Data Sheet 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

DataSheet2_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.docx by Marek Sierzega (3846406)

“…Background<p>Some experimental data suggest that myokines may play an important role in developing cancer-associated cachexia (CAC), but their relevance in humans remains poorly explored. In our study, we tested the hypothesis that circulating myokines are associated with the pathogenesis of CAC in a model population of gastric cancer.…”

Life Cycle Assessment to Quantify Global Warming and Human Health–Respiratory Impacts of Using Composites from Waste Wind Turbine Blades as Feedstock for Cement Clinker and Fibergl... by Caroline V. Cameron (22355207)

“…The increasing deployment of wind turbines also creates significant waste when turbine materials reach their end-of-life. …”

Supplementary file 1_Use of erythromycin and metoclopramide in hospitalized dogs: a multicenter historical cohort study.docx by Ee Fung Teo (21181196)

“…There were also significant differences in prokinetic use between institutions.…”

Data Sheet 1_Structural and functional characterization of gut microbiota in dyslipidemic patients from high-altitude Tibetan pastoral areas.pdf by Juanjuan Chen (127202)

“…</p>Results<p>Compared with HCs, dyslipidemic patients showed a significant reduction in gut microbial diversity. Specifically, the abundance of beneficial species—including Faecalibacterium prausnitzii, Bifidobacterium adolescentis, Bifidobacterium longum, Bifidobacterium bifidum, and Parabacteroides distasonis—was significantly decreased, while opportunistic pathogens such as Veillonella parvula, V. tobetsuensis, Streptococcus oralis, and Streptococcus mitis were notably enriched. …”

Table 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”

Image 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”

Data Sheet 1_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx by Yuwei Mi (18003969)

“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx by Maria Jordan (10265489)

“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”

Image 4_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”

Data Sheet 2_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.csv by Jiashuo Li (7865036)

“…Immunohistochemistry showed that HRG expression was decreased in HCC compared to normal tissues, whereas TUBA1B expression was elevated in HCC.…”

Data Sheet 2_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Methods<p>Utilizing random sampling, we conducted questionnaire surveys among primary care physicians from Guangxis primary medical institutions in June 2019 and October 2022, and analyzed the data with SPSS software.…”

<b>Single-cell landscape of piglet lung response with </b><b><i>Actinobacillus pleuropneumoniae</i></b> by Junhui Zhu (12532423)

“…<a href="" target="_blank">Furthermore, we identified </a>significantly augmented pathological fibroblast-like cells that contributed to the rapid development of pulmonary fibrosis. …”

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”

Image 2_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg by Jiashuo Li (7865036)

“…Immunohistochemistry showed that HRG expression was decreased in HCC compared to normal tissues, whereas TUBA1B expression was elevated in HCC.…”

Image4_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff by Alexandra Coello-Camba (6489533)

“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”

DataSheet1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.pdf by Alexandra Coello-Camba (6489533)

“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”

Image 3_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”

Image 2_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”

Table 2_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”