Table 3_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx by Ömer Bektaş (13827139)

“…Recent genetic-based therapies, such as nusinersen, have transformed disease outcomes. We aimed to evaluate the long-term effects of nusinersen on motor, bulbar, and respiratory functions in both symptomatic and presymptomatic SMA Type 1 patients over a period of up to 4 years.…”

Data Sheet 1_Long-term effects of SGLT2 inhibitors on arrhythmias: a systematic review and meta-analysis.pdf by Peipei Li (552532)

“…The results of meta-analysis revealed that patients treated with SGLT2 inhibitors had a reduced risk of AF/AFL compared with placebo (RR 0.86; 95%CI, 0.77–0.95; I² = 0%; P = 0.003). There was no significant difference in the risk of AF/AFL between the high-dose SGLT2 inhibitors group and the low-dose SGLT2 inhibitors group (RR 0.78; 95%CI, 0.60–1.02; I² = 0%; P = 0.07), although a decreasing trend in the high-dose group was noted. …”

Table 5_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx by Ömer Bektaş (13827139)

“…Recent genetic-based therapies, such as nusinersen, have transformed disease outcomes. We aimed to evaluate the long-term effects of nusinersen on motor, bulbar, and respiratory functions in both symptomatic and presymptomatic SMA Type 1 patients over a period of up to 4 years.…”

Table 2_Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction.xlsx by Yan Du (229593)

“…Introduction<p>Metabolic and gut microbiota (GM) disturbance play a significant role in the complex pathogenesis of substance dependence. …”

Supplementary Material for: Delayed Onset of Central Serous Chorioretinopathy (CSCR) following corticosteroid treatment for Giant Cell Arteritis (GCA): A Case Report by figshare admin karger (2628495)

“…The patient presented with decreased vision in the left eye for 10 days, prompting ophthalmologic evaluation. …”

Table 1_Simultaneous regulation of both lignin and cellulose biosynthesis modifies xylem fiber properties in Populus.xlsx by Jian Li (41607)

“…</p>Results and discussion<p>The transgenic plants exhibited decreased lignin content and a significant increase in cellulose content. …”

Table 1_ZmEXPB7, a β-expansin gene, contributes to drought tolerance in Arabidopsis.docx by Jing Xiong (218613)

“…<p>Drought stress poses a significant threat to maize productivity, highlighting the need to elucidate molecular mechanisms underlying drought tolerance. …”

Data Sheet 1_Frustration and its impact on search and rescue canines.pdf by Sally Dickinson (254872)

“…Our results revealed significant decreases in heart rate variability following frustration and increased latency in the search task, suggesting that frustration had a more pronounced impact on the dogs' physiological state and performance compared to exercise. …”

Video 1_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.mp4 by Xin Fei (20466992)

“…After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”

Data Sheet 1_Response mechanisms of Polygonatum kingianum to temperature stress: implications for cultivation practices.pdf by Huali Qian (11711225)

“…<p>Polygonatum kingianum, a medicinally significant herb indigenous to Yunnan, China, exhibits pronounced sensitivity to temperature affecting its bioactive compound accumulation and growth. …”

Image 1_The change of bacterial community structure helped Salvia miltiorrhiza alleviate the pressure of drought stress.png by Hai Wang (310051)

“…Introduction<p>Drought stress poses a significant threat to plant growth and development, thereby adversely impacting agricultural productivity and ecosystem stability. …”

Supplementary Material for: Single intraluminal delivery of a nitric oxide-donor results in inhibition of intimal thickening in the rabbit femoral artery by Böttger P. (20682794)

“…Linsidomine treatment decreased the intima media ratio significantly (0.65±0.05 vs 1,2±0.2 intima-media-ratio, p<0.05). …”

Data Sheet 1_Splenic compensation alleviates impaired-development of bone marrow terminal erythroid to attenuate anemia in ATPIF1 knockout mice.docx by Jing Feng (177843)

“…ATPIF1-KO mice exhibited significant reductions in peripheral red blood cell (RBC) counts, hemoglobin, and hematocrit. …”

Table 1_Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction.xlsx by Yan Du (229593)

“…Introduction<p>Metabolic and gut microbiota (GM) disturbance play a significant role in the complex pathogenesis of substance dependence. …”

Image 1_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.jpeg by Xin Fei (20466992)

“…After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”

Presentation 1_An integrated transcriptome and physiological analysis of nitrogen use efficiency in rice (Oryza sativa L. ssp. indica) under drought stress.pdf by Yu Wang (12152)

“…Compared to the normal treatment, drought stress led to a significant reduction in NUE across growth stages, with decreases ranging from 2.18% to 31.67%. …”

Video 2_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.mp4 by Xin Fei (20466992)

“…After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”

Whole 16S rRNA gene sequencing reveals differences in the oral microbiota of healthy individuals infected with oral HPV by Toby I. Maidment (15296219)

“…Statistical analysis of alpha- and beta-diversity, as well as taxonomic composition (differential abundance testing), were used to determine differences between-subject groups.</p> <p>We demonstrated (1) significant differences in the abundance of <i>Streptococcus salivarius</i> in oral HPV-negative males; (2) males with low-risk HPV had an increased abundance of several species and (3) decreased abundance of <i>Streptococcus salivarius</i> and <i>Streptococcus parasanguinis</i>. …”

Data Sheet 1_Effect of different 1-methylcyclopropene formulations and dosing on the ripening profile of Tommy Atkins mango fruits.docx by Geoffrey Chomba (20688014)

“…The 1-MCP response was significantly (P≤0.05) affected by maturity stage, 1-MCP treatment concentration, and exposure time. …”

Image 3_Assessment of the brain impact of soccer heading using pupillary light reflex.tif by Junzo Nakao (21429026)

“…In session 2, only CH significantly decreased compared with the baseline. CH significantly decreases from the 20th heading onwards in session 1 compared with session 2 (both at 20 and 30 headings; p < 0.001). …”