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greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
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16301
Table 2_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”
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16302
Table 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.xlsx
Published 2025“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”
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16303
Table 11_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”
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16304
Supplementary file 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.docx
Published 2025“…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”
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16305
Table 1_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”
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16306
Table 9_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”
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16307
Table 5_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”
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16308
Table 3_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”
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16309
Table 6_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”
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16310
Molecular features influencing clinical outcome of advanced HER2-positive gastric cancer receiving trastuzumab plus chemotherapy
Published 2025“…Additionally, after treatment, TMB significantly increased in non-responders, while CIN significantly decreased in responders.…”
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16311
Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway
Published 2025“…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …”
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16312
Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx
Published 2025“…Protein and mRNA expression analyses revealed that high-dose baicalein upregulated the expression of FTH1, GPX4, SLC7A11, SLC3A2 and Nrf2, while downregulating ACSL4 significantly. …”
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16313
SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool
Published 2025“…Almost all management strategies except current management led to overall decreases in effort and as a result, the general ecosystem impact to a level where GES was attained (habitats and foodwebs) or the impact was decreased by at least 20% (bycatch). …”
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16314
Supplementary file 1_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.docx
Published 2025“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”
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16315
Table 2_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.csv
Published 2025“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”
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16316
Plant species loss reduces rare soil microbes through diversity effect amplified by multitrophic interactions
Published 2025“…We found that the removal of rare forbs, rather than dominant species and common plants, significantly decreased the richness of soil bacteria and fungi by decreasing rare microbial taxa in later years. …”
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16317
Table 1_Exploring the role of LOX family in glioma progression and immune modulation.docx
Published 2025“…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”
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16318
Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg
Published 2025“…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”
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16319
Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff
Published 2025“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”
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16320
Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion
Published 2025“…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …”