Showing 17,881 - 17,900 results of 18,177 for search 'significant ((((((we decrease) OR (teer decrease))) OR (greater decrease))) OR (a decrease))', query time: 0.57s Refine Results
  1. 17881

    Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx by Jikai He (11888466)

    Published 2025
    “…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”
  2. 17882

    Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx by Jikai He (11888466)

    Published 2025
    “…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”
  3. 17883

    Exogenous jasmonic acid alleviates Cu-induced damages in guinea grass by enhancing photosynthesis, antioxidant enzyme activity and modifying associated metabolites by Jian Ren (175424)

    Published 2025
    “…The results indicated that Cu stress significantly reduced superoxide dismutase (−51.2%) and peroxidase (−38.0%), chlorophyll content, net photosynthetic rate (<i>Pn</i>), and led to decreases in leaf length, width, plant height, and biomass (−49.7%). …”
  4. 17884

    Therapeutic Administration Success Rates. by Alani Mohanad Khalid Ahmed (22693496)

    Published 2025
    “…Treated groups show an increasing trend, while untreated groups show a decreasing trend. Mesenchymal stem cells (MSCs); bone marrow-derived mesenchymal stem cells (BM-MSCs) and adipose-derived mesenchymal stem cells (AD-MSCs). …”
  5. 17885

    Data Sheet 1_Characterization of peripheral immune cells in kidney transplantation recipients under different immunosuppressive treatments.docx by Yunze Tai (21522872)

    Published 2025
    “…</p>Results<p>In KTRs, the expression of G-MDSCs and M-MDSCs was significantly higher than the HCs, while the expression of HLA-DR<sup>+</sup> monocytes, CD38<sup>+</sup>/CD28<sup>+</sup> activated T cells, CD4<sup>+</sup> naïve T cells, CD4<sup>+</sup> effector memory T cells, and central memory T cells were significantly lower. …”
  6. 17886

    MLN IFN- by Jessica Belmares-Ortega (21212731)

    Published 2025
    “…Each symbol represents a single mouse. One-way ANOVA with Tukey’s multiple comparison test was used to assess statistical significance, where * p < 0.05, ** p < 0.01, *** p < 0.001.…”
  7. 17887

    <i>Irresistible</i><sup><i>p173</i></sup> is an allele of the Cadherin-encoding gene <i>cdh16.</i> by Susannah S. Schloss (21238775)

    Published 2025
    “…<p><b>(A)</b> Conceptual translation of <i>cdh16</i> and the predicted consequences of the <i>irresistible</i><sup><i>p173</i></sup><i>,</i> and <i>cdh16</i><sup><i>co79</i></sup> mutations. …”
  8. 17888

    The recruitment of Paf1C to the <i>frq</i> ORF is regulated by the WCC activity. by Mengmeng Zhou (9197699)

    Published 2025
    “…<p>(A) The enrichment of PAF-1 (Left) or RTF-1 (Right) at the <i>frq</i> ORF middle region significantly decreased in <i>wc-2</i><sup><i>KO</i></sup> strain at DD14. …”
  9. 17889

    Data Sheet 1_Supplementary far-red light enhances the quality and root development of double-root-cutting grafted watermelon seedlings.docx by Cuinan Wu (650400)

    Published 2025
    “…The findings from this study present a practical method to enhance the quality of grafted watermelon seedlings.…”
  10. 17890

    Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression by Ming Qiu (762714)

    Published 2025
    “…<p>Porcine reproductive and respiratory syndrome virus (PRRSV) has a disastrous impact on the global swine industry. …”
  11. 17891

    Data Sheet 1_Chito-oligosaccharide composites enhanced the adaptability of cotton seedlings to salinized soil by modulating photosynthetic efficiency and metabolite.doc by Mengjie An (9501175)

    Published 2025
    “…The results showed that salt stress reduced the contents of K<sup>+</sup> and Ca<sup>2+</sup> and enhanced the content of Na<sup>+</sup> in cotton leaves compared to the control, which inhibited leaf photosynthesis and seedling growth. COS-PA application decreased leaf Na<sup>+</sup> content significantly in salt-stressed cotton seedlings by 69.70%, and increased the leaf Ca<sup>2+</sup> content, fresh weight of each plant part, transpiration rate, leaf chlorophyll concentration (Chl a), actual quantum yield, as well as stomatal conductance by 7.22%, 46.33%-96.36%, 96.65%, 44.53%, 27.15%, and 168.24%, respectively, compared with the no COS-PA application treatment. …”
  12. 17892

    Image 1_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i... by Jiacheng Gan (20413847)

    Published 2024
    “…These findings may provides a novel reference for the nutritional regulation to improve the production of Tibetan sheep.…”
  13. 17893

    Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke by Yike Wu (20982007)

    Published 2025
    “…Hence, the present study explored changes in the ubiquitinomic in early ischemic brain tissues between wildtype and ENOPH1 knockout mice using a comprehensive quantitative analysis. Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”
  14. 17894

    Image 3_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg by Chenchao Zou (22768010)

    Published 2025
    “…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
  15. 17895

    Figure 2 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes by Laura Kuett (20493991)

    Published 2025
    “…<b>D,</b> Tumor cell phenotypic cluster enrichment in each metastatic patient group compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.…”
  16. 17896

    Image 2_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i... by Jiacheng Gan (20413847)

    Published 2024
    “…These findings may provides a novel reference for the nutritional regulation to improve the production of Tibetan sheep.…”
  17. 17897

    Presentation 1_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.pptx by Chenchao Zou (22768010)

    Published 2025
    “…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
  18. 17898

    Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke by Yike Wu (20982007)

    Published 2025
    “…Hence, the present study explored changes in the ubiquitinomic in early ischemic brain tissues between wildtype and ENOPH1 knockout mice using a comprehensive quantitative analysis. Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”
  19. 17899

    Supplementary Material for: Quality of Life After Alloplastic vs. Autologous Breast Reconstruction: 'The Influence of Patient Characteristics on Outcomes' by Holt-Kedde I.L. (20616542)

    Published 2025
    “…Conclusion: This study confirms that even when adjusted for confounders, scores on two QoL sub-scales autologous breast reconstruction patients score significantly higher over time. Although autologous reconstruction remained superior regarding “Satisfaction with Breasts”, scores decreased in autologous reconstruction patients when they were depressed at baseline, underwent radiotherapy, had a history of breast cancer, or faced major complications.…”
  20. 17900

    Outcomes of Corticosteroids Combined with 15 Mg/Week Methotrexate as Initial Treatment for Acute Vogt-Koyanagi-Harada Disease by Yao Lu (185912)

    Published 2025
    “…All the eyes had retinal reattachment and the choroidal thickness significantly decreased. Sun-set glow fundus was identified in 18 eyes (23.1%). …”