Structural basis of mammalian glycan targeting by <i>Vibrio cholerae</i> cytolysin and biofilm proteins Dahkki Swastik De (4846885)

“…<i>Vibrio cholerae</i> cytolysin (VCC) is a secreted pore-forming toxin with a carboxy-terminal β-prism domain that targets complex <i>N</i>-glycans found on mammalian cell-surface proteins. …”

PTML Combinatorial Model of ChEMBL Compounds Assays for Multiple Types of Cancer Dahkki Harbil Bediaga (5813870)

“…These assays cover different combinations of <b>c</b>_<i>j</i> formed from >70 different biological activity parameters (<i>c</i>₀), >300 different drug targets (<i>c</i>₁), >230 cell lines (<i>c</i>₂), and 5 organisms of assay (<i>c</i>₃) or organisms of the target (<i>c</i>₄). …”

DataSheet1_Synthesis of C7/C8-cyclitols and C7N-aminocyclitols from maltose and X-ray crystal structure of Streptomyces coelicolor GlgEI V279S in a complex with an amylostatin GXG–... Dahkki Radhika Thanvi (13764460)

“…The Asp 394 nucleophile formed a bidentate hydrogen bond interaction with the exocyclic oxygen atoms (C(3)-OH and C(7)-OH) similar to the observed interactions with the Sco GlgEI-V279S in a complex with AGV (PDB:7MGY). …”

PTML Combinatorial Model of ChEMBL Compounds Assays for Multiple Types of Cancer Dahkki Harbil Bediaga (5813870)

“…These assays cover different combinations of <b>c</b>_<i>j</i> formed from >70 different biological activity parameters (<i>c</i>₀), >300 different drug targets (<i>c</i>₁), >230 cell lines (<i>c</i>₂), and 5 organisms of assay (<i>c</i>₃) or organisms of the target (<i>c</i>₄). …”

Oxidative <i>ortho</i>-C-N Fusion of Aniline by OsO₄. Isolation, Characterization of Oxo-Amido Osmium(VI) Complexes, and their Catalytic Activities for Oxidative C−C Bon... Dahkki Subhas Samanta (1469086)

“…In an unusual reaction of osmium(VIII) oxide with <i>p</i>-substituted aromatic amines (X-C₆H₄-NH₂, where X = Me, H, Cl) in heptane afforded the brown osmium(VI)-oxo complexes [OsO(L)₂] (<b>1a-c</b>, L = N-aryl-1,2-arylenediamide) in moderate yields. The ligand L is formed <i>in situ</i> via oxidative <i>ortho</i>-C-N fusion of arylamines. …”

DataSheet_2_Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain of the hERG1 Channel: Implications for a State-Dependent Blockade.pdf Dahkki Meruyert Kudaibergenova (9042995)

“…<p>Human-ether-a-go-go-related channel (hERG1) is the pore-forming domain of the delayed rectifier K⁺ channel in the heart which underlies the I_Kr current. …”

A Novel Cadmium Aminophosphonate:  X-ray Powder Diffraction Structure, Solid-State IR and NMR Spectroscopic Determination of the Fine Structure of the Organic Moieties Dahkki Ekaterina V. Bakhmutova-Albert (1855915)

“…Cadmium atoms are bridged by the chlorine atoms forming four-membered rings. The phosphorus atoms exhibit a tetrahedral coordination with two oxygen atoms bonded to the cadmium atoms with P−O distances of 1.503(10) and 1.504(10) Å. …”

DataSheet_1_Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain of the hERG1 Channel: Implications for a State-Dependent Blockade.zip Dahkki Meruyert Kudaibergenova (9042995)

“…<p>Human-ether-a-go-go-related channel (hERG1) is the pore-forming domain of the delayed rectifier K⁺ channel in the heart which underlies the I_Kr current. …”

PTML Combinatorial Model of ChEMBL Compounds Assays for Multiple Types of Cancer Dahkki Harbil Bediaga (5813870)

“…These assays cover different combinations of <b>c</b>_<i>j</i> formed from >70 different biological activity parameters (<i>c</i>₀), >300 different drug targets (<i>c</i>₁), >230 cell lines (<i>c</i>₂), and 5 organisms of assay (<i>c</i>₃) or organisms of the target (<i>c</i>₄). …”

