Data Sheet 2_Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway.doc by Haoxiang Sun (6396902)

“…Introduction<p>The incidence of diabetes is rising annually, significantly impacting public health and imposing a substantial economic burden on society. …”

Supplementary Material for: Focus on the Blind Spot of Stone Disease: Analysis of Lower Urinary Tract Stone Interventions from 2006 to 2020 using German nationwide inpatient data. by Herout R. (20352174)

“…The significance of changes over time was evaluated via linear regression analysis. …”

Table 2_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Background<p>Chemoresistance is a critical factor compromising the survival of patients with colorectal cancer (CRC). …”

Table 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Background<p>Chemoresistance is a critical factor compromising the survival of patients with colorectal cancer (CRC). …”

Data Sheet 1_Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway.doc by Haoxiang Sun (6396902)

“…Introduction<p>The incidence of diabetes is rising annually, significantly impacting public health and imposing a substantial economic burden on society. …”

Data for the paper: Physiological responses to ultra-high CO₂ levels in an evergreen tree species by tamir klein (4171534)

“…Plant water use decreased at 1600 ppm CO₂ and remained low at 6000 ppm. …”

Table 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Table 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Image 1_COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis.tif by Yuxiao Zheng (8334027)

“…</p>Results<p>COP1 was significantly correlated with poor patient prognosis. …”

Image 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.tif by Haipeng Zhang (3413288)

“…Four hub genes—SRC, TLR8, FCAR, and HIF1A—were identified using LASSO and RF algorithms. …”

Data Sheet 1_Evaluation of the epidemiological and economic impact of the ADLIFE intervention on medium- to long-term in patients with advanced chronic disease.pdf by Igor Larrañaga (5434382)

“…Emergency visits and consultations with primary care professionals decreased significantly, while specialist consultations increased. …”

Table 1_Polygonatum cyrtonema Hua polysaccharides alleviate muscle atrophy and fat lipolysis by regulating the gut microenvironment in chemotherapy-induced cachexia.docx by Rongrong Zhou (3341903)

“…</p><p>Results: This study demonstrated that PCPs significantly mitigated body weight loss, restored muscle fiber atrophy and mitochondrial disorder, alleviated adipose tissue wasting, strengthened the intestinal barrier integrity, and decreased the intestinal inflammation in chemotherapy-induced cachexia. …”

Fig 3 - by Nehal Shawky Nagy (17721213)

“…<p>A) Pathologic assessment of H&E-stained sections of substantia nigra in different studied groups: control, DSMO, and gonadal extract groups show a compact cellular substania nigra in low power, high power shows viable neurons with large, rounded nuclei with open chromatin and a nucleolus (arrows). …”

Data Sheet 1_Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration.zip by Yupeng Li (507508)

“…Atorvastatin enhanced the antioxidant capacity of NPCs and decreased intracellular ROS accumulation. It promoted Nrf2 activation and upregulated the expression of downstream antioxidant factors, thereby exerting a protective effect against oxidative stress–induced injury. …”

Table 1_Ayahuasca partially preserves striatal integrity in juvenile non-human primates exposed to chronic stress: evidence from stereological evaluation.docx by Wigínio Gabriel de Lira-Bandeira (20749421)

“…It may undergo several morphophysiological changes in neuropsychiatric diseases. Depression, a complex psychiatric disorder, affects millions of people around the world and leads to an increased risk of suicide, decreased quality of life, and functional impairment. …”

Table 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.docx by Haipeng Zhang (3413288)

“…Four hub genes—SRC, TLR8, FCAR, and HIF1A—were identified using LASSO and RF algorithms. …”

Hypoxia response and tracheogenesis in <i>PGR</i> mutants. by Daiki Fujinaga (21301129)

“…<p>(A) Relative expression levels of <i>branchless</i> (<i>bnl</i>) in <i>PGR</i> mutants from 0 to 96 hours after puparium formation (APF). …”

Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z... by Peng Ren (337555)

“…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…”

Ictogenic changes in input correlation and adaptation gains are associated with increased dynamical variability during baseline activity. by Scott Rich (9873638)

“…<p><b>A</b>: SLE rate (SLEs/s) as a function of input correlation <i>c</i>. …”

Table 2_Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain bod... by Hannah Godfrey (12256593)

“…Introduction<p>High consumption of dietary carbohydrates (nitrogen-free extract, NFE) in extruded dry foods is postulated as a risk factor for feline obesity, though evidence is limited. …”