Supplementary Material for: Identifying novel inflammatory protein biomarkers and drug targets of inflammatory bowel disease by integrating Mendelian randomization, bioinformatics,... by Wang F. (3215361)

“…Results: By integrating data from two cohorts, we demonstrated that genetically predicted CD40 (odds ratio [OR] = 0.878, 95% confidence interval [CI] = 0.838-0.919) and C-X-C motif chemokine ligand (CXCL)5 (OR = 0.884, 95%CI = 0.841-0.930) decreased IBD risk. …”

Atorvastatin neuronal morphology data_CP.xlsxData set: neuronal morphology by Carolyn Pytte (20641508)

“…However, we found that neuronal soma morphology differed significantly between statin-treated and control birds. …”

Evolutionarily conserved and functionally important amino acids in Artemis. by Ziwen Huang (17562948)

“…All flow cytometry data represented the mean ±  SD of three biological replicates. <i>P</i> values were analyzed with Student <i>t</i> test. ns, not significant.…”

Mitochondrial ROS generated by reverse electron transport in muscles is necessary for critical period heat stress to change NMJ development. by Daniel Sobrido-Cameán (5049743)

“…<b><b>(E)</b></b> Dot-plot quantification shows changes in levels of the GluRIIA receptor subunit at aCC NMJs quantified in (C). Data are shown with mean ± SEM, ANOVA, ****<i>p</i> < 0.00001, ‘ns’ indicates statistical non-significance. …”

Modulation of cardiovascular function by rooibos in adults at risk for cardiovascular disease by Maria Diana Hartnick (7007012)

“…The LA / AO ratio did not change significantly in all the intervention groups. Interventricular septum diameter (IVSd) in the placebo group decreased significantly (p=0.002) from 1.33 cm ± 0.030 cm to 1.25 cm ± 0.03 cm with no positive change in the fermented rooibos group, while the green rooibos group demonstrated a significantly (p=0.002) decreased diameter from 1.28 cm ± 0.04 cm to 1.19 cm ± 0.03 cm. …”

Table 6_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx by Nirmal Parajuli (751983)

“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”

Data Sheet 1_Association of body roundness index with cardiovascular disease in patients with cardiometabolic syndrome: a cross-sectional study based on NHANES 2009-2018.pdf by Xiaohua He (361530)

“…For CVD, stratified analyses did not show significant difference between strata. For CHF, BMI interacted with the association, with BRI being associated with decreased risk of CHF in a subgroup of normal weight subjects and increased risk of CHF in a subgroup of obese subjects. …”

Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

“…The analysis included 25,178 American adults. We examined the association between the Composite Dietary Antioxidant Index (CDAI) and the prevalence of sleep disorders. …”

Image 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.tif by Man Zhao (314232)

“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”

Table 3_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Supplementary Material for: Dorsal Column Spinal Cord Stimulation Attenuates Brain-Spine Connectivity through Locomotion and Visuospatial-Specific Area Activation in Progressive Fr... by Zemmar A. (11259339)

“…Introduction: Freezing of gait (FOG) is a clinical phenomenon with major life impairments and significant reduction in quality of life for affected patients. …”

Data Sheet 2_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.pdf by Man Zhao (314232)

“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”

Supplementary file 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”

Table_3_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.DOCX by Ling Li (38566)

“…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …”

Table 1_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.docx by Guanfei Zhao (3815596)

“…</p>Results<p>Patients with SLE exhibited significantly decreased MMP-Low in some peripheral lymphocyte subsets. …”

DataSheet3_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Data Sheet 2_Featured intestinal microbiota associated with hepatocellular carcinoma in various liver disease states.docx by Xiu Sun (8539698)

“…By combining microbiota profiles with clinical indicators, we developed a predictive nomogram that achieved an AUC of 0.865 in the training cohort and 0.848 in the external validation cohort.…”

Data Sheet 1_Individualization of clinical target volume delineation in eccentric nasopharyngeal carcinoma: a prospective comparative study.docx by Yunrui Song (10672668)

“…</p>Results<p>Our results showed that compared with conventional CTV, the volume of CTV decreased significantly (P< 0.05) through individualizing delineation for eccentric NPC, especially CTV1 volume (95.81 cm³ vs. 57.57 cm³, P < 0.001). …”

Table 1_Unveiling the gut-heart potential connection: microbiota’s role in kawasaki disease and coronary artery lesions.docx by Qing Yang (67856)

“…Thirteen genera showed statistically significant changes, including Enterococcus, Bacteroides, Faecalibacterium, Agathobacter, Lachnospiraceae_NK4A136_group, Roseburia, Monoglobus, etc. …”

Supplementary Material for: How the COVID-19 Pandemic Impacted Neurological Hospital Admissions in Germany - A Retrospective Analysis by figshare admin karger (2628495)

“…While overall admissions decreased, average case severity was significantly higher. …”