Image1_Impaired Mycobacterium tuberculosis-specific T-cell memory phenotypes and functional profiles among adults with type 2 diabetes mellitus in Uganda.jpeg by Phillip Ssekamatte (10217206)

“…CD4⁺ TNF and CD8⁺ IL-17A production were significantly decreased in participants with LTBI-DM compared to those with LTBI-only [0.38 (0.33-0.50) vs 0.62 (0.46-0.87); (p=0.004) and 0.29 (0.16-0.42) vs 0.47 (0.29-0.52); (0.017)] respectively. …”

Data Sheet 1_Dynamics of soil nutrients and biological activities along an infection chronosequence of pine wilt disease in subtropical Masson pine forests.docx by Xueyu Song (3600464)

“…The results revealed that soil non-capillary porosity, clay, microbial biomass carbon and microbial biomass nitrogen decreased significantly in 6 years forests. Available potassium consistently decreased with longer invasion periods, while soil polyphenol oxidase, leucine amino peptidase, and available phosphorous peaked in 6 years forests and then declined over time. …”

Data for “Impact of multiscale heterogeneous sediments and boundary conditions on dispersivity spatial variations” by Ziqi Ma (12099365)

“…These experiments contain various sedimentary structures, including several nearly-homogeneous column tests, a heterogeneous column test, a horizontally stratified tank experiment, a randomly filled tank experiment, and a three-dimensional tank experiment utilizing an analogous simulation to a field-scale site. …”

Data Sheet 1_Cognitive component of auditory attention to natural speech events.pdf by Nhan Duc Thanh Nguyen (20506628)

“…Importantly, the component decreases in strength but is still significantly observable in increasingly realistic paradigms of multi-talker environments. …”

Supplementary file 1_Dachaihu decoction ameliorates abnormal behavior by regulating gut microbiota in rats with propionic acid-induced autism.docx by Yangyang Zhang (608493)

“…Meanwhile, the small clinical trial revealed that DCHD significantly alleviated the core symptoms of ASD, with decreased ADOS-2 and ABC scale scores. …”

Data Sheet 1_Dachaihu decoction ameliorates abnormal behavior by regulating gut microbiota in rats with propionic acid-induced autism.zip by Yangyang Zhang (608493)

“…Meanwhile, the small clinical trial revealed that DCHD significantly alleviated the core symptoms of ASD, with decreased ADOS-2 and ABC scale scores. …”

Phytochemical contents of B1W. by Yongjin Lee (1428223)

“…B1W also showed a trend towards decreasing serum C-telopeptide of collagen type 1 levels in OVX mice. …”

Primer sequences used in this study. by Yongjin Lee (1428223)

“…B1W also showed a trend towards decreasing serum C-telopeptide of collagen type 1 levels in OVX mice. …”

Protective role of <i>N</i>-acetyl-l-tryptophan against hepatic ischemia-reperfusion injury via the RIP2/caspase-1/IL-1β signaling pathway by Jianxin Wang (35827)

“…Similarly, IL-1β activity and caspase-1 activity were significantly decreased in the H₂O₂ group when compared with the controls, after l-NAT intervention.…”

Table 1_Associations between gut microbiota and diet composition of three arid-adapted rodent species from the Inner Mongolia grassland.doc by Muha Cha (4002941)

“…In contrast, the consumption of animal-based foods significantly decreased microbial diversity. This finding suggests a potential link between the host’s genetic background, dietary composition, and the gut microbiota.…”

Table_1_Baicalin enhances antioxidant, inflammatory defense, and microbial diversity of yellow catfish (Pelteobagrus fulvidraco) infected with Aeromonas hydrophila.DOCX by Pupu Yan (19710400)

“…Moreover, baicalin significantly enhanced the operational taxonomic unit (OTU) count in A. hydrophila-infected yellow catfish (P < 0.05), restoring the abundance of Barnesiellaceae, Enterobacteriaceae, Plesiomonas, and UBA1819 (P < 0.05).…”

Supplementary file 1_Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol.docx by Jiali Liu (327739)

“…Mechanistic investigations revealed that KA modulated fatty acid metabolism, retinol metabolism, and arachidonic acid metabolism by regulating the expression of key metabolic enzyme genes such as SCD, SCD2, FADS2, and CYP4A8, and significantly influenced the activity of the PPAR signaling pathway. …”

Table_1_Baicalin enhances antioxidant, inflammatory defense, and microbial diversity of yellow catfish (Pelteobagrus fulvidraco) infected with Aeromonas hydrophila.DOCX by Pupu Yan (19710400)

“…Moreover, baicalin significantly enhanced the operational taxonomic unit (OTU) count in A. hydrophila-infected yellow catfish (P < 0.05), restoring the abundance of Barnesiellaceae, Enterobacteriaceae, Plesiomonas, and UBA1819 (P < 0.05).…”

Effects of vidarabine, V2E, V3E and V5E on AC activity in the heart of WT and AC5KO mice. by Kenji Suita (750993)

“…<p>(A) Vidarabine (Vida), V2E, V3E and V5E similarly and significantly decreased ISO (50 µmol/L)-stimulated AC activity in the WT heart in a dose-dependent manner. …”

Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein by Xiangchao Jia (21392720)

“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”

Table 1_Regulation of DNA methylation in lesional tissue of children with atopic dermatitis.docx by Demet Kartal (20817926)

“…</p>Results<p>The mRNA expression levels of DNMT3A genes were significantly increased, while the mRNA expression levels of DNMT3B, TET1, and TET2 genes were statistically significantly reduced in the lesional tissue of patients compared to the control group. …”

High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection by Yiwei Zhang (1448599)

“…Intravenous administration of the Omp38-specific mAbs significantly improved the survival rate and reduced the bacterial load in a mouse model of lethal <i>A. baumannii</i> infection. …”

Data Sheet 1_The response regulator CrsR positively regulates ansamitocin P-3 biosynthesis in Actinosynnema pretiosum.docx by Peipei Zhang (1360440)

“…Deletion of the response regulator gene crsR drastically decreased AP-3 production. RNA-seq revealed CrsR’s global regulatory role, significantly altering transcription of primary metabolic genes, especially those in purine metabolism. …”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…The regulatory mechanism of MrgC on UPR^mt was further explored in N2a and 293T cells.</p>Results<p>Mice with bone cancer pain showed improved mRNA and protein levels of UPR^mt-related molecules, increased MMP and ATP, decreased mitochondrial ROS levels in the spinal cord after receiving an intrathecal injection of BAM8-22. …”

Table 1_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx by Ik-Hwan Han (8605281)

“…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163⁺ M2 macrophages, and increased CD8⁺ T cell infiltration in tumor tissues. …”