Image 2_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff by Priscila Silva (556743)

“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”

P23 <i>Rik</i>^<i>null</i> vs. WT DEGs. by Erdyni N. Tsitsikov (20384719)

“…<div><p>Here, we describe a spontaneous mouse mutant with a deletion in a predicted gene <i>2310061I04Rik</i> (<i>Rik</i>) of unknown function located on chromosome 17. …”

Image 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Systemic iron overload, which leads to serious complications and affects both patients’ quality of life and overall survival, is a common clinical challenge in patients with acute myeloid leukemia (AML). We previously elucidated the direct effects of iron overload on AML cells. …”

Image 2_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

Table 1_Oral bacterial community dynamics during induction of gingival inflammation.xlsx by Bart J. F. Keijser (16884185)

“…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …”

Table 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.xlsx by Feifei Yang (334047)

“…Systemic iron overload, which leads to serious complications and affects both patients’ quality of life and overall survival, is a common clinical challenge in patients with acute myeloid leukemia (AML). We previously elucidated the direct effects of iron overload on AML cells. …”

Image 3_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif by Rong Su (2210740)

“…However, the risk associated with RNA methylation-related miRNAs (RMRMs) in the HCC immune microenvironment remains largely unknown. Here, we predicted the correlation between RMRM risk and immune cell infiltration in HCC using machine learning. …”

Image 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Systemic iron overload, which leads to serious complications and affects both patients’ quality of life and overall survival, is a common clinical challenge in patients with acute myeloid leukemia (AML). We previously elucidated the direct effects of iron overload on AML cells. …”

DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”

Image 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif by Rong Su (2210740)

“…However, the risk associated with RNA methylation-related miRNAs (RMRMs) in the HCC immune microenvironment remains largely unknown. Here, we predicted the correlation between RMRM risk and immune cell infiltration in HCC using machine learning. …”

Image 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

Image 1_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tif by Priscila Silva (556743)

“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”

Image 5_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Systemic iron overload, which leads to serious complications and affects both patients’ quality of life and overall survival, is a common clinical challenge in patients with acute myeloid leukemia (AML). We previously elucidated the direct effects of iron overload on AML cells. …”

Table 1_Ayahuasca partially preserves striatal integrity in juvenile non-human primates exposed to chronic stress: evidence from stereological evaluation.docx by Wigínio Gabriel de Lira-Bandeira (20749421)

“…Depression, a complex psychiatric disorder, affects millions of people around the world and leads to an increased risk of suicide, decreased quality of life, and functional impairment. …”

Table 4_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xls by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Table 1_The development of the neurosurgery workforce in Austria over the past quarter century: is more always better?.xlsx by Mario Mischkulnig (11659318)

“…Growth in neurosurgeon density significantly outpaced both population growth (+ 14.3%) and the overall increase of specialist physicians (+ 77.4%, p = 0.001). …”

Table 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Data Sheet 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

P14 <i>Rik</i>^<i>null</i> vs. WT DEGs. by Erdyni N. Tsitsikov (20384719)

“…<div><p>Here, we describe a spontaneous mouse mutant with a deletion in a predicted gene <i>2310061I04Rik</i> (<i>Rik</i>) of unknown function located on chromosome 17. …”

Table 6_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”