Retrosynthesis report for the 10 best-ranked routes for IM-204 מאת Rodolfo Teixeira (14601323)

"...The project will thus benefit from an interdisciplinary domain, involving: - recent advances in biomass conversion for drug synthesis; - new developments in heterogeneous catalysis; - cutting-edge flow chemistry technologies (including synthesis and purification); - automation and machine learning. ..."

Data Sheet 3_Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems.pdf מאת Kosuke Sakaguchi (21249107)

"...Furthermore, the differentiated organoids specifically responded to a bitter compound, suggesting that pancreatic tuft cells may play a role in detecting potentially harmful chemicals. Finally, immunohistochemical analysis identified tuft cells in the non-human primate pancreas, supporting their involvement in sensing harmful compounds and regulating protective responses within the pancreas...."

Image1_CRISPR Detection and Research on Screening Mutant Gene TTN of Moyamoya Disease Family Based on Whole Exome Sequencing.TIF מאת Yilei Xiao (8814119)

"...We also analyzed mutation frequencies and used bioinformatic predictions to reveal mutation harmfulness, functions and probabilities of disease correlation, the results showed that rs771533925 and rs72677250 were likely harmful mutations with GO analyses indicating the involvement of TTN in a variety of biological processes related to MMD etiology. ..."

Image4_CRISPR Detection and Research on Screening Mutant Gene TTN of Moyamoya Disease Family Based on Whole Exome Sequencing.TIF מאת Yilei Xiao (8814119)

"...We also analyzed mutation frequencies and used bioinformatic predictions to reveal mutation harmfulness, functions and probabilities of disease correlation, the results showed that rs771533925 and rs72677250 were likely harmful mutations with GO analyses indicating the involvement of TTN in a variety of biological processes related to MMD etiology. ..."

DataSheet1_CRISPR Detection and Research on Screening Mutant Gene TTN of Moyamoya Disease Family Based on Whole Exome Sequencing.docx מאת Yilei Xiao (8814119)

"...We also analyzed mutation frequencies and used bioinformatic predictions to reveal mutation harmfulness, functions and probabilities of disease correlation, the results showed that rs771533925 and rs72677250 were likely harmful mutations with GO analyses indicating the involvement of TTN in a variety of biological processes related to MMD etiology. ..."

Data Sheet 1_Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems.pdf מאת Kosuke Sakaguchi (21249107)

"...Furthermore, the differentiated organoids specifically responded to a bitter compound, suggesting that pancreatic tuft cells may play a role in detecting potentially harmful chemicals. Finally, immunohistochemical analysis identified tuft cells in the non-human primate pancreas, supporting their involvement in sensing harmful compounds and regulating protective responses within the pancreas...."

Image2_CRISPR Detection and Research on Screening Mutant Gene TTN of Moyamoya Disease Family Based on Whole Exome Sequencing.TIF מאת Yilei Xiao (8814119)

"...We also analyzed mutation frequencies and used bioinformatic predictions to reveal mutation harmfulness, functions and probabilities of disease correlation, the results showed that rs771533925 and rs72677250 were likely harmful mutations with GO analyses indicating the involvement of TTN in a variety of biological processes related to MMD etiology. ..."

Image5_CRISPR Detection and Research on Screening Mutant Gene TTN of Moyamoya Disease Family Based on Whole Exome Sequencing.TIF מאת Yilei Xiao (8814119)

"...We also analyzed mutation frequencies and used bioinformatic predictions to reveal mutation harmfulness, functions and probabilities of disease correlation, the results showed that rs771533925 and rs72677250 were likely harmful mutations with GO analyses indicating the involvement of TTN in a variety of biological processes related to MMD etiology. ..."

