Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway by figshare admin karger (2628495)

“…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …”

Table1_Carex parva and Carex scabrirostris adopt diverse response strategies to adapt to low-light conditions.docx by Wanting Liu (2917691)

“…Introduction<p>In recent years, the visible light intensity of lawns has significantly decreased due to obstructions caused by urban shading objects. …”

Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx by Weiguang Lv (8622405)

“…Protein and mRNA expression analyses revealed that high-dose baicalein upregulated the expression of FTH1, GPX4, SLC7A11, SLC3A2 and Nrf2, while downregulating ACSL4 significantly. …”

SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool by Anna Rindorf (6217391)

“…Almost all management strategies except current management led to overall decreases in effort and as a result, the general ecosystem impact to a level where GES was attained (habitats and foodwebs) or the impact was decreased by at least 20% (bycatch). …”

Supplementary file 1_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.docx by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Table 2_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.csv by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Plant species loss reduces rare soil microbes through diversity effect amplified by multitrophic interactions by Jie Li (14726914)

“…We found that the removal of rare forbs, rather than dominant species and common plants, significantly decreased the richness of soil bacteria and fungi by decreasing rare microbial taxa in later years. …”

Table 1_Exploring the role of LOX family in glioma progression and immune modulation.docx by Chen Liu (75209)

“…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”

Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg by Chen Liu (75209)

“…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”

Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion by Qingbo Lv (21676001)

“…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …”

Image 1_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Table 1_Radiofrequency ablation vs. cryoablation for pediatric atrioventricular nodal reentrant tachycardia in the era of three-dimensional electroanatomical mapping.docx by Yao-Wei Chan (20639414)

“…The minor complication rates, including transient AV block, did not differ significantly (14.5% vs. 11.5%, p > 0.99). The RF group had a significantly shorter procedure time (111 vs. 153.5 min, p = 0.005). …”

Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

“…Additionally, gene and protein expression levels of P-glycoprotein (P-gp) and organic cation transporter 1 (OCT1) were assessed to explore the mechanisms by which HH affects pitolisant’s pharmacodynamics.</p>Results<p>A 40 mg/kg dose of pitolisant significantly improved learning, memory, cognitive, and motor functions in sleep-deprived mice under HH conditions (P < 0.05). …”

Supplementary Material for: Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights by Wang B. (4026758)

“…Conclusion The SO2 inhalation protocol effectively establishes a CB model in dogs. SCT effectively treats CB by reducing mucin levels and may lower MUC5AC expression by decreasing acetylcholine and CHRM3.…”

Data Sheet 1_Inhibition of biofilm formation and preformed biofilm in Acinetobacter baumannii by resveratrol, chlorhexidine and benzalkonium: modulation of efflux pump activity.zip by Antonella Migliaccio (12052292)

“…The combination of RV with CHX and BZK additively decreased minimal biofilm eradicating concentrations in A. baumannii strains.…”

Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx by Xin Yu (124814)

“…Cellular experiments using A549 and Beas2B cells showed that PIN significantly reduced TGF-β1-induced mesenchymal marker expression while increasing epithelial marker expression. …”

Table 1_Litter quality outweighs climate in driving grassland root decomposition.docx by Jingjing Yang (119262)

“…With respect to biotic factors, grazing (+7.51%) significantly increased decomposition, whereas vegetated soil (−27.84%), increased plant species richness (−4.99%), increased root litter richness (−5.93%), home-field decomposition (−4.34%), and soil biota exclusion (−10.40%) decreased it.…”

Table 1_Refrigerator ownership and the nutrition-health trade-off: evidence from Chinese households.docx by Manli Zheng (21288128)

“…The ratios of energy derives from fat and protein rose by 0.104 and 0.018 percentage points, respectively, while the carbohydrate energy ratio decreases by 0.12 percentage points, indicating a shift towards a higher energy-dense diet. …”

Supplementary file 1_Association between olfactory dysfunction and gustatory dysfunction: evidence from the National Health and Nutrition Examination Survey.docx by Yi Yang (116183)

“…Similarly, the questionnaire data revealed that OD significantly increased the odds of GD. However, hyposmia OD decreased the odds of hypogeusia GD using the tongue-tip taste measurement.…”