Genes in the top 10 up- and down-regulated. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

Differential analysis between OEG and CG groups. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

Overview of Sequencing Results. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

PCA plot of OEG group and CG group. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

siRNA sequences designed for this study. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

Data Sheet 1_Understanding the long-term interplay of SARS-CoV-2 immune and inflammatory responses with proteases in COVID-19 recovery: a longitudinal study.pdf by Natalia Ćwilichowska-Puślecka (21515129)

“…Key findings include a decreasing deregulatory effect on immune responses exerted by subsequent SARS-CoV-2 variants Alpha, Delta, and Omicron.…”

Statistics of reads aligned to gene structure. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

Protocols for real-time quantitative PCR. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

The Original gel map protein immunoblotting. by Chaoyun Yang (11523358)

“…The results of transcriptome sequencing demonstrated that the overexpression of the HADHB gene markedly altered the transcriptional profile of preadipocytes, with 170 genes exhibiting a significant increase in expression and 113 genes displaying a decrease. …”

Data Sheet 1_Global, regional, and national burden of hyperglycemia-associated colorectal cancer, 1990-2021: a systemic analysis for the Global Burden of Disease study.zip by Yijuan Liu (5195747)

“…Background<p>Colorectal cancer (CRC) is a leading gastrointestinal malignancy with rising incidence. …”

Table 1_The effects of pond purification system on intestinal function of channel catfish (Ictalurus punctatus): a focus on intestinal development, digestion and absorption, and ju... by Zhong-Bing Zheng (22253200)

“…The intestinal morphology of these channel catfish exhibited increased villus height and a reduced number of mucus cells. Furthermore, serum levels of diamine oxidase and D-lactic acid were significantly decreased in channel catfish raised in the PPS group, while the expression of genes related to the apical junction complex was significantly upregulated, suggesting improved intestinal structural integrity. …”

Supplementary file 2_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx by Wenjing Ji (720509)

“…Probiotics, combined with a multivitamin/mineral supplement, significantly reduced the BLLs in these children within 12 weeks of supplementation by 40%, similar to that of the control group, which received a placebo plus multivitamin/mineral supplement. …”

Supplementary file 1_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx by Wenjing Ji (720509)

“…Probiotics, combined with a multivitamin/mineral supplement, significantly reduced the BLLs in these children within 12 weeks of supplementation by 40%, similar to that of the control group, which received a placebo plus multivitamin/mineral supplement. …”

Data Sheet 1_Application of compost amended with biochar on the distribution of antibiotic resistance genes in a soil–cucumber system—from the perspective of high-dose fertilizatio... by Shuai Shi (333614)

“…Compost application to soils significantly decreased ARG abundance in cucumbers; SBTC had the most significant effect and reduced the number of host bacteria at the phylum level from four to three. …”

Data Sheet 1_Impacts of DRG point-based payment system on healthcare resource utilization and provider behavior: a pilot quasi-experimental study in China.docx by Xiao Huang (223709)

“…Background<p>Developing countries commonly face challenges regarding budget constraints and inadequate cost-accounting capabilities during the implementation of a Diagnosis-Related Group (DRG) payment system. …”

Data Sheet 1_Do you speak cat? Assessing the impact of a training video on human recognition of cat emotions and behaviours during play interactions.pdf by Julia S. L. Henning (22302784)

“…Previous vocational cat experience was associated with higher accuracy in negative interactions. Training had a small but significant positive impact on overall performance but paradoxically significantly decreased subtle negative behaviour recognition. …”

Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv by Jie Zheng (31208)

“…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. Mechanistically, Gyg1 knockdown significantly reduced glycogen content in myeloid cells, attenuated IL-6 and TNF-α production, alleviated LPS-induced neutrophil, and modestly decreased CD40 expression in monocytes and dendritic cells. …”

S1 File - by Dan Liu (108669)

“…Western Blot analysis indicated a significant reduction of G6PD expression in the retina, and immunofluorescence staining showed distribution of G6PD especially in the retinal endothelium cell decreased.…”

DataSheet1_Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study.zi... by Yanjun Liang (4394089)

“…Similarly, serum P was associated with a decrease in eGFRcrea (beta −0.01, P-value 2.0E−04; beta −0.005, P-value 2.0E−03) and an increase in BUN (beta 0.02, P-value 3.0E−03; beta 0.02, P-value 7.5E−07). …”

Table 1_Decadal trends and regional disparities in tuberculosis burden: a comprehensive analysis of global, African, and Southeast Asian data from the GBD 1990–2021.docx by Shiwei Xie (3617159)

“…</p>Conclusion<p>TB remains a significant public health issue, especially in Africa and Southeast Asia. …”