Showing 81 - 100 results of 1,608 for search 'hard is (((((evolves. OR evolves.) OR evolveddssdds.) OR resolvedd.) OR involved.) OR involves.)*', זמן שאילתה: 0.41s Refine Results
  1. 81

    Data_Sheet_1_Neuropsychiatric outcomes following strokes involving the cerebellum: a retrospective cohort study.pdf מאת Victoria A. Muller Ewald (16482201)

    יצא לאור 2023
    "...Introduction<p>Given the wide-ranging involvement of cerebellar activity in motor, cognitive, and affective functions, clinical outcomes resulting from cerebellar damage can be hard to predict. ..."
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    Involvement of Pazopanib and Sunitinib Aldehyde Reactive Metabolites in Toxicity and Drug–Drug Interactions <i>in Vitro</i> and in Patient Samples מאת Marie-Noëlle Paludetto (5683055)

    יצא לאור 2019
    "...However, the recent discovery of new reactive metabolites (RM) with aldehyde structures during pazopanib and sunitinib metabolism offers new perspectives for investigating their involvement in the toxicity of these two TKI. These hard electrophiles have a high reactivity potential toward proteins and are thought to be responsible for cytochrome P450 inactivation, drug–drug interactions (DDI), and liver toxicity. ..."
  4. 84

    Involvement of Pazopanib and Sunitinib Aldehyde Reactive Metabolites in Toxicity and Drug–Drug Interactions <i>in Vitro</i> and in Patient Samples מאת Marie-Noëlle Paludetto (5683055)

    יצא לאור 2019
    "...However, the recent discovery of new reactive metabolites (RM) with aldehyde structures during pazopanib and sunitinib metabolism offers new perspectives for investigating their involvement in the toxicity of these two TKI. These hard electrophiles have a high reactivity potential toward proteins and are thought to be responsible for cytochrome P450 inactivation, drug–drug interactions (DDI), and liver toxicity. ..."
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