Beta cell function derived from routine clinical measures reports and predicts treatment response to immunotherapy in recent-onset type 1 diabetes. by Michelle So (400874)

“…Beta2 score, derived from fasting glucose, C-peptide, HbA1c and insulin dose at 12 weeks, was optimal for predicting QRS>0 following one year of treatment with baricitinib and the other immunotherapies (areas under receiver-operator curve 0.864 and 0.765 respectively). A 6.2% decrease in Beta2 score at week 12 predicted significant improvement in HbA1c (-0.6% or -6 mmol/mol) and insulin use (-0.26 units/kg/day) in combined data from the rituximab, abatacept and anti-thymocyte globulin trials.…”

Table 4_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.xlsx by Ling Yao (16961)

“…Among non-neoplastic digestive diseases, inflammatory bowel disease showed the most pronounced decrease. In contrast, the burden of colorectal cancer has increased annually across all age groups. …”

Table 2_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …”

Cascade Nanozyme-Loaded Sprayable Hydrogels for Fibroblast Rejuvenation and Diabetic Wound Regeneration by Xinyi Zhang (36040)

“…Multifunctional composite wound dressings hold significant promise for diabetic wound healing. However, the detrimental role of the advanced glycation end-products (AGEs)-reactive oxygen species (ROS) cycle in impeding wound repair remains underexplored. …”

Table1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pat... by Boris Jakopovic (9265517)

“…</p>Methods<p>In this study, we performed both qualitative and quantitative proteomic analyses using tandem mass tags (TMT) on CT26 wild type (CT26. …”

Scenario 1. Moderate patient with STAT-ON™. by Daniel Rodriguez-Martin (22411006)

“…Using validated clinical data, we assess the economic impact of early symptom detection facilitated by continuous monitoring. …”

Scenario 2. Advanced patient with STAT-ON™. by Daniel Rodriguez-Martin (22411006)

“…Using validated clinical data, we assess the economic impact of early symptom detection facilitated by continuous monitoring. …”

Table 3_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.xlsx by Zhang-Zhang Ji (21611168)

“…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…”

Table 4_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …”

Table 4_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.xlsx by Zhang-Zhang Ji (21611168)

“…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…”

DataSheet1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic... by Boris Jakopovic (9265517)

“…</p>Methods<p>In this study, we performed both qualitative and quantitative proteomic analyses using tandem mass tags (TMT) on CT26 wild type (CT26. …”

Supporting information. by Maedehsadat Seyedalangi (22655973)

“…The combined treatment of GAP and PCP significantly inhibited microbial growth, with the total viable count in the control sample (C) increasing from 4.39 to 12.08 log CFU/g by day 18, while the combined treatment (P5 + PC) increased only from 3.50 to 9.23 log CFU/g, extending the shelf life from 3 to 12 days. …”

Table 1_Efficacy of valgus osteotomy in treating nonunion of femoral neck fractures post-internal fixation.docx by Haohao Xu (8909687)

“…The mean neck-shaft angle increased from 118.91° to 139.26° (p < 0.001), whereas the Pauwels angle decreased from 62.07° to 46.91° (p < 0.001). …”

Supplementary file 1_Parasite populations of river otter and mink in Western Canada, and the first report of the zoonotic trematode Alaria mustelae in river otter in North America.... by Kyle M. Shanebeck (21766418)

“…Increasing intensities of infection were significantly related to decreasing nutritional condition.…”

<b>Keystone taxa and microbial network complexity, rather than diversity, sustain soil multifunctionality along an elevational gradient in a subtropical karst mountain</b> by Weixue Luo (6070040)

“…</a>Moreover, annual mean temperature and soil pH significantly influenced microbial characteristics, which in turn affected soil EMF. …”

Data Sheet 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Inflammatory markers IFN-γ, IL-4, and IL-1β were elevated in dexamethasone-ETT groups at 3 days, then decreased by 7 days. Macrophage markers CD86 and CD206 were significantly greater in dexamethasone groups compared to regular ETT groups at 7 days (p = 0.002 and p = 0.0213, respectively). …”

Table 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Inflammatory markers IFN-γ, IL-4, and IL-1β were elevated in dexamethasone-ETT groups at 3 days, then decreased by 7 days. Macrophage markers CD86 and CD206 were significantly greater in dexamethasone groups compared to regular ETT groups at 7 days (p = 0.002 and p = 0.0213, respectively). …”

5OMV Inhibits HMGB1-Induced Microvascular Branch Formation in Rat Abdominal Aortic Rings. by Wenyue Hou (10203722)

“…Mean values showing significant differences between the control group and the HMGB1-treated group are indicated by *(<i>P</i> < 0.05) or ** (<i>P</i> < 0.01). …”

Image 2_Biometric parameters and choroidal microstructure in Chinese children with unilateral anisometropia.pdf by Jing Wen (25059)

“…The TCA and LA were significantly greater in hyperopic eyes and significantly lower in myopic eyes compared to normal eyes (all p <0.005). …”

Image 1_Biometric parameters and choroidal microstructure in Chinese children with unilateral anisometropia.pdf by Jing Wen (25059)

“…The TCA and LA were significantly greater in hyperopic eyes and significantly lower in myopic eyes compared to normal eyes (all p <0.005). …”