PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination. حسب Sara Hijazi (21656615)

"…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …"

Sequential viral infection modulates the intestinal bacterial microbiome. حسب Yuhao Li (1559569)

Sequential viral exposure shapes immune cell profiles in mucosal tissues. حسب Yuhao Li (1559569)

Effect of AUT00201 (1 µM) on PV properties after adult demyelination. حسب Sara Hijazi (21656615)

Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. حسب Sara Hijazi (21656615)

"…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …"

Adult demyelination has no effect on PV interneuron’s firing rate or failures in autaptic responses. حسب Sara Hijazi (21656615)

Comparison between juvenile and adult demyelination. حسب Sara Hijazi (21656615)

"…<p><b>A–I</b>. Juvenile demyelination leads to impairment in PV interneuron maturation whereas adult demyelination induces a decrease in the excitability of PV interneurons. …"

PRV UL4 also promotes AIM2-inflammasome activation. حسب Xiaohua Zhang (350570)

RNAi targeting of <i>upd3</i> expression in muscle of <i>Gpdh1; Ldh</i> double mutant partially suppresses the developmental arrest phenotype. حسب Madhulika Rai (4352803)

AUT00201 (1 µM) can rescue AP width in cuprizone mice. حسب Sara Hijazi (21656615)

"…<p><b>A</b>. Bath application of AUT00201 1 µm decreased the rheobase of PV interneurons from cuprizone mice but not control mice (<i>group x AUT00201 two-way repeated measures: n = 12,13 cells from 4 mice per group: F(1,12) = 0.1816, p = 0.6775; AUT00201 effect: F(1,12) = 7.122, *p = 0.0205. …"

Viral UL4 protein promotes pyroptosis in macrophage cells. حسب Xiaohua Zhang (350570)

Bar chart of state-wise annual temperature shift. حسب MD. Nahid Hassan Nishan (22264861)

"…Across most states, a slight decrease in age at menarche was observed, with the exception of Maharashtra, which showed an increase. …"

Demographic characteristics of the participants. حسب MD. Nahid Hassan Nishan (22264861)

"…Across most states, a slight decrease in age at menarche was observed, with the exception of Maharashtra, which showed an increase. …"

PRISMA flow chart of the screening process. حسب Mohamed R. Abdelraouf (21501468)

"…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …"

Forest plot of liver function tests. حسب Mohamed R. Abdelraouf (21501468)

"…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …"

Subgroup analysis of BUN based on pump type. حسب Mohamed R. Abdelraouf (21501468)

"…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …"

Subgroup analysis of ICU Stay based on pump type. حسب Mohamed R. Abdelraouf (21501468)

"…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …"

Subgroup analysis of eGFR based on pump type. حسب Mohamed R. Abdelraouf (21501468)

"…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …"

GRADE evidence profile. حسب Mohamed R. Abdelraouf (21501468)

"…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …"

Characteristics of included studies. حسب Mohamed R. Abdelraouf (21501468)

"…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …"