Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf by Lucyna Widacha (20981330)

“…</p>Results<p>Heart failure mice exhibited decreased exercise performance capacity as reflected by a lower total distance covered and time of running in wheels. …”

Data Sheet 1_Cardiovascular outcomes in adult patients with atrial septal defect: a nationwide population-based study.docx by Jue Seong Lee (14992676)

“…ASD closure, whether by surgery or using a device, is associated with a decreased incidence of cardiovascular outcomes in adults. …”

Data Sheet 1_Yeast cell wall derivatives as a potential strategy for modulating oral microbiota and dental plaque biofilm.docx by Torsten P. M. Scheithauer (10950975)

“…</p>Conclusion<p>This study has demonstrated the potential of yeast cell wall derivatives to positively impact oral health by significantly reducing biofilm density, modulating the oral microbial composition, and decreasing the production of short-chain fatty acids. …”

Supplementary Material for: Phosphorus restriction prevents rapamycin-induced kidney damage in rats by Raya A.I. (19823163)

Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx by Dehua Luo (22275916)

“…</p>Results<p>Resveratrol markedly attenuated collagen deposition and reduced hydroxyproline levels, a central marker of fibrotic progression. It significantly inhibited the accumulation of extracellular matrix components and modulated profibrotic mediators. …”

Data Sheet 1_Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis.docx by Aierpati Moheteer (21522284)

“…Therapeutic evaluation in a DSP nanoparticles-treated mouse liver hydatid model revealed that the DSP nanoparticles-H group significantly reduced liver, spleen, and vesicle weights compared to both control and albendazole (ABZ)-treated groups (P <0.05). …”

Dataset for Generative artificial intelligence models in clinical infectiousdisease consultations: a cross-sectional analysis among specialists andresident trainees by Kwan Yeung Edwin Chiu (20718422)

“…Specialists consistently rated the responses more favorably than resident trainees, highlighting a discrepancy in clinical judgment. Cost analysis revealed decreasing operating expenses over time, but model performance was not directly correlated with cost. …”

Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx by Carlos A. R. Sánchez (21288050)

Supplementary Material for: Safety profile of intravitreal Dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies. by figshare admin karger (2628495)

“…In general, the peak IOP increase was typically observed 60 days post-DEX-i injection, followed by a decrease in the subsequent months. In most patients, these IOP-related AEs were successfully and efficiently managed with topical IOP-lowering medication, although some patients required additional treatments (i.e., laser or surgery). …”

Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Data_Sheet_1_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

Data_Sheet_2_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

DataSheet1_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.docx by Xiang Li (114679)

“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”

DataSheet2_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.xlsx by Xiang Li (114679)

“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”

Relationship between purposeful rumination and post-traumatic growth of college students who experienced childhood trauma: a regulated intermediary model Checklist by Sanglin Zhao (20599835)

“…Results: Correlation analysis showed that purposive rumination, positive coping and post-traumatic growth were significantly correlated. Regression analysis showed that purposive rumination had a significant direct effect on post-traumatic growth (β=0.148, P<0.001) . …”

Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx by Youqiong Xu (18161893)

“…Adherence to a healthy lifestyle (favorable [OR = 0.69, 95%CI: 0.59–0.82] and extremely favorable [OR = 0.54, 95%CI: 0.43–0.68]) was associated with a reduced risk of multiple comorbidities, with a trend toward a decreased risk of multiple comorbidities as the number of healthy lifestyles increased (p < 0.001). …”

Table 1_Temporal trends and geographic disparities in thyroid cancer burden: a global analysis from 1990 to 2021.doc by Zuzhi Zhao (21724217)

“…</p>Conclusion<p>From 1990 to 2021, the global health burden of thyroid cancer increased significantly, with marked geographical disparities. …”

Data Sheet 1_TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury.zip by Yunsheng Zhang (474242)

“…Background<p>Traumatic brain injury (TBI) triggers a cascade of neuroinflammatory responses mediated by microglial activation, which significantly contributes to secondary brain damage. …”

Cell-targeted transgenic control of 5HT_2AR levels in neurons and glia during the experience-dependent critical period. by Vanessa Kay Miller (19775496)

“…Two-way ANOVA with Tukey’s multiple comparison shows EB experience-dependent increase in 5HT_2A receptor levels in both transgenic controls (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 5.38 × 10⁻¹⁰, <i>elav</i>-Gal4; <i>p</i> = 0.0205), a significant decrease in 5HT_2A receptor levels in both RNAi conditions (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 4.63 × 10⁻¹⁰, <i>elav-</i>Gal4; <i>p</i> = 1.05 × 10⁻⁹), and a significant elevated EB response with glial <i>5HT</i>_<i>2A</i><i>R</i> OE (<i>n</i> = 10/condition, <i>p</i> = 2.36 × 10⁻⁹). …”