Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"

Description of the studied population (N = 710). حسب Maryo Baakliny (20910279)

"…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …"

Preventive measures during COVID-19 pandemic. حسب Maryo Baakliny (20910279)

"…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …"

Table 1_ADAM8 in macrophages exacerbates sepsis-induced cardiomyopathy by impeding efferocytosis.docx حسب Zhenjun Ji (11050644)

"…Introduction<p>Sepsis-induced cardiomyopathy (SICM) is a life-threatening complication characterized by acute cardiac dysfunction during sepsis., and macrophages play a crucial role in SICM pathogenesis. …"

Image 1_13C-CO2 pulse labelling evaluation of water deficit on leaf carbon dynamics and whole plant allocation in fruiting coffee.png حسب Janice Nakamya (21898532)

"…These were analysed to assess ¹³C enrichment in relation to carbon assimilation and leaf carbon changes over time. Water deficit significantly decreased carbon assimilation by 20-52% compared to well-watered plants, especially in young leaves (p< 0.05). …"

Table 1_Microwave ablation triggers OX40L-mediated disruption of TNFRSF4+ Treg immunosuppressive activity.docx حسب Runqi Guo (22481293)

"…In vivo, MWA reshaped the tumor microenvironment by significantly increasing the intratumoral CD8+/Treg ratio (P<0.001), indicating a shift toward an anti-tumor inflammatory state. …"

Data Sheet 3_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf حسب Bingbu Li (21097373)

"…Introduction<p>Deltamethrin is a pyrethroid insecticide commonly used to kill animal parasites in aquaculture. …"

Image 2_13C-CO2 pulse labelling evaluation of water deficit on leaf carbon dynamics and whole plant allocation in fruiting coffee.png حسب Janice Nakamya (21898532)

"…These were analysed to assess ¹³C enrichment in relation to carbon assimilation and leaf carbon changes over time. Water deficit significantly decreased carbon assimilation by 20-52% compared to well-watered plants, especially in young leaves (p< 0.05). …"

Supplementary file 6_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"

Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"

<b>Astragalus polysaccharide and </b><b><i>Clostridium butyricum</i></b><b> synergistically inhibit bone loss in mice with humanized intestinal flora</b> حسب Hongtao Zhang (20774453)

"…</p><p dir="ltr">In this study, we explored the effects of Astragali polysaccharide and <i>Clostridium butyricum </i>mixed feeding (APS-CB) on bone loss in mice under simulated weightlessness conditions based on the concept of synergistic effect. We used a humanized intestinal flora mouse model and showed that APS-CB significantly inhibited bone loss caused by simulated weightlessness. …"

Data Sheet 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf حسب Bingbu Li (21097373)

"…Introduction<p>Deltamethrin is a pyrethroid insecticide commonly used to kill animal parasites in aquaculture. …"

Data Sheet 1_SNP rs10748643 determines CD39 expression in T and NK cells through altering NFIC binding affinity rather than interfering with RNA splicing.docx حسب Chenxin Gan (22750214)

"…Using Cleavage Under Targets and Tagmentation (CUT&Tag) technology, we found that the binding affinity of NFIC decreases when SNP mutates from A to G, causing the reduced inhibition of NFIC on CD39 expression in T cells. …"

Presentation 1_CRIF1 gene therapy ameliorates inflammatory bowel disease by suppressing TH17 cells and fibrosis through mitochondrial function regulation.zip حسب Jin-Sil Park (294905)

"…Background<p>CR6-interacting factor 1 (CRIF1) is a nuclear transcriptional regulator and a mitochondrial inner membrane protein. …"

Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"

Table 1_Optimization of drying parameters and texture properties of winter jujube slices by radio frequency combined with hot air.xlsx حسب Yang Li (7082)

"…Vitamin C (VC) content, red and green value (a*), and drying rate (DR) were used as quality indexes, and the changing trend of texture properties was analyzed. …"

Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

"…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"

Supplementary file 1_Application of multidimensional gait feature fusion algorithm in gait assessment for patients with knee osteoarthritis.docx حسب Yuzhe Tan (22274731)

"…</p>Results<p>Multidimensional feature analysis revealed a characteristic pathological compensation pattern of “decreased cyclogram features with increased sample entropy” in the KOA group, while the TKA group demonstrated postoperative improvements in both dimensions. …"

Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx حسب Chunyu Yao (13559263)

"…</p>Results and discussion<p>We established three dosage groups (2.5 × 10⁸, 5 × 10⁸, and 1.5 × 10⁹ CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …"

Image_1_Untargeted metabolomics reveals the alteration of metabolites during the stewing process of Lueyang black-bone chicken meat.pdf حسب Ling Wang (56577)

"…During the heating process, the abundances of Ser, Ala, Tyr, niacinamide, galactose, guanosine 3′-monophosphate and inosine 5′-monophosphate in chicken meat significantly decreased and were partially dissolved in the soup. …"