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يعرض 6,601 - 6,620 نتائج من 7,113 نتيجة بحث عن 'significant ((((changes decrease) OR (largest decrease))) OR (larger decrease))', وقت الاستعلام: 0.44s تنقيح النتائج
  1. 6601

    Table 1_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.xlsx حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  2. 6602

    Table 1_Weizmannia coagulans BC99 regulates oxidative stress and serum metabolic pathways to improve allergic rhinitis: a randomized, double-blind, placebo-controlled trial.docx حسب Xuan Li (137217)

    منشور في 2025
    "…Furthermore, BC99 supplementation significantly decreased serum IgA, complement C3, EOS, and MDA levels (p < 0.05) while enhancing antioxidant capacity (increased GSH, stabilized SOD). …"
  3. 6603

    Image 4_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.tif حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  4. 6604

    Data Sheet 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  5. 6605

    Data Sheet 3_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  6. 6606

    Supplementary file 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.docx حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  7. 6607

    Data Sheet 4_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  8. 6608

    Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …"
  9. 6609

    DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer... حسب Huijing Ren (19986303)

    منشور في 2024
    "…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …"
  10. 6610

    Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …"
  11. 6611

    Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx حسب Ping-Heng Zhang (21785162)

    منشور في 2025
    "…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …"
  12. 6612

    DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

    منشور في 2024
    "…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"
  13. 6613

    Data Sheet 1_Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats.docx حسب Yewen Sun (8334138)

    منشور في 2025
    "…Gut microbiota associated with SBAs metabolism were significantly reduced, leading to decreased intestinal deoxycholic acid (DCA) and lithocholic acid (LCA). …"
  14. 6614

    PRMT5 isoforms during zebrafish developmental stages حسب Zain Zakaria (20354028)

    منشور في 2024
    "…Remarkably, despite the lack of any significant change in prmt5 mRNA levels between 18 and 72 hpf, Prmt5 protein expression showed dynamic changes at 18 and 72 hpf, which were accompanied by a change in mobility of Prmt5 protein at 72 hpf compared to other developmental stages.…"
  15. 6615

    Soluble average Klotho level as a prognostic marker for acute kidney injury outcomes: a 90-day follow-up study حسب ShaSha Li (12163175)

    منشور في 2025
    "…Interestingly, we found that sKlotho value was significantly decreased and an alteration in the sKlotho level ran parallel to changes in kidney function in AKI patients. …"
  16. 6616

    The role of Cathepsin inhibitors in RGC damage in hypoxic retina. حسب Emi Nakajima (21703141)

    منشور في 2025
    "…Treatment with neither Odanacatib nor SID26681509 reduced the percentage of PI-positive RGCs, whereas the positive control SNJ-1945 significantly decreased the percentage. Data are means ± SD (n = 3). …"
  17. 6617

    Table 1_Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice.xlsx حسب Rui Tang (298719)

    منشور في 2025
    "…Single-cell sequencing revealed that Resveratrol primarily targeted colonocytes, decreasing genes related to apoptosis and the P53 pathway. …"
  18. 6618

    Table 1_Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head nec... حسب Manting Liu (11207258)

    منشور في 2025
    "…In vivo, SBD intervention significantly reduced bone structural damage and apoptosis, decreasing the rate of empty bone lacunae. …"
  19. 6619

    Impact of Pilates training on gait performance in individuals with unilateral transtibial amputation حسب Janny Mirian Antonelli Tavares (22452771)

    منشور في 2025
    "…The intact side also showed increased step length (<i>p</i> = 0.009), while stance time (<i>p</i> = 0.011) and swing time (<i>p</i> = 0.005) decreased post-training. No changes in asymmetry were observed, regardless of walking speed (<i>p</i> > 0.05). …"
  20. 6620

    Table 1_Silicon application enhances drought resilience in buckwheat: a comparative study of three varieties.docx حسب Jiri Krucky (22299112)

    منشور في 2025
    "…La Harpe had the highest MDA accumulation in roots, increased 5mC levels in leaves, and was the only line with decreased water use efficiency (WUE). Smuga exhibited the highest natural proline level and the strongest proline increase under drought. …"