Showing 17,701 - 17,720 results of 18,392 for search 'significant ((((((mean decrease) OR (we decrease))) OR (nn decrease))) OR (a decrease))', query time: 0.57s Refine Results
  1. 17701

    Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx by Feilong Yang (1472296)

    Published 2025
    “…Western blotting demonstrated that HDGF knockdown suppressed AKT/mTOR signaling, as indicated by reduced p-AKT and p-mTOR levels, and decreased VEGFA expression.</p>Conclusion<p>Our findings establish HDGF as a key promoter of HSCC progression through dual regulation of EMT and AKT/mTOR/VEGF pathways, suggesting its potential as a therapeutic target. …”
  2. 17702

    Data Sheet 1_The pan-cancer landscape of aldo-keto reductase1B10 reveals that its expression is diminished in gastric cancer.docx by Anqi Wu (3413069)

    Published 2024
    “…In the stomach, along with the diminishing of AKR1B10 expression, CD68+ macrophage increased and CD19+ B cell decreased in gastric cancer.</p>Discussion<p>These data indicates that AKR1B10 may be an important factor in the development and progression and a potential therapeutic target for multiple cancers, but plays as a protector in the gastric tissues.…”
  3. 17703

    Image 3_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

    Published 2025
    “…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
  4. 17704

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  5. 17705

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  6. 17706

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  7. 17707

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  8. 17708

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  9. 17709

    Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x... by Yuanling Yang (22524785)

    Published 2025
    “…In contrast, 400 μM MT treatment effectively mitigated oxidative damage by coordinated activation of superoxide dismutase (SOD,+14.3%), peroxidase (POD,+21.7%), and catalase (CAT,+11.7%) activities, thereby stabilizing membrane integrity. Furthermore, MT significantly alleviated photoinhibition: F<sub>V</sub>/F<sub>M</sub> increased by 39%, Y<sub>II</sub> and qP rose, and NPQ decreased compared to salt-stressed plants, reflecting enhanced protection of the PSII reaction center and optimized light energy allocation. …”
  10. 17710

    Data Sheet 1_Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage po... by Maolin Chu (11611507)

    Published 2025
    “…More importantly, silencing renal LXN reduced RTEC senescence and M1-like phenotype macrophage polarization and consequently decreased intrarenal CaOx crystal deposition in a rat kidney stone model.…”
  11. 17711

    ABR wave I and IV parameters in response to clicks. by Carolin Jüchter (17384611)

    Published 2025
    “…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …”
  12. 17712

    Figures of manuscript "Fluvoxamine exerts anti-influenza(H1N1) effects through inhibiting apoptosis pathway" by Zhenqiao Wei (22372648)

    Published 2025
    “…This study evaluated the anti-influenza effects of fluvoxamine using H1N1-infected BALB/c mice and found that compared to the H1N1 infection group, the survival rate of mice in the fluvoxamine intervention group increased by 30% (50% <i>vs</i> 20%), with a decreased trend in body weight loss and improved lung tissue lesions. …”
  13. 17713

    Data Sheet 1_Effects of stand structure and soil depth on soil properties in Cryptomeria japonica plantations.xlsx by Laicong Luo (12521938)

    Published 2025
    “…Moreover, soils in stands with good structure exhibited higher organic carbon and total nitrogen contents, particularly in the surface soil layer (0–10 cm), while the C:N, C:P, and N:P ratios gradually decreased with increasing soil depth. The study demonstrated that maintaining a good stand structure—characterized by low canopy closure, high understory vegetation cover, and moderate stand density—can significantly improve soil porosity, water-holding capacity, and nutrient cycling efficiency. …”
  14. 17714

    Data Sheet 1_Silicon (Si) foliar treatment modulates Capsicum annuum L. (green chilli) growth and stress responses under cadmium and lead stress.docx by Waquar Akhtar Ansari (7056191)

    Published 2025
    “…For instance, at 100 mg kg<sup>−1</sup>, Cd and Pb significantly reduced the seed germination (62.5% and 50%), vigor indices (67.2% and 56.8%), root biomass (88% and 66%), chlorophyll a (75.5% and 55.5%) and carotenoids (56.4% and 48.7%) in chilly plants. …”
  15. 17715

    H2AK119ub is bidirectionally dynamic within cis-regulatory elements during neurodevelopment. by Aditya Parmar (22331873)

    Published 2025
    “…<b>(B)</b> Volcano plot depicting H2AK119ub abundance, as detected in normalized CUT&RUN data from early and late cerebellum, within SEACR-defined consensus peak regions. The significance threshold was a false-discovery rate <0.05, as defined by DiffBind [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref065" target="_blank">65</a>] (n = 4). …”
  16. 17716

    Table_4_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.DOCX by Jun Wang (5906)

    Published 2024
    “…Optimal postoperative visual outcomes may be better achieved with a CCI design featuring an increased distance from the corneal centroid and a decreased Angle-W.…”
  17. 17717

    Table_5_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.DOCX by Jun Wang (5906)

    Published 2024
    “…Optimal postoperative visual outcomes may be better achieved with a CCI design featuring an increased distance from the corneal centroid and a decreased Angle-W.…”
  18. 17718

    Image_2_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.JPEG by Jun Wang (5906)

    Published 2024
    “…Optimal postoperative visual outcomes may be better achieved with a CCI design featuring an increased distance from the corneal centroid and a decreased Angle-W.…”
  19. 17719

    Table_3_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.DOCX by Jun Wang (5906)

    Published 2024
    “…Optimal postoperative visual outcomes may be better achieved with a CCI design featuring an increased distance from the corneal centroid and a decreased Angle-W.…”
  20. 17720

    Image_1_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.JPEG by Jun Wang (5906)

    Published 2024
    “…Optimal postoperative visual outcomes may be better achieved with a CCI design featuring an increased distance from the corneal centroid and a decreased Angle-W.…”