Table10_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.xls by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

Image2_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.jpg by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

Table6_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.xls by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

Table1_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

Image1_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.jpg by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

Table12_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.xls by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

Video1_The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study.m... by Juhina Das (17808068)

“…Flow-cytometric evidences suggest that NLGP treatment upregulated CD8⁺, IFNγ⁺, granzyme B⁺, CD11c⁺ cells in comparison to 4NQO treated mice with a decrease in Ki67⁺ and CD4⁺FoxP3⁺ cells in NLGP treated cohort. …”

Table4_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.xls by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

DataSheet2_The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical stu... by Juhina Das (17808068)

“…Flow-cytometric evidences suggest that NLGP treatment upregulated CD8⁺, IFNγ⁺, granzyme B⁺, CD11c⁺ cells in comparison to 4NQO treated mice with a decrease in Ki67⁺ and CD4⁺FoxP3⁺ cells in NLGP treated cohort. …”

Presentation1_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.pptx by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

DataSheet1_The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical stu... by Juhina Das (17808068)

“…Flow-cytometric evidences suggest that NLGP treatment upregulated CD8⁺, IFNγ⁺, granzyme B⁺, CD11c⁺ cells in comparison to 4NQO treated mice with a decrease in Ki67⁺ and CD4⁺FoxP3⁺ cells in NLGP treated cohort. …”

Table7_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…T-cells demonstrated upregulation of the immunogenic cell death signaling pathway and a decrease in the Th2 pathway genes. Macrophages showed upregulation of PD1/PD-L1 pathways along with downregulation of macrophage activation pathways (alternate and classical). …”

Data Sheet 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

“…We used Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 to make a stable Danio rerio model of crim1 deficiency, generating zebrafish that were homozygous for a 2 basepair deletion, c.339_340delCT p.Leu112Leufs*, in crim1.…”

Data Sheet 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.xlsx by Jiaxuan Liu (5185280)

“…</p>Results<p>SHTX treatment significantly altered the gut microbiota composition in T2DM rats, increasing the relative abundance of Bacteroidetes while decreasing that of Firmicutes, which was closely correlated with improved insulin sensitivity. …”

Data Sheet 1_Understanding the long-term interplay of SARS-CoV-2 immune and inflammatory responses with proteases in COVID-19 recovery: a longitudinal study.pdf by Natalia Ćwilichowska-Puślecka (21515129)

“…Key findings include a decreasing deregulatory effect on immune responses exerted by subsequent SARS-CoV-2 variants Alpha, Delta, and Omicron.…”

Data Sheet 1_Primary care and specialist physicians’ prescribing preferences for concurrent probiotic-antibiotic therapy: a multinational clinical practice survey across 13 countri... by Stephan R. Vavricka (8994197)

“…<p>Antibiotic-induced intestinal microbiota disruption represents a significant clinical concern, yet physician practices regarding concurrent probiotic supplementation remain poorly characterized across international healthcare systems. …”

Data Sheet 1_Tumor-associated MerTK promotes a pro-inflammatory microenvironment and enhances immune checkpoint inhibitor response in triple-negative breast cancer.docx by Bridget E. Crossman (18230326)

“…</p>Results<p>Overexpression of MerTK in TNBC syngeneic mouse models leads to a marked delay in tumor growth, coupled with significant increases in anti-tumor M1 macrophage, CD4+ T cell, active CD8+ T cell, active NK cell, and NKT cell populations. …”

Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

Data Sheet 1_Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled... by Jilei Hu (10156880)

“…Intestine microbial composition was analyzed by metagenomic sequencing.</p>Results<p>After a 1-week intervention on the plain, curcumin significantly increased red blood cells (RBC), hematocrit (HCT), and hemoglobin in treatment group as compared to placebo group (p < 0.05). …”

Image 2_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

“…[¹⁸F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”