Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer by Jiaxing Li (113609)

“…Herein, we reported an effective and selective PRMT7 inhibitor, <b>A33</b>, which was obtained through structural optimization and exhibited potent anti-PCa efficacy in vitro and in vivo. …”

Variation of MLR of concrete under three curing conditions after F–T: (a) standard curing; (b) 5 °C curing; (c) −3 °C curing. by YongHe Liu (20477123)

The EAPC of ASMR (A), ASDR (B), Age-Standardized Rate of YLDs (C), and Age-Standardized Rate of YLLs (D) of high alcohol use-related Stroke in both sexes combined across 21 GBD reg... by Nannan Qian (10650782)

Effectiveness of abdominal bracing core exercises as rehabilitation therapy for reducing abdominal symptoms in patients with autosomal dominant polycystic kidney disease and signif... by Jaeyeong Yoo (17292907)

“…The purpose of this study was to assess the effectiveness of ABC rehabilitation exercises in reducing pain in ADPKD patients with significant PLD. Significant PLD was defined as a height-adjusted total liver volume (htTLV) exceeding 1,600 mL/m. …”

Table 1_Functional characterization of endocytic signals in the SynDIG/PRRT family members SynDIG1 and SynDIG4 in heterologous cells and neurons.xlsx by David J. Speca (20601326)

“…<p>The transmembrane protein Synapse Differentiation Induced Gene 4 (SynDIG4), also known as Proline-rich transmembrane protein 1 (PRRT1), is an AMPA-type glutamate receptor (AMPAR) auxiliary factor that is necessary for maintaining extra-synaptic pools of GluA1. Loss of SynDIG4, and the subsequent decrease in extra-synaptic GluA1, has been found to significantly impact synaptic plasticity in the hippocampus. …”

The distribution of <i>Giardia duodenalis</i> assemblages in domestic and wild populations of nonhuman mammalian species with a larger number of isolates. by Kareem Hatam-Nahavandi (7384790)

Data Sheet 1_Introduction of Panax notoginseng into pine forests significantly enhances the diversity, stochastic processes, and network complexity of nitrogen-fixing bacteria in t... by Xiaoyan Zhao (347268)

“…</p>Results and discussion<p>Sanqi cultivation triggered a decrease in the abundance of NFB but increased α diversity. …”

KEGG enrichment pathway chart (bubble chart) (A) mild PTOA group VS severe PTOA group (B) mild PTOA group VS normal group (C) Severe PTOA group VS normal group. by Peng-fei Han (694841)

Supplementary Material for: Association of platelet count and mean platelet volume with fish intake frequency: Implication for the cardioprotective effect of fish intake by figshare admin karger (2628495)

“…Introduction: Mean platelet volume (MPV) measures platelet activity, and high values indicate increased atherosclerotic cardiovascular disease (ASCVD) risk. …”

Viability of <i>L</i>. <i>intracellularis</i>. by Huan W. Yang (19746645)

Stability differences between condition 1 and other conditions across participants on the non-hemiparetic side (NHP) side. by Hyung Suk Yang (20442438)

Stability differences between condition 1 and other conditions across participants on the hemiparetic (HP) side. by Hyung Suk Yang (20442438)

Reduced cell viability in Dkp23- and Vaccine-infected PK-15 cells. by Huan W. Yang (19746645)

Regulation of NF-κB target genes. by Huan W. Yang (19746645)

Video 1_The clinical application value of mixed reality in robotic laparoscopic partial nephrectomy.mp4 by Xin Chang Zou (20129301)

“…Within the subgroup with a R.E.N.A.L. score of less than 7 points, the MR group only showed a significant reduction in operation time [(134.55 ± 150.190) min vs. (150.19 ± 28.638) min, P = 0.045], with no notable differences in other parameters. …”

CONSORT flow diagram. by Mehran Asadi-Aliabadi (8383110)

“…The interventions had statistically significant effects only on decreasing the prevalence of overweight and obesity. …”

Few-Shot Symbol Detection in Engineering Drawings by Laura Jamieson (19759235)

“…The results suggest that our method not only significantly improves symbol detection performance compared to other state-of-the-art methods but also decreases the necessary number of training instances.…”

CRISPR-Cas9-mediated mutation analysis of T₀ Stmc7 mutants. by Bikram Poudel (15989201)

Data Sheet 2_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.pdf by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

Data Sheet 1_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.docx by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”