Abnormal expression of IQGAP1, cleaved caspase-3, BCL‐2, and BAX in the aortic wall of HFD mice and AS plaque. by Shaojun Huang (12489901)

“…<p>(A,B,C) H&E and Oil Red O staining shows the occurrence of AS in the HFD group following 12 weeks of dietary intake. …”

Inhibiting IQGAP1 expression restricts atherosclerotic plaque development. by Shaojun Huang (12489901)

“…(D) The TUNEL assay demonstrates that the number of apoptotic cells are significantly decreased in the AAV-Si-IQGAP1 group. (E,F) Western blot and densitometric analyses of each protein relative to β‐actin reveal decreased expression of IQGAP1, and pro-apoptotic proteins (cleaved caspase-3 and BAX), while YAP and the anti-apoptotic protein BCL-2 are increased in the aortic wall of the AAV-Si-IQGAP1 groups. …”

<b><i>Assessment of Diseases’ Prevalence, Nutrition and Associated Factors in a Conflict-Affected Region: A Study in Leepa Valley, Azad Jammu and Kashmir, Pakistan</i></b> by Zoha Khan (19100603)

“…Objectives: To assess general health and nutritional status, any prevailing diseases and associated factors in residents of the Conflict-Affected Region of Leepa Valley, Azad Jammu and Kashmir, Pakistan. Methodology: A cross-sectional study was executed by circulating a self-structured questionnaire among the patients at a Medical Camp in Leepa as convenient sampling. …”

Impact of mobility in a three-region system with heterogeneous epidemic conditions. by Mousumi Roy (8869412)

“…These simulations underscore that both human mobility and regional epidemic status jointly shape disease transmission dynamics. Mobility has a significant impact in heterogeneous epidemic scenarios, where differences in transmission intensity across regions can lead to outbreaks in low-risk areas through population movement. …”

Supplementary Material for: Non-Prescribed Use of Opioid Agonist Medications and Associations with Non-Fatal Overdoses: A Repeated Cross-Sectional Study Across a Decade of Reduced... by figshare admin karger (2628495)

“…Introduction: Non-prescribed use of opioid agonist treatment (OAT) medications is a public health concern. This study analyses the prevalence of non-prescribed use and non-fatal overdoses in Norway in 2013 and 2023, a period marked by an increasingly flexible OAT regimen, and examines associations between non-prescribed use and non-fatal overdoses. …”

Ameliorating role of co-administration of granulocyte colony stimulating factor and sodium bicarbonate on the skeletal muscle of a rat model of chronic kidney disease (A histologic... by Fayza E. Ahmed (20487163)

“…The CKD group revealed a significant increase in MDA and TNF-α. Furthermore, features of renal injury, muscle degenerative changes, increased collagen and decreased CD34 and myogenin expression were observed. …”

Data_Sheet_1_A randomized double-blinded study assessing the effect of different doses of transnasal dexmedetomidine on the median effective concentration of ropivacaine for a caud... by Fu Wang (10556)

“…</p>Conclusion<p>IN-DEX decreased the EC50 of ropivacaine for the caudal block, and there was a specific dose-dependent effect for IN-DEX. …”

ASIR prediction from 2020 to 2030 by sex. by Majed M. Ramadan (22379116)

“…Bahrain also saw a significant increase in male Age-standardized death rate (ASDR), despite all other countries experiencing a decrease. …”

Deleterious Effects of a GAD65 Monoclonal Autoantibody on Islet Function by Christiane S. Hampe (248347)

“…We recently studied effects of human monoclonal autoantibodies (mAb) derived from a pre-diabetic patient and demonstrated that a GAD65mAb penetrated and accumulated in beta cells and significantly reduced the insulin secretion rate (ISR). …”

Data Sheet 1_A systematic review of the effects of nanoplastics on fish.pdf by Asok K. Dasmahapatra (2275549)

“…Among these, NAPs have superior sorption capacity, a large surface area, and a greater ability to release co-contaminants into tissues, resulting in more complex and harmful effects compared to MAPs and MIPs. …”

SAF-A depletion leads to widespread changes in mRNA splicing. by Judith A. Sharp (21519973)