Data Sheet 4_Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems.pdf מאת Kosuke Sakaguchi (21249107)

"...Furthermore, the differentiated organoids specifically responded to a bitter compound, suggesting that pancreatic tuft cells may play a role in detecting potentially harmful chemicals. Finally, immunohistochemical analysis identified tuft cells in the non-human primate pancreas, supporting their involvement in sensing harmful compounds and regulating protective responses within the pancreas...."

Data Sheet 5_Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems.pdf מאת Kosuke Sakaguchi (21249107)

"...Furthermore, the differentiated organoids specifically responded to a bitter compound, suggesting that pancreatic tuft cells may play a role in detecting potentially harmful chemicals. Finally, immunohistochemical analysis identified tuft cells in the non-human primate pancreas, supporting their involvement in sensing harmful compounds and regulating protective responses within the pancreas...."

Data Sheet 2_Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems.pdf מאת Kosuke Sakaguchi (21249107)

"...Furthermore, the differentiated organoids specifically responded to a bitter compound, suggesting that pancreatic tuft cells may play a role in detecting potentially harmful chemicals. Finally, immunohistochemical analysis identified tuft cells in the non-human primate pancreas, supporting their involvement in sensing harmful compounds and regulating protective responses within the pancreas...."

Table 1_Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems.docx מאת Kosuke Sakaguchi (21249107)

"...Furthermore, the differentiated organoids specifically responded to a bitter compound, suggesting that pancreatic tuft cells may play a role in detecting potentially harmful chemicals. Finally, immunohistochemical analysis identified tuft cells in the non-human primate pancreas, supporting their involvement in sensing harmful compounds and regulating protective responses within the pancreas...."

Crystal Structure of the <i>Escherichia coli</i> Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin מאת Frédéric V. Stanger (585551)

Asymmetric Catalysis with an Inert Chiral-at-Metal Iridium Complex מאת Liang-An Chen (1932571)

Asymmetric Catalysis with an Inert Chiral-at-Metal Iridium Complex מאת Liang-An Chen (1932571)

Image_9_Spatio-Temporal Pattern of Dinoflagellates Along the Tropical Eastern Pacific Coast (Ecuador).JPEG מאת Gladys Torres (5846285)

"...Climate change scenarios predict an increase in water surface temperature and extreme events frequency in tropical areas, so it is crucial to involve policy-makers and stakeholders in the implementation of future laws involving long-term monitoring and sanitary programs, not covered at present...."

Image_3_Spatio-Temporal Pattern of Dinoflagellates Along the Tropical Eastern Pacific Coast (Ecuador).jpeg מאת Gladys Torres (5846285)

"...Climate change scenarios predict an increase in water surface temperature and extreme events frequency in tropical areas, so it is crucial to involve policy-makers and stakeholders in the implementation of future laws involving long-term monitoring and sanitary programs, not covered at present...."

Image_7_Spatio-Temporal Pattern of Dinoflagellates Along the Tropical Eastern Pacific Coast (Ecuador).jpeg מאת Gladys Torres (5846285)

"...Climate change scenarios predict an increase in water surface temperature and extreme events frequency in tropical areas, so it is crucial to involve policy-makers and stakeholders in the implementation of future laws involving long-term monitoring and sanitary programs, not covered at present...."

Image_1_Spatio-Temporal Pattern of Dinoflagellates Along the Tropical Eastern Pacific Coast (Ecuador).JPEG מאת Gladys Torres (5846285)

"...Climate change scenarios predict an increase in water surface temperature and extreme events frequency in tropical areas, so it is crucial to involve policy-makers and stakeholders in the implementation of future laws involving long-term monitoring and sanitary programs, not covered at present...."

Image_6_Spatio-Temporal Pattern of Dinoflagellates Along the Tropical Eastern Pacific Coast (Ecuador).jpeg מאת Gladys Torres (5846285)

"...Climate change scenarios predict an increase in water surface temperature and extreme events frequency in tropical areas, so it is crucial to involve policy-makers and stakeholders in the implementation of future laws involving long-term monitoring and sanitary programs, not covered at present...."