Supplementary Material for: ACOT4 and ACOT6 activate Akt-mTOR pathway and inhibit calcium oxalate-induced renal tubular cell injury by figshare admin karger (2628495)

“…However, ACOTs' effect on CaOx kidney stone formation remains to be explored. Here, we aimed to investigate the effect of ACOTs on CaOx kidney stone formation. …”

Table2_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Image 2_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... by Khalidah Ibraheem (9525220)

“…Scalp cooling remains the only available method to mitigate CIA, but its effectiveness varies amongst patients. We previously reported that the cytoprotective effects of cooling are temperature dependent. …”

Table3_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Data Sheet 1_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... by Junhong Yang (7807046)

“…</p>Materials and methods<p>We conducted a cross-sectional study on donor hemovigilance data reported to the national network from 2020 to 2022 in China. …”

Image 3_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... by Khalidah Ibraheem (9525220)

“…Scalp cooling remains the only available method to mitigate CIA, but its effectiveness varies amongst patients. We previously reported that the cytoprotective effects of cooling are temperature dependent. …”

Supplementary Material for: Diverse Obesity Trajectories in a Family including Identical Twins with a Pathogenic MC4R Variant by figshare admin karger (2628495)

“…Twin 2 had a sedentary lifestyle and epilepsy and had a peak BMI of 30.1 kg/m2; she responded well to naltrexone-bupropion and BMI decreased to 26 kg/m2. Conclusion: The manifestation of obesity, even in cases of monogenic obesity, can vary significantly due to the influence of environmental and lifestyle factors.…”

Extraction time and mustard concentration for extraction of aquatic oligochaetes by using wet funnel by Satoshi Kaneda (571209)

“…In Exp.S1.1, under continuous extraction, efficiency increased from 2 h to 5 h but was greater over 2 h than over 24 h using different soil samples in Exp. …”

Data Sheet 1_Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis.docx by Reema Priyanka Suram (22399759)

“…In manifest HD, both amplitude [RoM = 0.92, 95% CI (0.81 to 1.02); p = 0.00] and acrophase [RoM = 0.92, 95% CI (0.07 to 1.78); p = 0.03] significantly decreased. PD patients with sleep disorders had significantly higher melatonin concentrations than the non-sleep disorder group, with a significant test group difference of p = 0.00. …”

Presentation 1_Baduanjin exercise improves functional capacity and cardiovascular function in older adults with cardiovascular diseases: a systematic review and meta-analysis.pdf by Xingyu Hu (11171774)

“…What's more, it also decreased MLHFQ (MD: −7.00, 95% CI: −9.54 to −4.45, p = 0.0003, I² = 79%).…”

Method for establishing the multipath adaptive mitigation model considering deformation displacement of monitoring stations by Guo Zihuai (20442074)

“…The comparison between MAMM and the Multipath Hemispherical Model (MHM) indicates that, in the simulated displacement experiments, MHM’s effectiveness in mitigating multipath errors significantly decreases as the actual displacement distance increases, whereas MAMM consistently maintains an improvement rate in positioning precision of over 100%, markedly surpassing that of MHM. …”

Table 1_The impact of digital economy on the supply chain resilience of cross-border healthcare e-commerce.xlsx by Jianyu Liu (313522)

“…The results indicate that the digital economy significantly enhance supply chain resilience, with reduced reliance on foreign trade, increased export technology complexity, and decreased export concentration being key pathways for this improvement. …”

Image 2_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif by Xinxiao Gao (21717197)

“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”

Image 1_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif by Xinxiao Gao (21717197)

“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”

S1 File - by Qian Wang (32718)

“…Prior cancer history had little impact on DSS; however, the presence of prior solid cancer history, latency period of 10+ years, and prior administration of radiotherapy or chemotherapy significantly decreased OS. Prior cancer history had no effect on DSS, but survival compromised OS under specific circumstances.…”

Data Sheet 1_China’s readiness for transitioning to a low-carbon economy: mitigant and catalyst factors for a geopolitical conflict.zip by Yan Chen (4308)

“…This study examines the relationship between Low-Carbon Economic Development (LCED) and Geopolitical Risk (GPR) in China by focusing on the challenges and opportunities they present. We use a qualitative analysis to identify that rising GPR, exacerbated by market instability, resource allocation conflicts, and trade disputes, significantly hinders LCED progress. …”

Image 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.jpeg by Na Wang (193263)

“…It also increased mitochondrial function and ATP levels, reduced intracellular reactive oxygen species, and elevated intracellular GSH levels in both oocytes and embryos. Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”

Data Sheet 1_Disease burden of tuberculosis in China from 1990 to 2021 and its prediction to 2036.docx by Rong Sun (532754)

“…</p>Conclusion<p>TB burden in China has decreased significantly overall in the past years. …”

Table 1_Organic and inorganic fertilizers modulate the response of the soil microbiome to salinity stress.docx by Halima Malal (21570602)

“…Furthermore, NPK fertilization increased bacterial network complexity but decreased its stability. This study underscores the significance of employing vermicompost to improve the health of saline soils. …”

Table2_Impaired Mycobacterium tuberculosis-specific T-cell memory phenotypes and functional profiles among adults with type 2 diabetes mellitus in Uganda.xlsx by Phillip Ssekamatte (10217206)

“…</p>Results<p>Naïve CD4⁺ T cells were significantly decreased in the LTBI-DM compared to the LTBI-only participants [0.47 (0.34-0.69) vs 0.91 (0.59-1.05); (p<0.001)]. …”