“…CDF plot illustrating the magnitude of changes in exon inclusion (of all exons significantly changed following SAF-A depletion) in all domain mutants. …”

Singling Out the Electrochemiluminescence Profile in Microelectrode Arrays by Chiara Mariani (20716841)

“…In contrast, a significant narrowing of the ECL profile was observed on Au, indicative of a transition from a catalytic to an oxidative–reductive pathway. …”

Singling Out the Electrochemiluminescence Profile in Microelectrode Arrays by Chiara Mariani (20716841)

“…In contrast, a significant narrowing of the ECL profile was observed on Au, indicative of a transition from a catalytic to an oxidative–reductive pathway. …”

Pre- & post awareness session scores. by Stavia Turyahabwe (9925935)

“…</p><p>Conclusion</p><p>AGB and ACF play a significant role in creating more awareness amongst the community members and identifying more number of cases. …”

VOT vs DOTS TB treatment adherence rates. by Stavia Turyahabwe (9925935)

“…</p><p>Conclusion</p><p>AGB and ACF play a significant role in creating more awareness amongst the community members and identifying more number of cases. …”

Sample size and duration of the pilot study. by Stavia Turyahabwe (9925935)

“…</p><p>Conclusion</p><p>AGB and ACF play a significant role in creating more awareness amongst the community members and identifying more number of cases. …”

<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b> by Rasimcan Meral (5022425)

“…These disorders are defined by abnormal fat distribution, with near-total (generalized lipodystrophy, GL) or partial (partial lipodystrophy, PL; e.g. familial partial lipodystrophy, FPLD) absence of adipocyte mass leading to a decreased ability to store lipids safely. Excess lipids are more likely to be stored in non-adipose tissues, which leads to the metabolic manifestations. …”

Image_3_Education and metabolic syndrome: a Mendelian randomization study.pdf by Dong Liu (115204)

“…</p>Results<p>Education demonstrated a significant negative correlation with the risk of MetS (OR = 0.55, 95% CI = 0.48–0.63, p = 2.18E−51), waist circumference(OR = 0.80, 95% CI = 0.76–0.83, p = 4.98E-33), hypertension (OR = 0.96, 95% CI = 0.95–0.97; p = 4.54E-10), Fasting blood glucose (OR = 0.94, 95% CI = 0.91–0.97, p = 7.58E-6) and triglycerides (OR = 0.83, 95% CI = 0.79–0.87, p = 7.87E-18) while showing a positive association with high-density lipoprotein cholesterol (OR = 1.22, 95% CI = 1.18–1.25, p = 1.45E-31).…”

Image_4_Education and metabolic syndrome: a Mendelian randomization study.pdf by Dong Liu (115204)

“…</p>Results<p>Education demonstrated a significant negative correlation with the risk of MetS (OR = 0.55, 95% CI = 0.48–0.63, p = 2.18E−51), waist circumference(OR = 0.80, 95% CI = 0.76–0.83, p = 4.98E-33), hypertension (OR = 0.96, 95% CI = 0.95–0.97; p = 4.54E-10), Fasting blood glucose (OR = 0.94, 95% CI = 0.91–0.97, p = 7.58E-6) and triglycerides (OR = 0.83, 95% CI = 0.79–0.87, p = 7.87E-18) while showing a positive association with high-density lipoprotein cholesterol (OR = 1.22, 95% CI = 1.18–1.25, p = 1.45E-31).…”

Image_2_Education and metabolic syndrome: a Mendelian randomization study.pdf by Dong Liu (115204)

“…</p>Results<p>Education demonstrated a significant negative correlation with the risk of MetS (OR = 0.55, 95% CI = 0.48–0.63, p = 2.18E−51), waist circumference(OR = 0.80, 95% CI = 0.76–0.83, p = 4.98E-33), hypertension (OR = 0.96, 95% CI = 0.95–0.97; p = 4.54E-10), Fasting blood glucose (OR = 0.94, 95% CI = 0.91–0.97, p = 7.58E-6) and triglycerides (OR = 0.83, 95% CI = 0.79–0.87, p = 7.87E-18) while showing a positive association with high-density lipoprotein cholesterol (OR = 1.22, 95% CI = 1.18–1.25, p = 1.45E-31).…”