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Reconstructed haplotype trees showed different topologies across individuals.
منشور في 2025الموضوعات: -
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Data_Sheet_1_Computational Reconstruction of Clonal Hierarchies From Bulk Sequencing Data of Acute Myeloid Leukemia Samples.PDF
منشور في 2021"…We investigate which problems occur during reconstruction of clonal hierarchies from bulk sequencing data. …"
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CLEMENT: GENOMIC DECOMPOSITION AND RECONSTRUCTION OF NON-TUMOR SUBCLONES
منشور في 2023"…In this study, we developed a new algorithm CLEMENT, which conducts accurate decomposition and reconstruction of multiple subclones in genome sequencing of non-tumor (normal) samples. …"
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Inferred phylogenies for POP66.
منشور في 2024"…<div><p>Motivation</p><p>DNA sequencing of multiple bulk samples from a tumor provides the opportunity to investigate tumor heterogeneity and reconstruct a phylogeny of a patient’s cancer. …"