Video 3_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

Video 1_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

Figure 5 from Membrane-bound Heat Shock Protein mHsp70 Is Required for Migration and Invasion of Brain Tumors by Maxim Shevtsov (15023874)

“…<p>Application of Hsp70 inhibitors decreases the brain tumor cell migratory activity. …”

Image 1_Cannabis use is associated with alterations in NLRP3 inflammasome related gene expression in monocyte-derived macrophages from people living with HIV.tif by Kyle C. Walter (22578179)

“…When treated with CBD and IL-1β, we observed a significant increase in both IL1β (3-fold, p < 0.01) and IL18 (2-fold, p < 0.01) expression compared to vehicle. …”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…<p>The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”

Data_Sheet_1_Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke.docx by Jae-Sung Lim (532986)

“…</p>Methods<p>Using a prospective stroke registry, we identified patients who displayed normal cognitive function at baseline evaluation within a year post-stroke and received at least one subsequent assessment. …”

Data Sheet 1_Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study.pdf by Zhen Wang (72451)

“…The mean survival time before diabetes onset was significantly longer in prediabetic patients who received SAIDEs than in those in other groups.…”

Data Sheet 2_A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury.pdf by Yuichi Akama (17892940)

“…Our data showed that B-1a cell numbers and frequencies in the pleural and peritoneal cavities were significantly decreased in sepsis. Neutrophils co-cultured with B-1a cells significantly increased B-1a cell internalization via trogocytosis. …”

Data Sheet 1_A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury.pdf by Yuichi Akama (17892940)

“…Our data showed that B-1a cell numbers and frequencies in the pleural and peritoneal cavities were significantly decreased in sepsis. Neutrophils co-cultured with B-1a cells significantly increased B-1a cell internalization via trogocytosis. …”

Assessment of calcium events, pERK levels, NMDA receptor expression and extracellular zinc levels in <i>slc13a5</i> mutants. by Deepika Dogra (21072023)

“…Untreated WTs, n = 4; DMSO-treated WTs, n = 3. Data are Mean ±  S.E.M., ns: no significant changes observed, * P ≤  0.05, **P ≤  0.01, ***P ≤  0.001- Unpaired <i>t</i> test. …”

Impact of Oral Semaglutide on Kidney Outcomes in People with Type 2 Diabetes: Results from the SOUL Randomized Trial by Johannes F. E. Mann (22017555)

“…</p><p dir="ltr">RESULTS</p><p dir="ltr">Among 9,650 participants, mean eGFR was 73.8 mL/min/1.73 m2 and follow-up was 47.5 months. …”

Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx by Yuko Horikoshi (12202859)

“…</p>Methods<p>This was a cross-sectional study conducted in 2024. We evaluated CAVI and its associated factors in 590 children aged 6–15 years (mean age: 10.5 years, 51.0% female). …”

Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx by José Fidel Baizabal-Carvallo (11416508)

“…Responses were divided into three tiers.</p>Results<p>We studied 230 consecutive patients with PD. There were 130 (56.5%) male patients, with the mean age at evaluation of 67.7 ± 11.06 years. …”

Identification of novel pathogenic mutations in <i>ATP6V0A4</i> associated with distal renal tubular acidosis and analysis of wild-type expression in glomerular disease by Yaru Jiang (17458815)

“…If untreated, it can result in a significant electrolyte imbalance and progressive chronic kidney disease (CKD). …”

Supplementary file 1_Soluble suppression of tumorigenicity-2 changes during cardiotoxic cancer treatment: a systematic review and meta-analysis.docx by Luca Fazzini (22599380)

“…Using random-effects models, mean differences (MD), and standardized MD (SMD), we analyzed (i) ST2 longitudinal changes, (ii) the association between ST2 and cardiotoxicity [defined through left ventricular ejection fraction (LVEF)] providing pooled estimates of correlations, and (iii) the SMD variations among biomarkers.…”

Table 1_Effects of two kinds of vestibular function training on reducing motion sickness in college students.docx by Linyao Shi (20684204)

“…</p>Results<p>After training, both groups’ Graybiel scores, blood pressure, high-frequency power (HF), and root mean square of successive differences (rMSSD) between adjacent normal heartbeats significantly decreased. …”

Table 1_Laboratory comparison of consumer-grade and research-established wearables for monitoring heart rate, body temperature, and physical acitivity in sub-Saharan Africa.docx by Stefan Mendt (834379)

“…Each variable was simultaneously tracked by consumer-grade and established research-grade devices to evaluate the validity of the consumer-grade devices. We statistically compared the data agreement using Pearson’s correlation r, Lin’s concordance correlation coefficient (LCCC), Bland-Altman method, and mean absolute percentage error.…”

CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells. by Jovana Deretic (13113617)

“…<i>n</i> > 600 cells for control and >400 cells for CCDC66 depletion. The mean cilia length in CCDC66-depleted cells decreased to 0.67-fold compared to the mean control length. …”

Data Sheet 1_Comparative efficacy and safety of antidiabetic agents for post-transplant diabetes mellitus: a network meta-analysis.docx by Shanbiao Hu (15063765)

“…Background<p>Post-transplant diabetes mellitus (PTDM) significantly compromises patient and graft outcomes. …”

Table 1_Efficacy and safety of live combined Bacillus subtilis and Enterococcus faecium in patients with constipation: a meta-analysis of randomized controlled trials.docx by Wenwen Li (735004)

“…The defecation difficulty score tended to decrease in the experimental group relative to that in the control group, although this did not reach statistical significance [SMD (95% CI) = −1.924 (−3.947 to 0.099); p = 0.062]. …”