Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx حسب Fei Yan (128878)

"…Only two serious adverse events were reported (one hyperkalemia and one decreased white blood cell count).</p>Conclusion<p>This real-world study supports the effectiveness and safety of serplulimab-based regimens as a first-line treatment for patients with locally advanced or metastatic esophageal cancer, regardless of their diverse characteristics.…"

Image10_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellul... حسب Huipeng Fang (12587509)

"…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …"

Table 1_Methodological approaches to survey complex ice cave environments - the case of Dobšiná (Slovakia).docx حسب Katarína Pukanská (20431835)

"…The study also detected dynamic changes, such as the widening of the ice tunnel by 20 cm in some sections, and a vertical ice wall in Ruffinyi’s Corridor showed localized volume losses up to 9 m³ (between 2018 and 2023). …"

Characteristics of children in the study. حسب Shijie Yu (511369)

"…</p><p>Conclusions:</p><p>This study found a significant association between myopia and worse HRQOL in primary and secondary school children. …"

Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png حسب Yu Liu (6938)

"…Although temozolomidee has a certain efficacy in the treatment of brain malignancies, its numerous adverse effects (AEs) suggest that its safety needs to be thoroughly evaluated.…"

Analyzing the global burden of 11 subtypes of congenital birth defects: trends, sociodemographic correlates, and outcomes from 1990 to 2021 حسب Enhui Yang (11844002)

"…</p> <p></p><p>The prevalence, mortality, and DALYs attributable to congenital birth defects (CBDs) significantly decreased globally from 1990 to 2021, though notable regional disparities persist.…"

Data Sheet 1_Clinical characteristics and outcome of very old (≥90 years) critically ill patients with need for intensive care after surgical intervention.docx حسب Jöran Lücke (14948623)

"…Background<p>Due to increasing life expectancy and decreasing morbidity, society is aging. Especially the group of very old patients (≥90 years) is currently increasing significantly. …"

DataSheet1_Regulation of hydrogen rich water on strawberry seedlings and root endophytic bacteria under salt stress.docx حسب Renyuan Wang (10921218)

"…Furthermore, under salt stress, HRW treatment increased the relative water content (RWC) by 12.35%, decreased the electrolyte leakage rate (EL) by 7.56%. …"

Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx حسب Shubin Wang (3105348)

"…</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. …"

Table 1_Alterations in sulcal depth and associated functional connectivity in schizophrenia with auditory verbal hallucinations.docx حسب Zhenru Guo (21811247)

"…</p>Results<p>Schizophrenia patients with auditory verbal hallucinations exhibited significantly increased sulcal depth in left hemispheric regions including the lingual gyrus, cingulate gyrus, pericalcarine cortex, parahippocampal gyrus, superior frontal gyrus, cuneus, and precuneus, whereas decreased sulcal depth was observed in right hemispheric regions encompassing the superior parietal gyrus, superior frontal gyrus, lingual gyrus, lateral occipital cortex, fusiform gyrus, postcentral gyrus, middle frontal gyrus, precentral gyrus, inferior temporal gyrus, precuneus, and parahippocampal gyrus compared to schizophrenia patients without auditory verbal hallucinations. …"

Table 1_The development of the neurosurgery workforce in Austria over the past quarter century: is more always better?.xlsx حسب Mario Mischkulnig (11659318)

"…Austria, with one of the highest physician and hospital bed densities in the OECD, provides an important case study to assess whether workforce expansion has translated into proportional service provision and maintained training opportunities.</p>Methods<p>We performed a retrospective, nationwide analysis of official health statistics from Statistik Austria covering 1997–2023. …"

Table 1_NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patie... حسب Xiaohui Zhang (81778)

"…During the 12-month follow-up of induction therapy, NLR and PLR showed a decreasing trend. Both baseline NLR and SII were positively correlated with baseline UTP and serum creatinine (SCr) levels (r = 0.112-0.148, p< 0.05 for all). …"

Effects of nano-curcumin on cell cycle and apoptosis in breast cancer cells. حسب Taraneh Givi (22793530)

"…(E, F) Bar graphs show the relative expression levels of <i>CCNA2</i>, <i>CCND1,</i> and <i>CDKN1A</i> in breast cancer cell lines. The expression levels of <i>CCNA2</i> and <i>CCND1</i> were significantly decreased in both MCF7-S and MCF7-TR cells following nano-curcumin treatment. …"

Effect of urea and K₂SO₄ on enzyme activity and biochemical changes of date fruit (<i>Phoenix dactilyfera</i> cv. ‘Zahedi’) during ripening حسب Narjes Fahadi Hoveyze (22376779)

"…</p> <p>The activity of PME, PG, cellulase, and invertase exhibited a significant elevation during date fruit ripening, and conversely, POX and PPO activity decreased.…"

Data Sheet 1_Linarin alleviates colonic barrier dysfunction induced by enterotoxic Escherichia coli in weaned piglets by regulating the gut microbiota and metabolic pathways.docx حسب Qianqian Zhang (587342)

"…Introduction<p>Enterotoxigenic Escherichia coli (ETEC) is a globally recognized gastrointestinal pathogen and a major cause of diarrhea in neonatal and post‐weaning animals, leading to significant economic losses in pig production. …"

The threshold effect analysis of the BRI on HGS. حسب Zhihao Wei (10909679)

"…<div><p>Background</p><p>Sarcopenic obesity is characterized by a combination of obesity and sarcopenia. Body round index (BRI) is a novel anthropometric index that can more accurately assess body and visceral fat levels than body mass index or waist circumference. …"

Data Sheet 1_Silver nitrate enhances antibacterial effect of colistin against intrinsic colistin resistant Edwardsiella piscicida.docx حسب Yangbin Shi (20904079)

"…E. piscicida infects many species of cultured fish and aquatic animals, posing a significant threat to the global aquaculture industry and ecological systems. …"

Presentation 1_Integrative analysis of DNA methylation, RNA sequencing, and genomic variants in the cancer genome atlas (TCGA) to predict endometrial cancer recurrence.pptx حسب Jin Hwa Hong (6523928)

"…These were visualized through volcano plots and heat maps, while decision trees and random forests classified and stratified the samples.</p>Results<p>A machine learning analysis combined with box plots showed that in the copy number-high (CN-H) recurrence group, PARD6G-AS1 had decreased methylation, CSMD1 had increased methylation, and TESC expression was higher than the non-recurrence group. …"

Uncovering Urinary Proteome Differences in Very Preterm Infants with and without Preterm Brain Injury حسب Magdalena Zasada (4524901)

"…Conversely, fatty acid-binding proteins (FABP1, FABP3, FABP4, FABP7) decreased over time in uninjured infants but increased in those with brain injury, suggesting a role in exacerbating damage. …"

Table_1_Fermentation and Storage Characteristics of “Fuji” Apple Juice Using Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus plantarum: Microbial Growth, Metabolis... حسب Jie Yang (121778)

"…During 72-h of fermentation, these LAB strains grew well in the apple juice with significant increases in viable cell counts (from 7.5 log CFU/mL to 8.3 log CFU/mL) and lactic acid content (from 0 to 4.2 g/L), and a reduction of pH value (from 5.5 to around 3.8). …"