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6901
Effect of fasudil on clinical outcomes of pulmonary hypertension: a systematic review and meta-analysis
Published 2024“…</p> <p>We conducted a systematic search in several databases. …”
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6902
Image1_The fruit fly Drosophila melanogaster as a screening model for antiseizure medications.JPEG
Published 2024“…Here, we explore the efficacy of a broad spectrum of ASMs in suppressing seizure activity in two established Drosophila melanogaster bang-sensitive mutants. …”
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6903
Supplementary Material for: Global, regional, and national burden of brain and central nervous system cancers for males from 1990 to 2021 and its predicted level in the next 25 yea...
Published 2024“…Background: A study of the global burden of cerebral and central nervous system (CNS) cancers from the Global Burden of Diseases (GBD) indicates that these cancers significantly contribute to morbidity and mortality internationally. …”
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6904
Hemodynamic mechanisms underlying orthostatic hypotension in stroke survivors: a cross-sectional study
Published 2025“…</p> <p>This study aimed to determine whether orthostatic hypotension is more strongly associated with a marked cardiac output decrease or an impaired total peripheral resistance increase among individuals with stroke.…”
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6905
Image 5_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif
Published 2025“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”
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6906
Image 2_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif
Published 2025“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”
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6907
Table 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.docx
Published 2025“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”
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6908
Image 3_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif
Published 2025“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”
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6909
Image 4_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif
Published 2025“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”
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6910
Image 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif
Published 2025“…</p>Results<p>NA and D2T patients demonstrated marked elevations in fecal pro-inflammatory cytokines compared to RE and HC groups, including IL-6, Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), IL-1 beta (IL-1β), Interferon-gamma (INF-γ), IL-23, Tumor Necrosis Factor-Alpha (TNF-α), IL-21, IL-17A/F, and IL-22. Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”
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6911
Table 1_Is there a link between motor learning and mirror neuron system: TMS study.docx
Published 2025“…From the second to the fifth sessions (four sessions), motor learning was performed, as represented in the form of a serial reaction time (SRT) task.</p>Results<p>We observed a statistically significant decrease in reaction time during the process of learning within the SRT task and motor facilitation during action observation, thus reflecting putative mirror neuron activity. …”
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6912
Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx
Published 2025“…</p>Methods<p>We retrospectively analyzed 56 SLE patients who received a single dose of obinutuzumab (1000 mg) at Renji Hospital, Shanghai Jiao Tong University School of Medicine between October 2021 and March 2024. …”
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6913
Data Sheet 1_Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients with irritable bowel syndrome—A rand...
Published 2025“…A significantly higher concentration of all SCFAs was seen after intervention in Group III compared to control Group I.…”
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6914
Table 1_Cryospheric headwater genesis discrimination and social perception under megadrought and climate change scenarios: the Putaendo Valley case, Chile.docx
Published 2025“…However, despite the significant decrease in precipitation recorded during the megadrought, water continued to flow from the headwaters to the Putaendo River. …”
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6915
IntegraBrain: A multi-modal neural interface for the detection and suppression of focal epilepsy
Published 2025“…</p><p dir="ltr">Work presented here represents an evolution in focal cooling interface design beyond the existing solutions and a step towards a clinically viable device for patients.…”
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6916
Pan-cancer analysis reveals PRRT4 is a potential prognostic factor of AML
Published 2025“…After PRRT4 knockdown, the proliferation ability of THP1 cells was significantly enhanced, and the apoptosis ratio was significantly decreased.…”
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6917
DNA Metabarcoding Unveils a Decade of Dietary Shifts in Prey Fishes of an Estuarine Dolphin
Published 2025“…This disruption at the base of the food chain leads to a significant decline in fish stocks due to the depletion of prey resources, ultimately affecting top marine predators within the ecosystem. …”
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6918
Effect of alcohol on bone resorption and bone formation in female and male rats.
Published 2025“…The contents of Ca (<b>G</b>) and P (<b>H</b>) also decreased with alcohol intake. Two-way ANOVA of Ca: sex effect <i>p</i> = 0.086, alcohol effect <i>p</i> = 0.000, no significant sex-by-alcohol interaction (<i>p</i> = 0.205). …”
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6919
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6920
<i>Rab23</i> deletion perturbs ciliation in a context-dependent manner.
Published 2025“…A significant two-fold reduction in the number of primary cilia is observed in the cerebral cortex of actin-CKO mouse embryos. …”