Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Highly Sensitive and Selective Electrochemical Sensor via Cu-BTC/Au@Cu-BTC Modified Screen-Printed Electrode for the Detection of Chemical Agents by Xiaosen Li (6263651)

“…Chemical agents present significant threat to international peace, security, and human health due to their potential toxicity. …”

Data Sheet 1_Real world evidence of dupilumab effectiveness in a Colombian cohort of patients diagnosed with severe asthma.docx by Abraham Alí-Munive (21347201)

“…FEV1 measurements after one or two years of dupilumab treatment were significantly lower than baseline (p = 0.03). Mean change from baseline in FEV₁ was 302.1 ± 481.97 ml (n = 19), 282.00 ± 231.99 ml (n = 10), and 248.18 ± 281.21 ml (n = 11) in the 2–4-, 11–13-, and 19–25-month follow-up periods, respectively. …”

Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc... by Yuanhang Rong (19207540)

“…Risk of bias was evaluated following the Systematic Review Center for Laboratory Animal Experiments. The mean difference (MD) or standard mean difference (SMD) with 95% confidence intervals (CIs) were used to evaluate the effect of Tan ⅡA on cognitive function, neuropathology, neuroinflammation, oxidative stress, apoptosis, and neural/synaptic plasticity, with P < 0.05 considered a significant difference. …”

Discriminatory learning preferentially enhances reward associated input. by Rahul Garg (3064578)

“…(E) Fraction of glomeruli with significant changes post learning. Yellow: increased, dark grey: decreased, light grey: unchanged. …”

Table 1_Age-related lung structure changes by quantitative assessment: a cross-sectional study in a Chinese male cohort.docx by Meijuan Shi (16999551)

“…The quantitative parameters included lung volume (LV), mean lesion density (MLD), emphysema indexes (LAA-910, LAA-910%, LAA-950 and LAA-950%), number of bronchi (NB) and volume of bronchi (VB), as well as ratio of airway to the lung (ALR). …”

Soil carbon, nitrogen, and phosphorus stoichiometry in subtropical forests of Zhejiang, China by Tonggui Wu (20215883)

“…TP content increased and C:P ratio decreased monotonically with latitude, which supports the soil substrate age hypothesis. …”

Supplementary file 1_Changes of potential shorty-chain fatty acids producing bacteria in the gut of patients with spinal cord injury: a systematic review and meta-analysis.zip by Zaowei Zhong (20796020)

“…Firmicutes and Lactobacillus decreased. In the chronic phase, Firmicutes decreased in the SCI group. …”

Image 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…The MSCC model, developed using the StepCox [both]+plsRcox algorithm, demonstrated superior prognostic performance compared to existing models. …”

Table 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…The MSCC model, developed using the StepCox [both]+plsRcox algorithm, demonstrated superior prognostic performance compared to existing models. …”

Image 3_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…The MSCC model, developed using the StepCox [both]+plsRcox algorithm, demonstrated superior prognostic performance compared to existing models. …”

Reinforcement Learning for Assessing Route Instruction Usability in Complex Indoor Spaces by Reza Arabsheibani (14244716)

“…Our results show that RL agents successfully learn to navigate even with incomplete instructions, significantly outperforming random agents. Agents trained on diverse environments generalize well to novel settings, although performance decreases with higher environmental complexity and finer-grained instruction grammars when instructions are incomplete. …”

Table 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…The MSCC model, developed using the StepCox [both]+plsRcox algorithm, demonstrated superior prognostic performance compared to existing models. …”

Image 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…The MSCC model, developed using the StepCox [both]+plsRcox algorithm, demonstrated superior prognostic performance compared to existing models. …”

Expression changes of metalloproteinase (MMP)-9 and tissue inhibitor of matrix metalloproteinase (TIMP)-1 in immunofluorescence (IF) staining. by Minyan Sun (19751378)

“…After treatment with QLQX or empagliflozin, the expression of MMP-9 significantly decreased. <b>C,</b> MFI of TIMP-1. IF staining showed that TIMP-1 expression was significantly decreased in the model group. …”

Data Sheet 1_Campylobacter colonization and undernutrition in infants in rural eastern Ethiopia — a longitudinal community-based birth cohort study.docx by Dehao Chen (4966207)

“…</p>Results<p>The Campylobacter load in infant stools increased with age. The mean length-for-age Z-score (LAZ) decreased from −0.45 at 3–4 months of age to −2.06 at 13 months, while the prevalence of stunting increased from 3 to 51%. …”

Data Sheet 1_The effects of acupoint catgut embedding therapy on anthropometric parameters and endocrine function in obese women: a systematic review and meta-analysis.pdf by Shuangqiu Li (8083634)

“…Hormonal changes included decreased LH and FSH and increased E2.</p>Conclusion<p>Our meta-analysis demonstrates that ACET significantly improves anthropometric parameters and endocrine function in obese women, though it does not significantly impact lipid metabolism or insulin resistance. …”

Supplementary Material for: Abnormal Magnetic Resonance Imaging in the Medial Prefrontal Cortex Following Prenatal Alcohol Exposure and Placental Insufficiency in a Preclinical Mod... by figshare admin karger (2628495)

“…In the corpus callosum, the prenatal exposure/insult significantly decreased the AD (p<0.05; PAE+PI AD: 5.00x10-4 ± 4.60x10-5 mm2/s). …”

Supplementary Material for: Status of inpatients with pediatric epilepsy in children’s hospitals in China (2016–2021) by Wang J. (3112815)

“…The root-mean-square-error between the Inter-Provincial Visits Indexes decreased from 1.70 to 0.90, decreasing significantly (R2=0.8306). …”

Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx by Stephanie Dauth (13274397)

“…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”