Novel Small-Molecule miR-124 Inducer Acts as “a Physiological Brake” of Inflammation in Ulcerative Colitis by Targeting the PIK3R2/PI3K/Akt Axis by Tiantian Wang (1688881)

“…This study identified FHND5032, a novel small-molecule miR-124 inducer, as a potent therapeutic candidate for UC. …”

Effects of ABZ on the viability of <i>M. corti.</i> by Inés Guarnaschelli (18102211)

“…Viability was not significantly affected for at least 3 days, and then decreased to 38% and 10% for ABZ 1 µM and 10 µM, respectively, by day 10. …”

Initial transport rate of [³H]-hypoxanthine of PhZ mutants (V%). by Mariana Barraco-Vega (19996318)

“…Different letters (a, b, c, d) represent significant differences at p < 0.05 probability level, according to ANOVA and Tukey´s test.…”

Results of parameters a, b for curve fitting. by Hongming Li (296020)

“…The test results show that the soil expansion rate decreases from 43.7% to 37.1% with the increase of salt solution concentration. …”

Uptake of the intervention (N = 49). by Stanley Carries (21172287)

“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”

Baseline characteristics of sample by trial arm. by Stanley Carries (21172287)

“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”

CweL trial design. by Stanley Carries (21172287)

“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”

Participant Flow. by Stanley Carries (21172287)

“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”

Economic cost composition by arm and outcomes. by Stanley Carries (21172287)

“…There was a 1.32 unit (<i>p</i> = 0.085) decrease in depressive symptoms and a reduction in caregiver burden (β = -1.28, <i>p</i> = 0.020) in the intervention arm. …”

Minimal data set. by Xiaoxia Liu (294088)

“…In contrast, with a negative Soret coefficient, the growth rate of the spherical crystals increases as the coefficient decreases, and the solute concentration near the interface decreases. …”

Genes correlated with SARS-CoV-2 viral load over time are similarly expressed in independent datasets of SARS-CoV-2 infected lung and upper airway cells. by Vasanthi Avadhanula (259546)

Differential gene sets associated with the transcriptional host response to SARS-CoV-2 infection across serially collected samples. by Vasanthi Avadhanula (259546)

Differential expression patterns and functional gene groups associated with SARS-CoV-2 infection of nose organoids. by Vasanthi Avadhanula (259546)

“…<b>(c)</b> Similar to part b, but for genes decreased with SARS-CoV-2 infection. <b>(d)</b> Selected significantly enriched GO terms ⁴¹ within the genes over-expressed with SARS-CoV-2 infection in HNO204 (p<0.05, t-test). …”

Differential expression patterns and functional gene groups associated with SARS-CoV-2 viral load across serially collected samples. by Vasanthi Avadhanula (259546)

UpSet plot summarising key differentially expressed gene trends and Gene ontology analysis of differentially expressed genes present only in extremely high viral load group. by Vasanthi Avadhanula (259546)

S1 File - by Vasanthi Avadhanula (259546)

“…The human nose organoid-generated host transcriptional response captured many aspects of responses observed in the above patient samples, while suggesting the existence of distinct host responses to SARS-CoV-2 depending on the cellular context, involving both epithelial and cellular immune responses. Our findings provide a catalog of SARS-CoV-2 host response genes changing over time and magnitude of these host responses were significantly correlated to viral load.…”

Demographic characteristics of the matched groups with good quality RNA sequencing data. by Vasanthi Avadhanula (259546)

Event-free survival analysis of microvascular outcome. by Clemens Plattner (21567706)

Event-free survival analysis of macrovascular outcome. by Clemens Plattner (21567706)

Structure-Affinity-Pharmacokinetics Relationships of Novel ¹⁸F‑Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging by Yui Ishizaka (19922137)

“…In particular, BTF showed high and selective binding affinity for OX1R. In a biodistribution study using normal mice, [¹⁸F]­BTF exhibited brain uptake, and radioactivity in the brain was significantly decreased by preinjection of unlabeled BTF. …”