Image_1_D-Serine Contributes to Seizure Development via ERK Signaling.tif حسب Tie Ma (6505097)

"…L-aspartic acid β-hydroxamate (LaaβH), an inhibitor of SR, significantly prolonged the latencies of seizures, shortened the durations of seizures, and decreased the total EEG power in rats. …"

Image_5_D-Serine Contributes to Seizure Development via ERK Signaling.tif حسب Tie Ma (6505097)

"…L-aspartic acid β-hydroxamate (LaaβH), an inhibitor of SR, significantly prolonged the latencies of seizures, shortened the durations of seizures, and decreased the total EEG power in rats. …"

Image_2_D-Serine Contributes to Seizure Development via ERK Signaling.tif حسب Tie Ma (6505097)

"…L-aspartic acid β-hydroxamate (LaaβH), an inhibitor of SR, significantly prolonged the latencies of seizures, shortened the durations of seizures, and decreased the total EEG power in rats. …"

The role of Cathepsin inhibitors in RGC damage in hypoxic retina. حسب Emi Nakajima (21703141)

"…Treatment with neither Odanacatib nor SID26681509 reduced the percentage of PI-positive RGCs, whereas the positive control SNJ-1945 significantly decreased the percentage. Data are means ± SD (n = 3). …"

Data Sheet 1_Negative effects of adverse childhood experiences and absence of positive childhood experiences on healthcare employees: survey findings built on 10 years of trauma-in... حسب Laneita Williamson (20506838)

"…Having 0–2 PCEs relative to 6–7 PCEs was also significantly associated with greater odds of past 2-week compassion fatigue, a lower resilience score, and decreased odds of reported organizational belonging measures. …"

Data Sheet 1_Morphological changes of lenticels and their role in gas exchange and sprouting physiology of potato tubers during postharvest storage.docx حسب Lembe S. Magwaza (18148945)

"…This study aimed to investigate morphological variations and spatial distribution of lenticels and apical buds and to identify their potential role in tuber respiration rate and sprouting of five potato cultivars (‘Hermes’, ‘Lady Claire’, ‘Lady Rosetta’, ‘Saturna’, and ‘VR808’) during storage. Results revealed a consistent spatial pattern wherein the apical section of potato tubers exhibited significantly higher bud counts compared to lateral and stolon regions. …"

DataSheet1_Enhancing resistant starch fraction in modified elephant foot yam starch: optimizing preparation conditions and exploring tribological properties.pdf حسب Sreejani Barua (13810723)

"…However, this retention decreased significantly to 1.08% after 10 min of cooking. …"

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF حسب Huan Yu (140826)

"…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …"

Mapping global urban inequality under climate change and its interaction with sustainable development حسب Yinshuai Li (20382495)

"…<p>Global cities are significantly affected by climate change, leading to increased inequality and further vulnerability among marginalized groups. …"

Supplementary Material for: Alpinia galanga essential oil mitigates gentamycin-induced renal injury: in silico and in vivo studies حسب figshare admin karger (2628495)

"…Results: Network Pharmacology suggested Toll-like receptors 4 (TLR4), and Interleukin-1beta (IL-1β) as potential targets of Gal EO components in Genta induced renal toxicity. Gal EO significantly decreased Cr, uric acid, BUN, CysC, NGAL and Kim-1 and the urine albumin/creatinine ratio. …"

Table 1_Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits.docx حسب Changchuan Ye (11270642)

"…</p>Results and discussion<p>Our results showed that dietary supplementation with probiotic significantly promoted growth performance (e.g., increased average daily gain and decreased feed-to-gain ratio), enhanced immune function (reflected by elevated plasmic immunoglobulin levels and reduced pro-inflammatory cytokine concentrations) and improved antioxidant capacity (manifested by higher activities of superoxide dismutase and glutathione peroxidase and lower malondialdehyde content) in weaned rabbits. …"

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF حسب Huan Yu (140826)

"…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …"

<b>Inhibition of NLRP3 Inflammasome Activation by Xylitol Attenuates </b><b><i>Fusobacterium nucleatum</i></b><b>-Driven Preterm Birth</b> حسب Eui-jeong Noh (21699797)

"…Xylitol also exhibited antimicrobial effects against <i>F. nucleatum</i> within the uterine and placental tissues, correlating with decreased inflammasome activity. Notably, IL-1β levels in the placental labyrinth zone were significantly reduced in xylitol-treated, <i>F. nucleatum</i>-infected mice.…"

Data_Sheet_1_Responses of diazotrophic network structure and community diversity to alfalfa-maize intercropping are soil property-dependent.docx حسب Jinglei Zhang (311803)

"…However, in the average soil, it was the A/M system that had an altered diazotrophic structure, with an increased abundance of 11 bacterial genera and a decreased abundance of three bacterial genera (p < 0.05).…"

Data Sheet 1_Endothelial Zmiz1 modulates developmental angiogenesis in the retina.pdf حسب Nehal R. Patel (18522672)

"…<p>Angiogenesis is a highly coordinated process involving the control of various endothelial cell behaviors. …"

Data Sheet 1_Impaired SREBP1-mediated regulation of lipid metabolism promotes inflammation in chronic endometritis.pdf حسب Shigeru Matsuda (17748717)

"…A deficiency in SREBP1, a key regulator of lipid metabolism, prolonged endometrial inflammation with CD138⁺ plasma cell accumulation and induced miscarriage in LPS-induced endometritis, thereby mimicking CE. …"

Data Sheet 1_Recognition and localization of ratoon rice rolled stubble rows based on monocular vision and model fusion.docx حسب Yuanrui Li (4156645)

"…Introduction<p>Ratoon rice, as a high-efficiency rice cultivation mode, is widely applied around the world. …"

Data Sheet 1_Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.docx حسب Michael Hesse (439701)

"…The proportion of proliferating cardiac cells and ECs was significantly increased after 14 days of treatment. Mechanistically, we identified activation of the PGC-1α/ERRα signaling pathway and upregulation of its downstream target VEGF-A. …"

Image 2_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff حسب Martin Saal (21267734)

"…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …"

DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx حسب Abdul Mateen (12055673)

"…Pharmacokinetic parameters such as AUC_0-t, C_max MRT, Vd, and half-life (t_1/2) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar^®). …"