Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

Exogenous jasmonic acid alleviates Cu-induced damages in guinea grass by enhancing photosynthesis, antioxidant enzyme activity and modifying associated metabolites حسب Jian Ren (175424)

"…The results indicated that Cu stress significantly reduced superoxide dismutase (−51.2%) and peroxidase (−38.0%), chlorophyll content, net photosynthetic rate (<i>Pn</i>), and led to decreases in leaf length, width, plant height, and biomass (−49.7%). …"

Data Sheet 1_Characterization of peripheral immune cells in kidney transplantation recipients under different immunosuppressive treatments.docx حسب Yunze Tai (21522872)

"…</p>Results<p>In KTRs, the expression of G-MDSCs and M-MDSCs was significantly higher than the HCs, while the expression of HLA-DR⁺ monocytes, CD38⁺/CD28⁺ activated T cells, CD4⁺ naïve T cells, CD4⁺ effector memory T cells, and central memory T cells were significantly lower. …"

Table 5_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 1_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 4_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 6_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 3_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 2_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

HSP47 inhibitor Col003 may attenuates neurological impairment in chronic ischemic stroke rats by inhibiting LCN2 حسب Kejian Zhou (22557101)

"…</p> <p>Fourteen days post-MCAO, Col003 treatment significantly decreased cerebral infarct volume and enhanced neurological function scores in rats. …"

<i>Irresistible</i>^<i>p173</i> is an allele of the Cadherin-encoding gene <i>cdh16.</i> حسب Susannah S. Schloss (21238775)

"…<p><b>(A)</b> Conceptual translation of <i>cdh16</i> and the predicted consequences of the <i>irresistible</i>^<i>p173</i><i>,</i> and <i>cdh16</i>^<i>co79</i> mutations. …"

Data Sheet 1_Supplementary far-red light enhances the quality and root development of double-root-cutting grafted watermelon seedlings.docx حسب Cuinan Wu (650400)

"…The findings from this study present a practical method to enhance the quality of grafted watermelon seedlings.…"

<i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor حسب Mo-Fei Li (21624535)

"…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …"

Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression حسب Ming Qiu (762714)

"…<p>Porcine reproductive and respiratory syndrome virus (PRRSV) has a disastrous impact on the global swine industry. …"

Data Sheet 1_Chito-oligosaccharide composites enhanced the adaptability of cotton seedlings to salinized soil by modulating photosynthetic efficiency and metabolite.doc حسب Mengjie An (9501175)

"…The results showed that salt stress reduced the contents of K⁺ and Ca²⁺ and enhanced the content of Na⁺ in cotton leaves compared to the control, which inhibited leaf photosynthesis and seedling growth. COS-PA application decreased leaf Na⁺ content significantly in salt-stressed cotton seedlings by 69.70%, and increased the leaf Ca²⁺ content, fresh weight of each plant part, transpiration rate, leaf chlorophyll concentration (Chl a), actual quantum yield, as well as stomatal conductance by 7.22%, 46.33%-96.36%, 96.65%, 44.53%, 27.15%, and 168.24%, respectively, compared with the no COS-PA application treatment. …"

Table 1_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.xls حسب Dang Li (16400478)

"…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"

Table_2_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.docx حسب Živa Frangež (5946392)

"…<p>Autophagy is a highly conserved cellular process in which intracellular proteins and organelles are sequestered and degraded after the fusion of double-membrane vesicles known as autophagosomes with lysosomes. …"

Image 13_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

"…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"

Image 1_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i... حسب Jiacheng Gan (20413847)

"…These findings may provides a novel reference for the nutritional regulation to improve the production of Tibetan sheep.…"