Data Sheet 1_Unveiling frailty: comprehensive and sex-specific characterization in prematurely aging PolgA mice.pdf by Dilara Yılmaz (19710658)

“…While these approaches have been applied to aging mice, their effectiveness in prematurely aging mouse models such as PolgA^D257A/D257A (PolgA) has not been completely explored. We demonstrated that frailty became evident in PolgA mice around 40 weeks, validated through body weight loss, reduced walking speed, decreased physical activity, and weaker grip strength. …”

Data and code for "Sympathetic vasomotion as an early marker of hemorrhage." by Peter Pellegrino (20875475)

“…The difference in the vasomotion profiles between the innervated and denervated kidneys increased significantly prior to increases in heart rate or decreases in blood pressure. …”

Water bridges by Raman Jangra (19231711)

“…To delineate the structural role of water molecules in shaping the interactions between RNA and proteins, we comprehensively analyzed a dataset of 329 high-resolution crystal structures of RNA–protein complexes to identify water-mediated hydrogen-bonded contacts at the RNA–protein interface. …”

Supplementary Figures_Fainshtein.pdf by Kfir Sharabi (21415808)

“…Furthermore, we show that depleting <i>Hdac1</i> in mouse primary hepatocytes and liver tissue reduces glucose production, consistent with decreased PGC-1α activity. …”

Mapping global urban inequality under climate change and its interaction with sustainable development by Yinshuai Li (20382495)

“…<p>Global cities are significantly affected by climate change, leading to increased inequality and further vulnerability among marginalized groups. …”

Table_2_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table_3_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table_1_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xlsx by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Supplementary file 1_Interspecific association characteristics of Alternanthera philoxeroides-invaded communities and their latitudinal variations.docx by Hao Wu (65943)

“…The association intensity between terrestrial accompanying species significantly decreased with increasing latitude, and the association intensity between aquatic accompanying species varied weakly along the latitudinal gradient. …”

Data Sheet 2_Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.pdf by Anita Meinke (14137836)

“…</p>Results<p>Spinal flattening was observed during micro-gravity exposure, with changes most pronounced in the upper lumbar and lower thoracic spine. Mean-normalized area between the back and backpack decreased significantly in micro-gravity compared to earth-gravity (p = 0.001), but not during hyper-gravity (p = 1.00). …”

Data Sheet 1_Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.pdf by Anita Meinke (14137836)

“…</p>Results<p>Spinal flattening was observed during micro-gravity exposure, with changes most pronounced in the upper lumbar and lower thoracic spine. Mean-normalized area between the back and backpack decreased significantly in micro-gravity compared to earth-gravity (p = 0.001), but not during hyper-gravity (p = 1.00). …”

Image 1_Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture syste... by Yunfeng Yao (7136525)

“…It was found that both PTGM and PT remarkably decreased the average bulk density (BD), while elevated the mean soil porosity (SP) in 0–30 cm soil layer. …”

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 by Arijit Ghosh (1304952)

“…Background<p>Previously we showed that elevated cerebrospinal fluid (CSF) levels of kininogen during the acute phase of encephalitis are associated with symptomatic epilepsy. …”

Supplementary file 1_Association between the difference in cystatin C and creatinine-based eGFR and risks of multiple cardiovascular diseases: a prospective cohort study.docx by Zhiyu Qiao (12514712)

“…</p>Results<p>During a mean follow-up of 13.1 years, the positive eGFR_diff group exhibited significantly lower mortality, cardiovascular disease (CVD) incidence, and the occurrence of CVD-related conditions. …”

Data Sheet 1_Susceptibility to and severity of tuberculosis infection in mice depends upon MHC-II-determined level of activation-inhibition balance in CD4 T-cells.pdf by Nadezhda Logunova (831700)

“…<p>Previously we have shown that H2-congenic recombinant mice of the B6.I-9.3 (H2-Ab1^j) strain are significantly more susceptible to tuberculosis (TB) infection compared to their C57BL/6 (B6, H2-A^b) ancestors. …”

DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx by Ping Sun (59933)

“…However, the global age-specific death rate significantly decreased from 2.96 (2.76, 3.15) to 2.86 (2.61, 3.11), and the age-specific DALY rate remained stable. …”

Table 2_Shifts in marine bird abundance and species composition following the 2014−2016 Pacific marine heatwave.docx by Sarah A. Hoepfner (21334676)

“…The overall density of winter marine birds decreased and species composition significantly changed in PWS following the PMH. …”

Raw data by Jiaxin Wang (21706805)

“…The results of this study indicate that compared to the model group, the content of regulatory enzymes and main products (mainly GCK) of the glycolytic pathway significantly decreased after administration of Rb1, and the key enzyme ACC for fatty acid synthesis also significantly decreased.…”

Image 1_Uptake of iron from ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells.tiff by Agata Tarczykowska (20620430)

“…Iron uptake (ferritin L) from ferrous fumarate (0.5 mM, 24 h) in DMT1 silenced cells was significantly decreased (60% ± 11%) in comparison to iron controls while a 1-h dose of ferrous fumarate (0.5 mM) significantly decreased ferritin L formation in the presence of the clathrin inhibitor chlorpromazine (61% ± 10%, in post-confluent cells and 37% ± 9% in non-confluent cells). …”

Table 1_Shifts in marine bird abundance and species composition following the 2014−2016 Pacific marine heatwave.docx by Sarah A. Hoepfner (21334676)

“…The overall density of winter marine birds decreased and species composition significantly changed in PWS following the PMH. …”