ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer by Ana García-García (17779885)

“…This study delves into the investigation of the role of the elongase ELOVL6 in c-MYC-induced cell transformation and its potential as a therapeutic target in PDAC. Here, we demonstrate that c-MYC regulates lipid elongation to promote cell transformation, offering a new avenue for therapeutic intervention. …”

Video 2_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…</p>Methods<p>Here we present the results of our one-arm open-label pilot clinical study of our novel biologics, a DNA plasmid encoding SQSTM/p62, in 17 companion dogs suffering from OA. …”

Video 3_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…</p>Methods<p>Here we present the results of our one-arm open-label pilot clinical study of our novel biologics, a DNA plasmid encoding SQSTM/p62, in 17 companion dogs suffering from OA. …”

Video 1_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…</p>Methods<p>Here we present the results of our one-arm open-label pilot clinical study of our novel biologics, a DNA plasmid encoding SQSTM/p62, in 17 companion dogs suffering from OA. …”

Table 1_Phytotoxic effects of cigarette smoke on indoor plant Epipremnum aureum: in vivo analysis using chlorophyll a fluorescence transients.docx by Garishma Shah (21758924)

“…Chlorophyll a fluorescence (ChlF) analysis revealed impaired PSII photochemistry, as evidenced by reduced fluorescence yields and a significant decrease in fluorescence intensity at higher smoke exposures. …”

Minimal data set. by Daan P. van den Brink (9900073)

“…Plasma has been suggested as an alternative resuscitation fluid but it is unclear whether previously observed benefits were due to the type of fluid, or due to less volume required to restore tissue perfusion. We hypothesized that resuscitation with plasma reduces endothelial injury, inflammation, and organ injury compared to similar and higher volumes of crystalloids in a rat pneumosepsis model.…”

Modulation of renal inflammation and tubular injury by calcitriol in patients with early diabetic kidney disease: a randomized controlled trial by Pringgodigdo Nugroho (15460802)

“…Although UACR decreased more in the calcitriol group, the difference was not statistically significant (<i>p</i> = 0.099). …”

MaMsb2, a signaling mucin, is involved in conidiation, stress tolerances, and virulence in the entomopathogenic fungus <i>Metarhizium acridum</i> by Hongfen Dai (21975247)

“…The absence of <i>MaMsb2</i> led to a delay in conidial germination and an increase in conidial yield due to a shift in the conidiation pattern. …”

Data Sheet 1_Host identity, more than elevation, shapes bee microbiomes along a tropical elevation gradient.pdf by Andrea Pinos (22268176)

“…Our findings indicate a general decrease in bacterial diversity and a high turnover of microbial taxa along the elevation gradient, with notable differences among host tribes. …”

Comparison of demographic features. by Yueju Cai (20978633)

“…Additionally, a decrease in birth weight was significantly linked to an increased risk of readmission (OR = 0.998, P = 0.013), although the effect size was relatively small.…”

Data. by Yueju Cai (20978633)

“…Additionally, a decrease in birth weight was significantly linked to an increased risk of readmission (OR = 0.998, P = 0.013), although the effect size was relatively small.…”

Comparison of examination test and treatment. by Yueju Cai (20978633)

“…Additionally, a decrease in birth weight was significantly linked to an increased risk of readmission (OR = 0.998, P = 0.013), although the effect size was relatively small.…”

Data Sheet 1_Comparative efficacy and safety of antidiabetic agents for post-transplant diabetes mellitus: a network meta-analysis.docx by Shanbiao Hu (15063765)

“…Compared to placebo, insulin produced the greatest reductions in HbA1c (mean difference [MD] − 0.35, 95% CI − 0.90 to 0.20) and FPG (MD − 9.06 mmol/L, 95% CI − 18.66 to 0.53). …”

Table 1_Spatial stratified heterogeneity of mumps incidence in China: a Geodetector-based analysis of driving factors.xlsx by Ke Hu (84619)

“…</p>Results<p>The findings revealed a distinct west-to-east decreasing trend of mumps incidence in China, demonstrating significant spatial autocorrelation primarily manifested as high-high clustering in western areas and low-low clustering in eastern regions. …”

Conditions of the shear creep tests. by Chuang Wang (319638)

“…The Burgers model can simulate the rheological process of the residual soil samples with different RCs. The RC has a significant effect on the shear strength and the long-term strength of the residual soil. …”

Long-term strength of the residual soil samples. by Chuang Wang (319638)

“…The Burgers model can simulate the rheological process of the residual soil samples with different RCs. The RC has a significant effect on the shear strength and the long-term strength of the residual soil. …”

Components of the Burgers model. by Chuang Wang (319638)

“…The Burgers model can simulate the rheological process of the residual soil samples with different RCs. The RC has a significant effect on the shear strength and the long-term strength of the residual soil. …”

Large direct shear apparatus. by Chuang Wang (319638)

“…The Burgers model can simulate the rheological process of the residual soil samples with different RCs. The RC has a significant effect on the shear strength and the long-term strength of the residual soil. …”

Signs of slow-sliding slope deformation. by Chuang Wang (319638)

“…The Burgers model can simulate the rheological process of the residual soil samples with different RCs. The RC has a significant effect on the shear strength and the long-term strength of the residual soil. …”

Software testing process flowchart. by Mohammadreza Namdar (22439057)

“…Results demonstrate that the developed appraoch is highly accurate and significantly faster than manual classification, which can dramatically decrease software development time and cost.…”