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revolves. » evolves. (Expand Search), resolves. (Expand Search), evolved. (Expand Search)
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Activation of NRF2 by dexamethasone in ataxia telangiectasia cells involves KEAP1 inhibition but not the inhibition of p38
Published 2019“…Neither AKT nor ERK1/2, known to be NRF2-activating kinases, were found to be activated upon Dexamethasone treatment, thus excluding their involvement in the transcription factor nuclear shift. …”
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A Novel <i>Trypanosoma cruzi</i> Protein Associated to the Flagellar Pocket of Replicative Stages and Involved in Parasite Growth
Published 2015“…The reduced endocytic capacity of TCLP 1-over-expressors likely underlies (at least in part) this growth phenotype. TCLP 1 is involved in the uptake of extracellular macromolecules required for nutrition and hence in <i>T</i>. …”
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Table_1_The Voltage-Dependent Deactivation of the KvAP Channel Involves the Breakage of Its S4 Helix.XLSX
Published 2020“…Each subunit of these tetrameric channels is composed of six transmembrane helices, of which the anti-parallel helix bundle S1-S4 constitutes the voltage-sensor domain (VSD) and S5-S6 forms the pore domain. Here, using 82 molecular dynamics (MD) simulations involving 266 replicated VSDs, we report novel responses of the archaebacterial potassium channel KvAP to membrane polarization. …”
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<i>Trypanosoma cruzi</i> surface mucins are involved in the attachment to the <i>Triatoma infestans</i> rectal ampoule
Published 2019“…<i>cruzi</i> insect-dwelling forms, are involved in parasite attachment to the internal cuticle of the triatomine rectal ampoule, a critical step leading to its differentiation into mammal-infective forms. …”
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Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of <i>Trypanosoma cruzi</i>
Published 2016“…Moreover, heterozygous knockout cells presented a better efficiency in differentiation from epimastigote to metacyclic trypomastigote forms and metacyclic trypomastigote infection. Taken together, these findings indicate the involvement of TcRPA in the metacyclogenesis process and suggest that a delay in cell cycle progression could be linked with differentiation in <i>T</i>. …”
