Making Cells as a “Nirvana Phoenix”: Precise Coupling of Precursors Prior to ROS Bursts for Intracellular Synthesis of Quantum Dots by Juan Kong (2230867)

“…However, the introduced exogenous reactants and intracellularly produced species, e.g., reactive oxygen species (ROS), often cause cell damage, decreasing the fluorescence of the QDs. Herein, we have found that cell-adaptable selenocystine ((Cys-Se)₂) can be reduced to biocompatible low-valence Se precursors, which could be subsequently hijacked by timely added Ag-glutathione (AgSG) to be transformed into NIR Ag₂Se QDs. …”

Making Cells as a “Nirvana Phoenix”: Precise Coupling of Precursors Prior to ROS Bursts for Intracellular Synthesis of Quantum Dots by Juan Kong (2230867)

“…However, the introduced exogenous reactants and intracellularly produced species, e.g., reactive oxygen species (ROS), often cause cell damage, decreasing the fluorescence of the QDs. Herein, we have found that cell-adaptable selenocystine ((Cys-Se)₂) can be reduced to biocompatible low-valence Se precursors, which could be subsequently hijacked by timely added Ag-glutathione (AgSG) to be transformed into NIR Ag₂Se QDs. …”

S1 Raw data - by Xiaoyi Shi (3825754)

“…Our results indicated that PGAM5 was significantly elevated by I/R injury, and predominantly localized in the necrosis area. …”

Minimal data set. by Fu-Lin Yu (21446056)

“…However, the metabolic mechanisms underlying arsenic’s effects on muscle function and pathogenesis remain incompletely understood. In this study, we investigated the role of mitochondrial fatty acid oxidation in arsenic-induced muscular damage using mouse skeletal muscle C2C12 cells. …”

Making Cells as a “Nirvana Phoenix”: Precise Coupling of Precursors Prior to ROS Bursts for Intracellular Synthesis of Quantum Dots by Juan Kong (2230867)

“…However, the introduced exogenous reactants and intracellularly produced species, e.g., reactive oxygen species (ROS), often cause cell damage, decreasing the fluorescence of the QDs. Herein, we have found that cell-adaptable selenocystine ((Cys-Se)₂) can be reduced to biocompatible low-valence Se precursors, which could be subsequently hijacked by timely added Ag-glutathione (AgSG) to be transformed into NIR Ag₂Se QDs. …”

Making Cells as a “Nirvana Phoenix”: Precise Coupling of Precursors Prior to ROS Bursts for Intracellular Synthesis of Quantum Dots by Juan Kong (2230867)

“…However, the introduced exogenous reactants and intracellularly produced species, e.g., reactive oxygen species (ROS), often cause cell damage, decreasing the fluorescence of the QDs. Herein, we have found that cell-adaptable selenocystine ((Cys-Se)₂) can be reduced to biocompatible low-valence Se precursors, which could be subsequently hijacked by timely added Ag-glutathione (AgSG) to be transformed into NIR Ag₂Se QDs. …”

The chemical structure of melatonin. by Xiaoyi Shi (3825754)

“…Our results indicated that PGAM5 was significantly elevated by I/R injury, and predominantly localized in the necrosis area. …”

Regulation of Rice Grain Weight by Fatty Acid Composition: Unveiling the Mechanistic Roles of <i>OsLIN6</i> by OsARF12 by Haoran Tian (6706925)

“…However, the inner mechanism is still unclear and needs to be further studied. In this study, we identified that oleic acid (C18:1) negatively correlates while linoleic acid (C18:2) positively correlates with rice grain weight. …”

Systemic injection of TSA reduces hearing loss in <i>Col4a3</i> KO mice. by Yoon Seok Nam (20678482)

“…(C) The tone burst results showed a significant decrease at 8, 16, 24, and 32 kHz in TSA-treated <i>Col4a3</i> KO mice at 6–7 weeks. …”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

“…Such dual cross-linkable group functionalization brought additional thiol–ene click reactions upon exposure to enhance intercluster polymerization, which significantly improved the lithography sensitivity of TOCs, with the required exposure energy being reduced by over 70% (decreasing from >1000 μC/cm² of alkenyl-TOC to <300 μC/cm² of alkenyl/thiol-TOC). …”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

“…Such dual cross-linkable group functionalization brought additional thiol–ene click reactions upon exposure to enhance intercluster polymerization, which significantly improved the lithography sensitivity of TOCs, with the required exposure energy being reduced by over 70% (decreasing from >1000 μC/cm² of alkenyl-TOC to <300 μC/cm² of alkenyl/thiol-TOC). …”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

“…Such dual cross-linkable group functionalization brought additional thiol–ene click reactions upon exposure to enhance intercluster polymerization, which significantly improved the lithography sensitivity of TOCs, with the required exposure energy being reduced by over 70% (decreasing from >1000 μC/cm² of alkenyl-TOC to <300 μC/cm² of alkenyl/thiol-TOC). …”

<i>TcPiezo-CKO</i> responses to hypoosmotic stress. by Guozhong Huang (673424)

“…(D) Tet-induced <i>TcPiezo2 Tet-OFF</i> cells (+Tet) had a significant decrease of intracellular Ca²⁺ rise, compared to non-induced cells (-Tet). 100 µ M EGTA was added to remove extracellular Ca^2<i>+</i>, abolishing Ca²⁺ entry, as indicated. …”

This figure illustrates the impact of <i>Lactobacillus reuteri</i> supplementation on cytokine concentrations in a mouse model of colitis induced by dextran sulfate sodium (DSS). by Mohsen Nazari (6299819)

“…<b>(C)</b> Interleukin-6 (IL-6): DSS treatment caused a significant increase in IL-6 levels, which were significantly mitigated in the <i>L. reuteri</i>-treated group. …”

Heatmap analysis for technical reproducibility of Cohort #1 CP dataset (28wk-old WT and R14^Δ/+). by Brian Foo (19273132)

Partial behavioral switching. by Hiroyuki Ichijo (13891153)

Effects of activators and inhibitors on TcPiezo channels. by Guozhong Huang (673424)

“…Downregulation of <i>TcPiezo1</i> expression significantly decreased Dooku1-evoked TcPiezo1-mediated Ca²⁺ entry (left bar graph) but had no effect on Dooku1-evoked TcPiezo2-mediated Ca²⁺ release (right bar graph). …”

Reversible Adsorption and Interfacial Photoisomerization of Azobenzene Surfactants Studied by QCM by Maren Umlandt (9638121)

“…We further quantify the photoisomerization kinetics at the interface, revealing that the isomerization rate constant decreases with a lower <i>trans</i> isomer concentration due to a transition from a diffuse multilayer to a confined double-layer structure. …”

PERCOM, an unbiased and easily-accessible protein-centric analysis workflow. by Brian Foo (19273132)

S1 Raw images - by Yoon Seok Nam (20678482)

“…The results demonstrate that TSA significantly protects the hearing of KO mice compared to the untreated group. …”