Juvenile demyelination impairs the maturation of PV interneurons in the PFC. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …”

All data points from Fig 2. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 5. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 8. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 3. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 1. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 4. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 9. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 7. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

All data points from Fig 6. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …”

Adult demyelination has no effect on PV interneuron’s firing rate or failures in autaptic responses. by Sara Hijazi (21656615)

Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …”

Standardized estimation of centrality index. by Song Chen (69646)

“…Furthermore, there was a noticeable decrease in the correlation between depressive symptoms and a reduced stability in the network structure during periods of high physical activity compared to those of low physical activity (88.9% → 66.7%, 80.5% → 72.2%). …”

Metabolite concentrations and statistics for data displayed in Fig 4. Statistical significance was determined using a Brown-Forsythe and Welch’s ANOVA. by Zachary T. Hying (21512605)

Covid Mzt. by Francisco Flores-de-Santiago (20391063)

“…Canonical analysis of principal coordinates during the lockdown year revealed two key patterns: (1) sewage and harbor areas displayed a significant decrease in CHLA levels alongside elevated TSMC2, while (2) mangrove forest exhibited markedly reduced CDOM in post-pandemic years. …”

Data for Fig 6D. by Xiaohua Zhang (350570)

“…In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”

Sensitivity analysis. by Jiuming Li (11711375)

“…According to the follow-up, 271 (56.7%) were in the exclusive breastfeeding group and the rest in the non-exclusive breastfeeding group (n = 207, 43.3%). A significant decrease in exclusive breastfeeding rate was observed in the prolonged TTP group compared to the short TTP group (OR=0.46, 95% CI: 0.27–0.74). …”

Characteristics of participants. by Jiuming Li (11711375)

“…According to the follow-up, 271 (56.7%) were in the exclusive breastfeeding group and the rest in the non-exclusive breastfeeding group (n = 207, 43.3%). A significant decrease in exclusive breastfeeding rate was observed in the prolonged TTP group compared to the short TTP group (OR=0.46, 95% CI: 0.27–0.74). …”

Data for Fig 5D. by Xiaohua Zhang (350570)

“…In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”