Supplementary Material for: m6A eraser FTO promotes ATF3 expression impairing podocyte autophagy in diabetic nephropathy by figshare admin karger (2628495)

“…Here, we identify the m6A demethylase FTO as a critical driver of DN. FTO expression is significantly upregulated in podocytes from patients with DN and correlates with increased expression of ATF3, which acted as a transcriptional repressor inhibiting podocyte autophagic flux. …”

Image 1_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Image 2_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Data Sheet 1_Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis.docx by Aierpati Moheteer (21522284)

“…Therapeutic evaluation in a DSP nanoparticles-treated mouse liver hydatid model revealed that the DSP nanoparticles-H group significantly reduced liver, spleen, and vesicle weights compared to both control and albendazole (ABZ)-treated groups (P <0.05). …”

Dataset for Generative artificial intelligence models in clinical infectiousdisease consultations: a cross-sectional analysis among specialists andresident trainees by Kwan Yeung Edwin Chiu (20718422)

“…Specialists consistently rated the responses more favorably than resident trainees, highlighting a discrepancy in clinical judgment. Cost analysis revealed decreasing operating expenses over time, but model performance was not directly correlated with cost. …”

Data_Sheet_1_MakC and MakD are two proteins associated with a tripartite toxin of Vibrio cholerae.pdf by Nandita Bodra (19793703)

“…Through deletion mutant analysis, we found that individual deletions of makC or makD do not significantly affect MakA expression or secretion. However, the deletion of both makC and makD impairs the expression of MakB, which is directly downstream, and decreases the expression of MakE, which is separated from makCD by two genes. …”

Supplementary Material for: Glucosamine use reduces the risk of first-ever optic neuritis: A nationwide 16-year longitudinal analysis by Yang Y.-Y. (4130872)

“…Conclusion: Taiwanese glucosamine users have a decreased risk of developing ON. Our work provides a theoretical basis for expanding glucosamine indications in regions with minimal prevalence of ON.…”

Table 1_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Table 1_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx by Carlos A. R. Sánchez (21288050)

Supplementary Material for: Safety profile of intravitreal Dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies. by figshare admin karger (2628495)

“…In general, the peak IOP increase was typically observed 60 days post-DEX-i injection, followed by a decrease in the subsequent months. In most patients, these IOP-related AEs were successfully and efficiently managed with topical IOP-lowering medication, although some patients required additional treatments (i.e., laser or surgery). …”

Table 1_Angiotensin converting enzyme inhibitors and angiotensin receptor blockers impact on the gut microbiome: a systematic review.docx by Elisabeth M. Wang (22480771)

“…In the human study, ACEi/ARB use did not significantly alter microbial diversity, but decreased populations of facultative aerobic pathogens including Staphylococcus and Enterobacterales. …”

Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx by Chengna Wang (21535973)

“…</p>Methods<p>Eight databases were searched for randomized controlled trials (RCTs) comparing XYS preparations to a low-iodine diet (LID), selenium yeast (SY), levothyroxine (LT4), or Ophiocordyceps sinensis (OS) for HT treatment. …”

Supplementary file 2_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip by Chengna Wang (21535973)

“…</p>Methods<p>Eight databases were searched for randomized controlled trials (RCTs) comparing XYS preparations to a low-iodine diet (LID), selenium yeast (SY), levothyroxine (LT4), or Ophiocordyceps sinensis (OS) for HT treatment. …”

Supplementary file 1_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip by Chengna Wang (21535973)

“…</p>Methods<p>Eight databases were searched for randomized controlled trials (RCTs) comparing XYS preparations to a low-iodine diet (LID), selenium yeast (SY), levothyroxine (LT4), or Ophiocordyceps sinensis (OS) for HT treatment. …”

DataSheet1_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.docx by Xiang Li (114679)

“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”

DataSheet2_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.xlsx by Xiang Li (114679)

“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”

Relationship between purposeful rumination and post-traumatic growth of college students who experienced childhood trauma: a regulated intermediary model Checklist by Sanglin Zhao (20599835)

“…Results: Correlation analysis showed that purposive rumination, positive coping and post-traumatic growth were significantly correlated. Regression analysis showed that purposive rumination had a significant direct effect on post-traumatic growth (β=0.148, P<0.001) . …”