Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

“…A subseries of these molecules displays cellular inhibition of Ras–Raf binding, as well as decreased phosphorylation of the downstream protein ERK, demonstrating that potent multivariant Ras inhibitors can be accessed from this novel pocket.…”

A) RT-qPCR analysis of <i>Yap</i>, <i>Taz</i>, and <i>Tead2</i> shows a significant decrease in transcript levels over postnatal stages from P0 to P28. by Heather L. Dingwall (14573796)

Estimated marginal mean (± SE) age group differences in the relative frequency of ball touches per minute, performed by professional soccer players on a match day for each position... by Emily Escreet (20552634)

Subjects: “…tailed statistical significance…”

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

(a) M-K test of annual average water level in Caspian Sea (unformatted fit (UF) and underidentification bias (UB) is positive and reverse order in the time series respectively; ɑ i... by Zihao Duan (17403792)

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

Estimated marginal mean values representative of the average time on ball and the relative frequency of ball touches and releases per minute of match duration, performed by profess... by Emily Escreet (20552634)

Subjects: “…tailed statistical significance…”

Assessing Bivalves as Biomonitors of Per- and Polyfluoroalkyl Substances in Coastal Environments by Shannon E. Jones (17558652)

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Charts revealing A) the significant decrease (<i>p</i> < 0.05) in the membrane integrity and B) the significant increase (<i>p</i> < 0.05) in the membrane permeability after treatment with harmalacidine hydrochloride in a representative <i>S. aureus</i> isolate (n = 3 as technical repeats of the same isolate). by Manal A. Alossaimi (10269852)

“…<p>Charts revealing A) the significant decrease (<i>p</i> < 0.05) in the membrane integrity and B) the significant increase (<i>p</i> < 0.05) in the membrane permeability after treatment with harmalacidine hydrochloride in a representative <i>S. aureus</i> isolate (n = 3 as technical repeats of the same isolate).…”

Proportion of counties that experience, on average, a decrease in salinity levels during El Niño years, divided by geographical areas. by Nicola Limodio (15138316)

General linear mixed model coefficients and significance for species-specific ungulate intensity of use as a function of cattle grazing period. by Kathryn Knodel (20036529)

Does a correlation exist between delayed vaccination and a decreased vaccine confidence? by Virginia Reverte (9046494)

“…Online questionnaire was sent to their parents, followed by a telephone questionnaire for non-responders. Regarding MMR first dose, a significant association was found between delay and birth order and intellectual/motor delay of children. …”

Effect of the VEGF-A–bevacizumab complex removal using immunoprecipitation on the concentrations of VEGF-A121, VEGF-A165, and VEGF-A. by Masashi Okawa (8951294)

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Scaling of overall health burden with yearly expenditure growth. by Margherita Molaro (17803989)

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Impact on different areas of health. by Margherita Molaro (17803989)

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Evolution of health burden and life expectancy under different expenditure scenarios. by Margherita Molaro (17803989)

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Box-whisker plots of the relative abundances (%) of coccolithophore species characteristic for the “pseudo-stadial” (PS; 1854.6–1852.8 cm), the interstadial before the YTT eruption... by Jose Dominick Guballa (19739909)

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Ni causes a decrease in membrane sterols in A549 lung epithelial cells. by Amber R. Matha (19681603)

ActAs and CoT prompt strategies do not result in decreased error rate for tasks with increasing complexity. by Jacqueline A. Jansen (14894276)

Self-correction prompt strategy results in decreased error rate for all tasks with increasing complexity. by Jacqueline A. Jansen (14894276)