Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Summary of KEGG enrichment analysis. by Zeynab Hosseinpoor (19762319)

“…While the expression levels of <i>IRS2</i>, <i>FOXO1</i>, and <i>ERK2</i> (<i>MAPK1</i>) were significantly decreased, the <i>SERPINF1</i> gene exhibited high expression simultaneously. pAAV-delivered <i>MIR-96</i> had no adverse effect on the viability of human RPE cells. …”

Graphical abstract regarding program development. by Ana Beato (20489933)

“…<div><p>The stigma surrounding mental health remains a significant barrier to help-seeking and well-being in youth populations. …”

Phases of the intervention program. by Ana Beato (20489933)

“…<div><p>The stigma surrounding mental health remains a significant barrier to help-seeking and well-being in youth populations. …”

Consort diagram. by Ana Beato (20489933)

“…<div><p>The stigma surrounding mental health remains a significant barrier to help-seeking and well-being in youth populations. …”

Characteristics of the sample. by Ana Beato (20489933)

“…<div><p>The stigma surrounding mental health remains a significant barrier to help-seeking and well-being in youth populations. …”

Scatter plots of the linear regression for the relationship between the duration of the vegetative phase and the average mass of single inflorescences. by Torsten Schober (20485754)

Fig 5 - by Torsten Schober (20485754)

Fig 4 - by Torsten Schober (20485754)

Fig 6 - by Torsten Schober (20485754)

<i>SLC2A2</i> is associated with IGF1R pathways differentiation. by Yejin Kim (740789)

The involvement of GCN2 in eIF2 phosphorylation and <i>HaCAD, HaABCC2 and HaABCC3</i> expression. by Caihong Zhang (1633294)

Primer sequences for RT-qPCR. by Wenlong Shen (9313937)

“…Data from TCGA showed that NCOA4 shows greater downgrade in tumor tissues than in non-tumor tissues and the overall survival (OS) of patients with low NCOA4 expression was significantly shorter than that of patients with high NCOA4 expression.The qPCR results showed that NCOA4 was expressed at low levels in cholangiocarcinoma tissue specimens; the mRNA expression of NCOA4 decreased after knocking down NCOA4 in cells. …”

siRNA sequences and negative controls sequences. by Wenlong Shen (9313937)

“…Data from TCGA showed that NCOA4 shows greater downgrade in tumor tissues than in non-tumor tissues and the overall survival (OS) of patients with low NCOA4 expression was significantly shorter than that of patients with high NCOA4 expression.The qPCR results showed that NCOA4 was expressed at low levels in cholangiocarcinoma tissue specimens; the mRNA expression of NCOA4 decreased after knocking down NCOA4 in cells. …”

Antibodies used in the study. by Wenlong Shen (9313937)

“…Data from TCGA showed that NCOA4 shows greater downgrade in tumor tissues than in non-tumor tissues and the overall survival (OS) of patients with low NCOA4 expression was significantly shorter than that of patients with high NCOA4 expression.The qPCR results showed that NCOA4 was expressed at low levels in cholangiocarcinoma tissue specimens; the mRNA expression of NCOA4 decreased after knocking down NCOA4 in cells. …”

Histogram of the area factorψ. by Hong Zhang (25820)

“…The measured <i>I</i>_s decreases following a power-law trend as <i>β</i> and <i>D</i> increase, with weathering reducing the sensitivity of <i>I</i>_s to <i>β</i> but not significantly altering its sensitivity to <i>D</i>. …”

Raw dataset Fig. 6. by Hong Zhang (25820)

“…The measured <i>I</i>_s decreases following a power-law trend as <i>β</i> and <i>D</i> increase, with weathering reducing the sensitivity of <i>I</i>_s to <i>β</i> but not significantly altering its sensitivity to <i>D</i>. …”

Schematic for measuring <i>D</i> and <i>D</i>′ values. by Hong Zhang (25820)

“…The measured <i>I</i>_s decreases following a power-law trend as <i>β</i> and <i>D</i> increase, with weathering reducing the sensitivity of <i>I</i>_s to <i>β</i> but not significantly altering its sensitivity to <i>D</i>. …”

Design of the D-trial. by Torsten Schober (20485754)

“…In the context of standardized production, we therefore advocate high-density production systems that increase the proportion of desired inflorescence fractions from upper canopy layers.…”