Showing 16,961 - 16,980 results of 18,072 for search 'significant ((((gap decrease) OR (((we decrease) OR (greatest decrease))))) OR (a decrease))', query time: 0.69s Refine Results
  1. 16961

    Table 2_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx by Ik-Hwan Han (8605281)

    Published 2025
    “…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163<sup>+</sup> M2 macrophages, and increased CD8<sup>+</sup> T cell infiltration in tumor tissues. …”
  2. 16962

    Further characterization of N19 and calcium dependence. by Elham Karamooz (2584474)

    Published 2025
    “…<p>(<b>A</b>) N19 decreases MR1 presentation of Mtb when added at the same time as infection. 25µM N19 was added to BEAS-2Bs the same time as Mtb (MOI 8). …”
  3. 16963
  4. 16964

    Short-term antiretroviral therapy may not correct the dysregulations of plasma virome and cytokines induced by HIV-1 infection by Yingying Ma (3617810)

    Published 2025
    “…Notably, most dysregulated cytokines were not fully restored by ART, with extremely abnormal levels of IL-10, GM-CSF, VEGF, and eotaxin, and a significantly increased level of plasma I-FABP. …”
  5. 16965

    Data Sheet 1_Effects of different fermentation temperatures on microbiomes of cigar tobacco leaves.pdf by Yun Jia (1583794)

    Published 2025
    “…</p>Results<p>The bacterial biomass increased initially and peaked at 8.4 × 10<sup>9</sup> copies/g at 35°C, then decreased as the temperature rose. The fungal biomass exhibited a downward trend with increasing temperature, reaching a maximum of 3.9 × 10<sup>6</sup> copies/g at 30°C. …”
  6. 16966

    Table 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.xlsx by Huijing Tang (19133347)

    Published 2025
    “…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”
  7. 16967

    Supplementary file 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.docx by Huijing Tang (19133347)

    Published 2025
    “…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …”
  8. 16968

    Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway by figshare admin karger (2628495)

    Published 2025
    “…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …”
  9. 16969

    Table1_Carex parva and Carex scabrirostris adopt diverse response strategies to adapt to low-light conditions.docx by Wanting Liu (2917691)

    Published 2024
    “…Introduction<p>In recent years, the visible light intensity of lawns has significantly decreased due to obstructions caused by urban shading objects. …”
  10. 16970

    Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx by Weiguang Lv (8622405)

    Published 2025
    “…Protein and mRNA expression analyses revealed that high-dose baicalein upregulated the expression of FTH1, GPX4, SLC7A11, SLC3A2 and Nrf2, while downregulating ACSL4 significantly. …”
  11. 16971

    Supplementary file 1_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.docx by Jennifer J. Barb (9153014)

    Published 2025
    “…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”
  12. 16972

    Table 2_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.csv by Jennifer J. Barb (9153014)

    Published 2025
    “…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”
  13. 16973

    Table 1_Exploring the role of LOX family in glioma progression and immune modulation.docx by Chen Liu (75209)

    Published 2025
    “…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”
  14. 16974

    Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg by Chen Liu (75209)

    Published 2025
    “…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”
  15. 16975

    Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion by Qingbo Lv (21676001)

    Published 2025
    “…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …”
  16. 16976

    Table 1_Radiofrequency ablation vs. cryoablation for pediatric atrioventricular nodal reentrant tachycardia in the era of three-dimensional electroanatomical mapping.docx by Yao-Wei Chan (20639414)

    Published 2025
    “…The minor complication rates, including transient AV block, did not differ significantly (14.5% vs. 11.5%, p > 0.99). The RF group had a significantly shorter procedure time (111 vs. 153.5 min, p = 0.005). …”
  17. 16977

    Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

    Published 2025
    “…Additionally, gene and protein expression levels of P-glycoprotein (P-gp) and organic cation transporter 1 (OCT1) were assessed to explore the mechanisms by which HH affects pitolisant’s pharmacodynamics.</p>Results<p>A 40 mg/kg dose of pitolisant significantly improved learning, memory, cognitive, and motor functions in sleep-deprived mice under HH conditions (P < 0.05). …”
  18. 16978

    Supplementary Material for: Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights by Wang B. (4026758)

    Published 2025
    “…Conclusion The SO2 inhalation protocol effectively establishes a CB model in dogs. SCT effectively treats CB by reducing mucin levels and may lower MUC5AC expression by decreasing acetylcholine and CHRM3.…”
  19. 16979

    Data Sheet 1_Inhibition of biofilm formation and preformed biofilm in Acinetobacter baumannii by resveratrol, chlorhexidine and benzalkonium: modulation of efflux pump activity.zip by Antonella Migliaccio (12052292)

    Published 2024
    “…The combination of RV with CHX and BZK additively decreased minimal biofilm eradicating concentrations in A. baumannii strains.…”
  20. 16980

    Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx by Xin Yu (124814)

    Published 2025
    “…Cellular experiments using A549 and Beas2B cells showed that PIN significantly reduced TGF-β1-induced mesenchymal marker expression while increasing epithelial marker expression. …”