Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg by Katrina S. Hofstetter (17545425)

“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... by Neves P.D.M.M. (20408168)

“…The kidney is a frequent target of SARS-CoV-2, potentially developing lesions in glomeruli, vessels, and tubulointerstitium in response to this infection. Herein we present the analysis of the first large Latin American cohort of adult patients undergoing kidney biopsy due to COVID-19-associated kidney disorders. …”

Data Sheet 1_Soil microbiome dysbiosis and rhizosphere metabolic dysfunction drive continuous cropping obstacles of Codonopsis tangshen.docx by Dabing Xu (18961138)

“…However, their abundance decreased significantly under continuous cropping, ultimately disrupting soil carbon cycling. …”

Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”

Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”

Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”

Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx by Ping Zhao (47228)

“…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19⁺ B cells and CD14⁺ monocytes, but significantly decreased on CD56⁺ NK cells.We identified a distinct CD226⁺CD19⁺ B cell subset that exhibited pathogenic features in pSS. …”

Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”

Data Sheet 1_Unveiling frailty: comprehensive and sex-specific characterization in prematurely aging PolgA mice.pdf by Dilara Yılmaz (19710658)

“…While these approaches have been applied to aging mice, their effectiveness in prematurely aging mouse models such as PolgA^D257A/D257A (PolgA) has not been completely explored. We demonstrated that frailty became evident in PolgA mice around 40 weeks, validated through body weight loss, reduced walking speed, decreased physical activity, and weaker grip strength. …”

Data and code for "Sympathetic vasomotion as an early marker of hemorrhage." by Peter Pellegrino (20875475)

“…The difference in the vasomotion profiles between the innervated and denervated kidneys increased significantly prior to increases in heart rate or decreases in blood pressure. …”

Water bridges by Raman Jangra (19231711)

“…To delineate the structural role of water molecules in shaping the interactions between RNA and proteins, we comprehensively analyzed a dataset of 329 high-resolution crystal structures of RNA–protein complexes to identify water-mediated hydrogen-bonded contacts at the RNA–protein interface. …”

Supplementary Figures_Fainshtein.pdf by Kfir Sharabi (21415808)

“…Furthermore, we show that depleting <i>Hdac1</i> in mouse primary hepatocytes and liver tissue reduces glucose production, consistent with decreased PGC-1α activity. …”

Mapping global urban inequality under climate change and its interaction with sustainable development by Yinshuai Li (20382495)

“…<p>Global cities are significantly affected by climate change, leading to increased inequality and further vulnerability among marginalized groups. …”

Table_2_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table_3_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table_1_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xlsx by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Supplementary file 1_Interspecific association characteristics of Alternanthera philoxeroides-invaded communities and their latitudinal variations.docx by Hao Wu (65943)

“…The association intensity between terrestrial accompanying species significantly decreased with increasing latitude, and the association intensity between aquatic accompanying species varied weakly along the latitudinal gradient. …”

Data Sheet 2_Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.pdf by Anita Meinke (14137836)

“…</p>Results<p>Spinal flattening was observed during micro-gravity exposure, with changes most pronounced in the upper lumbar and lower thoracic spine. Mean-normalized area between the back and backpack decreased significantly in micro-gravity compared to earth-gravity (p = 0.001), but not during hyper-gravity (p = 1.00). …”

Data Sheet 1_Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.pdf by Anita Meinke (14137836)

“…</p>Results<p>Spinal flattening was observed during micro-gravity exposure, with changes most pronounced in the upper lumbar and lower thoracic spine. Mean-normalized area between the back and backpack decreased significantly in micro-gravity compared to earth-gravity (p = 0.001), but not during hyper-gravity (p = 1.00). …”

Image 1_Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture syste... by Yunfeng Yao (7136525)

“…It was found that both PTGM and PT remarkably decreased the average bulk density (BD), while elevated the mean soil porosity (SP) in 0–30 cm soil layer. …”