From Exothermic to Endothermic Dehydrogenation – Interaction of Monoammoniate of Magnesium Amidoborane and Metal Hydrides Dahkki Yong Shen Chua (1798741)

“…Based on the calculated results, a reactant stabilization approach was proposed, which suggests that forming a stable reactant is an effective way of reducing the exothermicity of the dehydrogenation of metal amidoborane.…”

A Systematic Evaluation of Molecular Recognition Phenomena. 1. Interaction between Phosphates and Nucleotides with Hexaazamacrocyclic Ligands Containing <i>m</i>-Xylylic Spacers Dahkki Carmen Anda (2464216)

“…Ternary complexes are formed in aqueous solution as a result of hydrogen bond formation and Coulombic attraction between the host and the guest. …”

High Proton Conductivity in a Flexible, Cross-Linked, Ultramicroporous Magnesium Tetraphosphonate Hybrid Framework Dahkki Rosario M. P. Colodrero (2036560)

“…Its crystal structure, solved by Patterson-function direct methods from synchrotron powder X-ray diffraction, was characterized by a 3D pillared open framework containing cross-linked 1D channels filled with water and DMF. …”

From Exothermic to Endothermic Dehydrogenation – Interaction of Monoammoniate of Magnesium Amidoborane and Metal Hydrides Dahkki Yong Shen Chua (1798741)

“…Based on the calculated results, a reactant stabilization approach was proposed, which suggests that forming a stable reactant is an effective way of reducing the exothermicity of the dehydrogenation of metal amidoborane.…”

A wake-active locomotion circuit depolarizes a sleep-active neuron to switch on sleep Dahkki Elisabeth Maluck (8474331)

“…Wake-active wake-promoting neurons in turn shut down sleep-active neurons, thus forming a bipartite flip-flop switch. However, how sleep is switched on is unclear because it is not known how wakefulness is translated into sleep-active neuron depolarization when the system is set to sleep. …”

Structural basis of <i>Toxoplasma gondii</i> perforin-like protein 1 membrane interaction and activity during egress Dahkki Alfredo J. Guerra (2005315)

“…Apicomplexans are a phylum of intracellular protozoans that have evolved members of the membrane attack complex and perforin (MACPF) family of pore forming proteins to disrupt cellular membranes for traversing cells during tissue migration or egress from a replicative vacuole following intracellular reproduction. …”

PredAPP: Predicting Anti-Parasitic Peptides with Undersampling and Ensemble Approaches Dahkki Interdis Sci Comp Life Sci (7335308)

“…Then, nine groups of features and six ML algorithms were combined to generate 54 classifiers and the output of these classifiers formed 54 feature representations, and in each feature group, we selected the feature representation with best performance for classification. …”

A New Two-Dimensional Molybdenum(V) Nickel Phosphate Built Up of [H₁₈(Mo₁₆O₃₂)Ni₁₆(PO₄)₂₆(OH)₆(H<sub>2<... Dahkki Charlotte du Peloux (2711719)

“…The structure (orthorhombic, space group <i>Cccm</i>; <i>a</i> = 23.999(4), <i>b</i> = 36.595(6), <i>c</i> = 20.445(4) Å) was solved from single-crystal data. The framework structure of <b>1</b> consists of anionic inorganic sheets formed by the linkages of large polyoxomolybdate rings via nickel(II) octahedra. …”

Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs Carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots Dahkki Marianna Colasuonno (5982593)

“…In murine mesentery venules, the intravenous administration of 2.5 mg/kg of tPA-DPNs resolves almost 90% of the blood clots, whereas a similar dose of free tPA successfully recanalizes only about 40% of the treated vessels. …”

Table_2_In Situ X-Ray Tomography Imaging of Soil Water and Cyanobacteria From Biological Soil Crusts Undergoing Desiccation.DOCX Dahkki Estelle Couradeau (192890)

“…Biocrusts consist of an assemblage of mineral soil particles consolidated into a crust by microbial organic polymeric substances that are mainly produced by filamentous bundle-forming cyanobacteria, among which Microcoleus vaginatus is perhaps the most widespread. …”

Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs Carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots Dahkki Marianna Colasuonno (5982593)

“…In murine mesentery venules, the intravenous administration of 2.5 mg/kg of tPA-DPNs resolves almost 90% of the blood clots, whereas a similar dose of free tPA successfully recanalizes only about 40% of the treated vessels. …”