Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

“…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. …”

Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

“…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. …”

<i>In vivo</i> treatment decreases bacterial burden and colonization of vital organs in a skin abscess biofilm infection model. by Robert L. Beckman I.V (22784303)

Comparative death probabilities of tumor-bearing mice across weeks of assessment. by Robert Botelho (20308297)

Changepoint analysis in comparison of MarBTN-specific eDNA and cancer in hemolymph. by Rachael M. Giersch (22331947)

<i>shk-1</i> mutants display decreased glycogen storage. by Longjun Pu (20685717)

Pan-cancer analyses of ANGPTL4 expression and its prognostic significance in the TCGA database. by Yu Zhang (12946)

Pan-cancer analyses of NFKB2 expression and its prognostic significance in the TCGA database. by Yu Zhang (12946)

ALKG1202R –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALKC1156Y –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALKL1196M –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALK^wt–ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. by Richard Junior Zapata Dongo (17912565)

Modeling the relationship between cancer level in hemolymph and MarBTN in tank eDNA. by Rachael M. Giersch (22331947)

Multiple distinct outcomes observed in soft-shell clams (<i>Mya arenaria</i>) after natural infection with MarBTN. by Rachael M. Giersch (22331947)

MarBTN-specific eDNA detection in each clam that was followed for MarBTN in hemolymph and eDNA. by Rachael M. Giersch (22331947)

IRE1 depletion decreases heterochromatin, DNA, and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

269 miRNAs of the 8 DSERGs. by Wei He (131453)

“…Compared with normal tissues, AAD tissues exhibited a significant decrease in CD8 T cells and an increase in NK cells and macrophages.…”

Comprehensive list of all SRGs. by Wei He (131453)

“…Compared with normal tissues, AAD tissues exhibited a significant decrease in CD8 T cells and an increase in NK cells and macrophages.…”