenol A Perturbs Erythropoiesis and Impairs Blood Circulation in Zebrafish Embryos od Shaochen Pang (257504)

“…Furthermore, our results demonstrated that PBI malformation induced by TBBPA resulted from effects on erythroid precursor cells, which might involve THR signaling in complex ways. These findings will improve the understanding of TBBPA-induced developmental toxicity in teleost.…”

Supplementary Material for: Reciprocal Antagonism between MicroRNA-138 and SIRT1 and Its Implications for the Angiogenesis of Endothelial Cells od Wang S. (3116754)

“…These results demonstrated that the circuitry involving miR-138 and SIRT1 may participate in vascular homeostasis and also offered the possibility of identifying a new approach in the treatment of angiogenic diseases.…”

Schematic of the functional prototypic HBV ε signal od Frederic C. Girard (30969)

“…Binding is followed by structural rearrangements to obtain a priming competent complex (,). This should involve residues G, C and U (open circle), as they are not P accessible upon initial binding and have been proposed () to be part of a network of anchor residues, enabling precise positioning of P over the initiation site (see text).…”

<i>trans</i>-Pyridyl and Naphthyridyl Cinnamides as Alternatives for Urea in Complexation of Carboxylic Acid and Formation of Water-Templated Assemblies in the Solid State od Kumaresh Ghosh (536184)

“…The experimental results have been rationalized with an accompanying theoretical study involving density functional calculations on the structure and the relative energies of different rotamers of the host systems as well as the binding energy of the complexes formed with <i>trans-</i>cinnamic acid. …”

Video_1_Case Report: A Novel CACNA1A Mutation Caused Flunarizine-Responsive Type 2 Episodic Ataxia and Hemiplegic Migraine With Abnormal MRI of Cerebral White Matter.MP4 od Xiaoqiu Yuan (9624123)

“…Sporadic hemiplegic migraine (SHM) is another rare disease involving CACNA1A variants, which seldom coexists with EA2. …”