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28161
Heterocyclic Derivative Syntheses by Palladium-Catalyzed Oxidative Cyclization−Alkoxycarbonylation of Substituted γ-Oxoalkynes
Publicado 2005“...It has been found that cyclopentenone, dihydropyridinone, and tetrahydropyridinedione derivatives, formed when the reaction is carried out at higher temperature and for a longer time, can also be selectively obtained through an acid treatment of tetrahydrofuran and oxazoline derivatives involving an unusual rearrangement. ...”
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28162
<i>trans</i>-Pyridyl and Naphthyridyl Cinnamides as Alternatives for Urea in Complexation of Carboxylic Acid and Formation of Water-Templated Assemblies in the Solid State
Publicado 2010“...The experimental results have been rationalized with an accompanying theoretical study involving density functional calculations on the structure and the relative energies of different rotamers of the host systems as well as the binding energy of the complexes formed with <i>trans-</i>cinnamic acid. ...”
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28163
Antineoplastic potential of the aqueous crude extract of Eugenia uniflora L. in human cervical cancer
Publicado 2022“...<div><p>Abstract Considering the high prevalence of human cervical cancer and the adverse effects of the available treatments, it is important to develop studies involving plants. Eugenia uniflora L. is a Brazilian native plant widely used in folk medicine and some biological effects have already been described. ...”
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28164
Fuzzy Association of an Intrinsically Disordered Protein with Acidic Membranes
Publicado 2020“...Many physiological and pathophysiological processes, including <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>) cell division, may involve fuzzy membrane association by proteins via intrinsically disordered regions. ...”
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28165
DataSheet1_Comparative molecular dynamics simulations of pathogenic and non-pathogenic huntingtin protein monomers and dimers.pdf
Publicado 2023“...Dimerization can proceed via different modes, where those involving the N-terminal headpiece bury more hydrophobic residues and are thus more stable. ...”
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28166
Data_Sheet_1_Development and Testing of Force Field Parameters for Phenylalanine and Tyrosine Derivatives.PDF
Publicado 2020“...This work will provide theoretical aid for drug design involving unnatural amino acids.</p>...”
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28167
Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in <i>Caenorhabditis elegans</i>
Publicado 2013“...Our results reveal that the Sup35 prion domain exhibits prion-like properties when expressed in the multicellular organism <i>C. elegans</i> and adapts to different requirements for propagation that involve the autophagy-lysosome pathway to transmit cytosolic aggregation-prone proteins between tissues....”
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28168
<i>trans</i>-Pyridyl and Naphthyridyl Cinnamides as Alternatives for Urea in Complexation of Carboxylic Acid and Formation of Water-Templated Assemblies in the Solid State
Publicado 2010“...The experimental results have been rationalized with an accompanying theoretical study involving density functional calculations on the structure and the relative energies of different rotamers of the host systems as well as the binding energy of the complexes formed with <i>trans-</i>cinnamic acid. ...”
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28169
Gold-Catalyzed Intramolecular Allylic Amination of 2-Tosylaminophenylprop-1-en-3-ols. A Concise Synthesis of (±)-Angustureine
Publicado 2009“...The mechanism is suggested to involve activation of the alcohol substrate by the AuCl<sub>3</sub>/AgSbF<sub>6</sub> catalyst. ...”
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28170
Table_3_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.xlsx
Publicado 2021“...The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. ...”
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28171
Tetrabromobisphenol A Perturbs Erythropoiesis and Impairs Blood Circulation in Zebrafish Embryos
Publicado 2020“...Furthermore, our results demonstrated that PBI malformation induced by TBBPA resulted from effects on erythroid precursor cells, which might involve THR signaling in complex ways. These findings will improve the understanding of TBBPA-induced developmental toxicity in teleost....”
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28172
Data from: Olden and Bach. 2025. Social media facilitates the widespread exchange of ornamental aquarium organisms among hobbyists. Management of Biological Invasions.
Publicado 2025“...The survey contained a series of closed, and predominantly multi-select, questions where hobbyists were asked about their aquarism behaviors, including years of experience, types of organisms owned, activities involving the breeding and/or peer-to-peer transaction (buy, sell, trade, gift) of organisms, and actions associated with unwanted organisms. ...”
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28173
GEMINI: Integrative Exploration of Genetic Variation and Genome Annotations
Publicado 2013“...We demonstrate GEMINI's utility for exploring variation in personal genomes and family based genetic studies, and illustrate its ability to scale to studies involving thousands of human samples. GEMINI is designed for reproducibility and flexibility and our goal is to provide researchers with a standard framework for medical genomics....”
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28174
Gold-Catalyzed Intramolecular Allylic Amination of 2-Tosylaminophenylprop-1-en-3-ols. A Concise Synthesis of (±)-Angustureine
Publicado 2009“...The mechanism is suggested to involve activation of the alcohol substrate by the AuCl<sub>3</sub>/AgSbF<sub>6</sub> catalyst. ...”
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28175
The gene regulatory network for galactose utilization (redrawn from Bennett <i>et al.</i> (2008) [<b>12</b>]).
Publicado 2013“...According to sensitivity analysis, the interaction loops involving GAL4p dimerization (the dotted lines) can be eliminated from the original model to create a reduced model....”
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28176
PPRV IHC on sections of facial epithelial tissue. a)
Publicado 2013“...Evidence of advanced epithelial and proprial infection involving a mixed population of inflammatory and epithelial cells around an exocrine gland (arrows). ...”
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28177
Data_Sheet_1_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.PDF
Publicado 2021“...The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. ...”
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28178
Questionnaire: Discrimination and Mental Wellbeing among Sexual and Gender Minority Students in German Higher Education
Publicado 2024“...</p><p dir="ltr">The study was conducted as a cross-sectional survey involving 357 participants from eighty-six higher education institutions. ...”
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28179
Tetrabromobisphenol A Perturbs Erythropoiesis and Impairs Blood Circulation in Zebrafish Embryos
Publicado 2020“...Furthermore, our results demonstrated that PBI malformation induced by TBBPA resulted from effects on erythroid precursor cells, which might involve THR signaling in complex ways. These findings will improve the understanding of TBBPA-induced developmental toxicity in teleost....”
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28180
The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition. (1SNG)
Publicado 2016“...An undesirable result of this conformational flexibility is that most inhibitory serpins are heat sensitive, forming inactive polymers at elevated temperatures. ...”